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Volumn 45, Issue 1, 1988, Pages 71-76

Central D2-Dopamine Receptor Occupancy in Schizophrenic Patients Treated With Antipsychotic Drugs

Author keywords

[No Author keywords available]

Indexed keywords

CLOZAPINE; DOPAMINE 2 RECEPTOR; HALOPERIDOL; NEUROLEPTIC AGENT; SULPIRIDE;

EID: 0023853769     PISSN: 0003990X     EISSN: 15383636     Source Type: Journal    
DOI: 10.1001/archpsyc.1988.01800250087012     Document Type: Article
Times cited : (572)

References (40)
  • 1
    • 0013319410 scopus 로고
    • Caracteristiques psycho-physioloques des medicaments neuroleptiques
    • in Garattini S, Ghetti V (eds) Amsterdam, Elsevier Science Publishers
    • Delay J, Deniker O: Caracteristiques psycho-physioloques des medicaments neuroleptiques, in Garattini S, Ghetti V (eds): The Psychotropic Drugs. Amsterdam, Elsevier Science Publishers, 1957, pp 485-501.
    • (1957) The Psychotropic Drugs , pp. 485-501
    • Delay, J.1    Deniker, O.2
  • 3
    • 0016492074 scopus 로고
    • A relation between drug concentrations in brain and striatal homovanillic acid levels in chlorpromazine treated rats
    • Wiesel F-A, Alfredsson G, Likwornik V, Sedvall G: A relation between drug concentrations in brain and striatal homovanillic acid levels in chlorpromazine treated rats. Life Sci 1975;16:1145-1156.
    • (1975) Life Sci , vol.16 , pp. 1145-1156
    • Wiesel, F-A.1    Alfredsson, G.2    Likwornik, V.3    Sedvall, G.4
  • 4
    • 0022621321 scopus 로고
    • Plasma level monitoring of antipsychotic drugs: Clinical utility
    • Dahl S: Plasma level monitoring of antipsychotic drugs: Clinical utility. Clin Pharmacokinet 1986;11:36-61.
    • (1986) Clin Pharmacokinet , vol.11 , pp. 36-61
    • Dahl, S.1
  • 5
    • 78651116398 scopus 로고
    • Effect of chlorpromazine or haloperidol on formation of 3-methoxytyramine and normetanephrine in mouse brain
    • Carlsson A, Lindqvist M: Effect of chlorpromazine or haloperidol on formation of 3-methoxytyramine and normetanephrine in mouse brain. Acta Pharmacol Toxicol 1963;20:140-144.
    • (1963) Acta Pharmacol Toxicol , vol.20 , pp. 140-144
    • Carlsson, A.1    Lindqvist, M.2
  • 6
    • 0017853040 scopus 로고
    • Antipsychotic drugs, neurotransmitters, and schizophrenia
    • Carlsson A: Antipsychotic drugs, neurotransmitters, and schizophrenia. Am J Psychiatry 1978;135:164-173.
    • (1978) Am J Psychiatry , vol.135 , pp. 164-173
    • Carlsson, A.1
  • 7
    • 0017255979 scopus 로고
    • Dopamine receptor binding clinical and pharmacological potencies of antischizophrenic drugs
    • Creese I, Burt DR, Snyder SH: Dopamine receptor binding clinical and pharmacological potencies of antischizophrenic drugs. Science 1976;192:481-483.
    • (1976) Science , vol.192 , pp. 481-483
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 8
    • 0017068246 scopus 로고
    • Antipsychotic drug doses and neuroleptic/dopamine receptors
    • Seeman P, Lee T, Chau-Wong M, Wong K: Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature 1976;261:717-719.
    • (1976) Nature , vol.261 , pp. 717-719
    • Seeman, P.1    Lee, T.2    Chau-Wong, M.3    Wong, K.4
  • 9
    • 0019174607 scopus 로고
    • Relationship of neuroleptic drug effects at brain dopamine, serotonin, adrenergic and histamine receptors to clinical potency
    • Peroutka SJ, Snyder SH: Relationship of neuroleptic drug effects at brain dopamine, serotonin, adrenergic and histamine receptors to clinical potency. Am J Psychiatry 1980;137:1518-1522.
    • (1980) Am J Psychiatry , vol.137 , pp. 1518-1522
    • Peroutka, S.J.1    Snyder, S.H.2
  • 11
    • 84886640129 scopus 로고
