Pulmonary toxicity of doxorubicin administered by in situ isolated lung perfusion in dogs

Cancer

Volumn 61, Issue 7, 1988, Pages 1320-1325

  Minchin, Rodney F ^a,b   Johnston, Michael R ^a,c   Schuller, Hildergard M ^a   Aiken, Michael A ^a   Boyd, Michael R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXORUBICIN;

ANIMAL EXPERIMENT; DOG; HISTOLOGY; LUNG TOXICITY; MALE; NONHUMAN; REGIONAL PERFUSION;

ALANINE TRANSAMINASE; ANIMAL; ASPARTATE AMINOTRANSFERASES; COMPARATIVE STUDY; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; LACTATE DEHYDROGENASE; LUNG; LUNG NEOPLASMS; PEPTIDYL-DIPEPTIDASE A; PERFUSION, REGIONAL; PNEUMONECTOMY; TIME FACTORS;

EID: 0023870245     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/1097-0142(19880401)61:7<1320::AID-CNCR2820610708>3.0.CO;2-J     Document Type: Article

References (7)

1. Isolated lung perfusion with doxorubicin: A preclinical study
2. The pharmacokinetics of doxorubicin in isolated lung of dog and man perfused in vivo
3. Isolated total lung perfusion: Long‐term studies in animals
4. Adriamycin: A new effective agent in the therapy of disseminated sarcoma
5. The uptake and metabolism of doxorubicin in isolated perfused rat lung
6. Plasma pharmacokinetics of Adriamycin and its metabolites in humans with normal hepatic and renal function
7. Clinical effects and pharmacokinetics of different dosage schedules of Adriamycin