Ha-ras restriction fragment length polymorphisms in colorectal cancer

British Journal of Cancer

Volumn 57, Issue 2, 1988, Pages 135-138

  Wyllie, F S ^a   Wynford Thomas, V ^a   Lemoine, N R ^a   Williams, G T ^a   Williams, E D ^a   Wynford Thomas, D ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COLORECTAL CANCER; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; ONCOGENE H RAS;

ALLELES; CHROMOSOME MAPPING; COLONIC NEOPLASMS; COMPARATIVE STUDY; DNA; ELECTROPHORESIS, AGAR GEL; GENE FREQUENCY; GENES, RAS; HUMAN; LEUKOCYTES; POLYMORPHISM (GENETICS); POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RECTAL NEOPLASMS; SUPPORT, NON-U.S. GOV'T;

EID: 0023869882     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.1988.28     Document Type: Article

References (27)

1. ARMITAGE, P. (1971). Statistical Methods in Medical Research. Blackwell: Oxford.
2. BALMAIN, A. (1985). Transforming ras oncogenes and multistage carcinogenesis. Br. J. Cancer, 51, 1.
3. BOS, J.L., FEARON, E.R., HAMILTON, S.R. & 4 others (1987). Prevalence of ras gene mutations in human colorectal cancers. Nature, 327, 293.
4. CAPON, D.J., CHEN, E.Y., LEVINSON, A.D., SEEBURG, P.H. & GOEDDEL, D.V. (1983). Complete nucleotide sequence of the T24 human bladder carcinoma oncogene and its normal homologue. Nature, 302, 33.
5. CHANG, E.H., FURTH, M.E., SCOLNICK, E.M. & LOWY, D.R. (1982). Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus. Nature, 297, 479.
6. DUKES, C.E. (1949). The surgical pathology of rectal cancer. J. Clin. Pathol., 2, 95.
7. FEINBERG, A.P. & VOGELSTIEN, B. (1983). A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem., 132, 6.
8. FORRESTER, K., ALMOGUERA, C., HAN, K., GRIZZLE, W.E. & PERUCHO, M. (1987). Detection of high incidence of K-ras oncogenes during human colon tumorigenesis. Nature, 327, 298.
9. GALLICK, G.E., KURZROCK, R., KLOETZER, W.S., ARLINGHAM, R.B. & GUTTERMAN, J.V. (1985). Expression of p2lras in fresh primary and metastatic human colorectal tumours. Proc. Natl Acad. Sci. USA, 82, 1795.
10. GERHARD, D.S., DRACOPOLI, N.C., BALE, S.J. & 5 others (1987). Evidence against Ha-ras-1 involvement in sporadic and familial melanoma. Nature, 325, 73.
11. GOLDFARB, M., SHIMIZU, K., PERUCHO, M. & WIGLER, M. (1982). Isolation and preliminary characterisation of a human transforming gene from T24 bladder carcinoma cells. Nature, 296, 404.
12. HEIGHWAY, J., THATCHER, N., CERNY, T. & HASLETON, P.S. (1986). Genetic predisposition to human lung cancer. Br. J. Cancer, 53, 453.
13. KRONTIRIS, T.G., DI MARTINO, N.A., COLB, M. & PARKINSON, D.R. (1985). Unique allelic restriction fragments of the human Ha-ras locus in leucocyte and tumour DNAs of cancer patients. Nature, 313, 369.
14. KRONTIRIS, T.G., DI MARTINO, N.A., COLB, M., MICHESON, D. & PARKINSON, D.R. (1986). Human restriction fragment length polymorphisms and cancer risk assessment. J. Cell Biochem., 30, 319.
15. KUNKEL, L.M., SMITH, K.D., BOYER, S.H. & 6 others (1977). Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants. Proc. Natl Acad. Sci. USA., 74, 1245.
16. KURZROCK, R., GALLICK, G.E. & GUTTERMAN, J.U. (1986). Differential expression of p21 ras gene products among histological subtypes of fresh primary human lung tumours. Cancer Res., 46, 1530.
17. LEDER, P., BATTEY, J., LENOIR, G. & 5 others (1983). Translocations among antibody genes in human cancer. Science, 222, 765.
18. LIDERAU, R., ESCOT, C., THEILLET, C. & 4 others (1986). High frequency of rare alleles of the human c-Ha-ras-l proto-oncogene in breast cancer patients. J. Natl Cancer Inst., 77, 697.
19. LOVETT, E. (1976). Family studies in cancer of the colon and rectum. Br. J. Surg., 63, 13.
20. MARSHALL, C.J. (1986). The ras gene family. In Oncogenes and Growth Control, Kahn, P. & Graf, T. (eds) p. 192. Springer- Verlag: Berlin.
21. OHUCHI, N., THOR, A., PAGE, D.L., HORAN HAND, P., HALTER, S.A. & SCHLOM, J. (1986). Expression of the 21, 000 molecular weight ras protein in a spectrum of benign and malignant human mammary tissues. Cancer Res., 46, 2511.
22. PULCIANI, S., SANTOS, E., LAUVER, A.V., LONG, L.K. & BARBACID, M. (1982). Transforming genes in human tumours. J. Cell Biochem., 20, 51.
23. SEEBURG, P.H., COLBY, W.W., CAPON, D.J., GOEDDEL, D.V. & LEVINSON, A.D. (1984). Biological properties of human c-Ha-ras- 1 genes mutated at codon 12. Nature, 312, 71.
24. SPANDIDOS, D.A. & KERR, I.B. (1984). Elevated expression of the human ras oncogene family in premalignant and malignant tumours of the colorectum. Br. J. Cancer, 49, 681.
25. SPANDIDOS, D.A. & WILKIE, N.M. (1984). Malignant transformation of early passage rodent cells by a single mutated human oncogene. Nature, 310, 469.
26. THEIN, S.L., OSCIER, D.G., FLINT, J. & WAINSCOAT, J.S. (1986). Ha-ras hypervariable alleles in myelodysplasia. Nature, 321, 84.
27. THOR, A., HORAN HAND, P., WUNDERLICH, D., CARUSO, A., MURARO, R. & SCHLOM, J. (1984). Monoclonal antibodies define differential ras gene expression in malignant and benign colonic diseases. Nature, 311, 562.