Dopaminergic stimulation disrupts sensorimotor gating in the rat

Psychopharmacology

Volumn 94, Issue 4, 1988, Pages 507-514

  Mansbach, Robert S ^a   Geyer, Mark A ^a   Braff, David L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amphetamine; Apomorphine; Dopamine; Haloperidol; Prepulse inhibition; Rats; Schizophrenia; Sensory gating; Startle

Indexed keywords

AMPHETAMINE; APOMORPHINE; DOPAMINE RECEPTOR; HALOPERIDOL;

ANIMAL EXPERIMENT; DOSE RESPONSE; MALE; NONHUMAN; PSYCHOLOGICAL ASPECT; RAT; SCHIZOPHRENIA;

ANIMAL; APOMORPHINE; DEXTROAMPHETAMINE; HALOPERIDOL; MALE; NEURAL INHIBITION; RATS; RATS, INBRED STRAINS; RECEPTORS, DOPAMINE; STARTLE REACTION; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023870896     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/BF00212846     Document Type: Article

References (35)

1. Effects of 6-hydroxydopamine lesions of locus coeruleus on startle in rats
2. Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia
3. Attention, habituation, and information processing in psychiatric disorders
4. The time course of information processing deficits in schizophrenia
5. Prestimulus effects on human startle reflex in normals and schizophrenics
6. Information processing for masked and unmasked stimuli in schizophrenia and old age
7. Mechanism of action of neuroleptic drugs
8. The classification of dopamine receptors: Relationship to radioligand binding
9. Neurochemical modulation of sensory-motor reactivity: Acoustic and tactile startle reflex
10. Effects of apomorphine and haloperidol in the acoustic startle response in rats
11. Effects of d-and l-amphetamine on habituation and sensitization of the acoustic startle response in rats
12. Antagonism of apomorphine-enhanced startle by α1-adrenergic antagonists
13. Heterogenous functions of discrete serotonergic pathways in brain
14. The more or less startling effects of weak prestimuli
15. Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input
16. Drug-induced motor behavior
17. Sensitization to amphetamine and tolerance to cocaine and phencyclidine stimulation in mice
18. Involvement of norepinephrine in startle arousal after acute and chronic d-amphetamine administration
19. Two dissociable components of behavioral sensitization following repeated amphetamine administration
20. Biochemical aspects of schizophrenia
21. Disorders of attention and perception in early schizophrenia
22. Schedule-controlled behavior and the effects of drugs
23. Information processing and attentional functioning in the developmental course of schizophrenic disorders
24. Alterations in the function of the nucleus locus coeruleus: A possible model for studies of anxiety
25. Information processing abnormalities: Trait- and state-dependent components
26. Backward masking as a measure of attention in schizophrenia
27. Noradrenergic influence on the prepulse inhibition of acoustic startle
28. Behavioral and neurochemical correlates of repeated d-amphetamine administration
29. Long-term administration of d-amphetamine: Progressive augmentation of motor activity and stereotypy
30. Stimulant-induced psychosis: an evaluation of animal models
31. Schizophrenia and dopamine regulation in the mesolimbic system
32. Central dopamine hyperactivity in rats mimics abnormal acoustic startle response in schizophrenics
33. Stereotaxic mapping of the monoamine pathways in the rat brain