The influence of solution viscosity on nasal spray deposition and clearance

International Journal of Pharmaceutics

Volumn 43, Issue 3, 1988, Pages 221-224

  Pennington, A K ^a   Ratcliffe, J H ^a   Wilson, C G ^a   Hardy, J G ^b  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

^b SANOFI   (France)

Author keywords

Nasal spray; Solution viscosity

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE; PENTETATE TECHNETIUM TC 99M; RADIOISOTOPE;

ADULT; DRUG CLEARANCE; FEMALE; HUMAN; HUMAN EXPERIMENT; INHALATIONAL DRUG ADMINISTRATION; MALE; NORMAL HUMAN; PRIORITY JOURNAL;

EID: 0023879968     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(88)90277-3     Document Type: Article

References (9)

1. Distribution and removal of human serum albumin - technetium-99m instilled intranasally
2. Deposition and clearance of nasal sprays
3. Intranasal drug delivery by spray and drops
4. Phagocytosis, mucous flow, and ciliary action
5. Nasal sprays and polyps
6. The nasal distribution of metered dose inhalers
7. Clearance of inhaled particles from the human nose
8. Nasal mucociliary clearance under various conditions
9. A roentgenographic method for measuring nasal mucous velocity