    • In vivo quantitative imaging of dopamine receptors in human brain using positron emission tomography and (76Br) bromospiperone
    • Maziere B, Loc'h C, Baron J-C, Sgouropoulos P, Duquesnoy N, D'Antona R, Cambon H: In vivo quantitative imaging of dopamine receptors in human brain using positron emission tomography and (76Br) bromospiperone. Eur J Pharmacol 1985;114:276-272.
    • (1985) Eur J Pharmacol , vol.114 , pp. 272-276
    • Maziere, B.1    Loc'h, C.2    Baron, J-C.3    Sgouropoulos, P.4    Duquesnoy, N.5    D'Antona, R.6    Cambon, H.7
  • 12
    • 0343816773 scopus 로고
    • Quantitative PET-scan determination of dopamine-D2 receptor binding in schizophrenic patients treated with distinct classes of antipsychotic drugs
    • in Shagass C (ed)
    • Farde L, Wiesel F-A, Ehrin E, Hall H, Sedvall G: Quantitative PET-scan determination of dopamine-D2 receptor binding in schizophrenic patients treated with distinct classes of antipsychotic drugs, in Shagass C (ed): Biol Psychiatry 1985;7:363-365.
    • (1985) Biol Psychiatry , vol.7 , pp. 363-365
    • Farde, L.1    Wiesel, F-A.2    Ehrin, E.3    Hall, H.4    Sedvall, G.5
  • 13
    • 0022595579 scopus 로고
    • Quantitative analysis of dopamine-D2 receptor binding in the living human brain by positron emission tomography
    • Farde L, Hall H, Ehrin E, Sedvall G: Quantitative analysis of dopamine-D2 receptor binding in the living human brain by positron emission tomography. Science 1986;231:258-261.
    • (1986) Science , vol.231 , pp. 258-261
    • Farde, L.1    Hall, H.2    Ehrin, E.3    Sedvall, G.4
  • 14
    • 0023029468 scopus 로고
    • Imaging of neurotransmitter receptors in the living human brain
    • Sedvall G, Farde L, Persson A, Wiesel F-A: Imaging of neurotransmitter receptors in the living human brain. Arch Gen Psychiatry 1986;43:995-1005.
    • (1986) Arch Gen Psychiatry , vol.43 , pp. 995-1005
    • Sedvall, G.1    Farde, L.2    Persson, A.3    Wiesel, F-A.4
  • 15
    • 0013277610 scopus 로고
    • Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography
    • Farde L, Ehrin E, Eriksson L, Greitz TY, Hall H, Hedström CG, Litton JE, Sedvall G: Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography. Proc Natl Acad Sci USA 1985;82:3863-3867.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 3863-3867
    • Farde, L.1    Ehrin, E.2    Eriksson, L.3    Greitz, T.Y.4    Hall, H.5    Hedström, C.G.6    Litton, J.E.7    Sedvall, G.8
  • 17
    • 84935767269 scopus 로고
    • Head fixation device for reproducible positron alignment in transmission CT and positron emission tomography
    • Bergström M, Boethius J, Eriksson L, Greitz T, Ribbe T, Widen L: Head fixation device for reproducible positron alignment in transmission CT and positron emission tomography. J Comput Assist Tomogr 1981;8:74-87.
    • (1981) J Comput Assist Tomogr , vol.8 , pp. 74-87
    • Bergström, M.1    Boethius, J.2    Eriksson, L.3    Greitz, T.4    Ribbe, T.5    Widen, L.6
  • 18
    • 0015861774 scopus 로고
    • Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50% inhibition (IC 50) of an enzymatic reaction
    • Cheng Y, Prusoff W: Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50% inhibition (IC 50) of an enzymatic reaction. Biochem Pharmacol 1973;22:3099-3108.
    • (1973) Biochem Pharmacol , vol.22 , pp. 3099-3108
    • Cheng, Y.1    Prusoff, W.2
  • 19
    • 0018729368 scopus 로고
    • Quantitative analysis of sulpiride in body fluids by high performance liquid chromatography with fluorescence detection
    • Alfredsson G, Sedvall G, Wiesel F-A: Quantitative analysis of sulpiride in body fluids by high performance liquid chromatography with fluorescence detection. J Chromatogr 1979;164:187-193.
    • (1979) J Chromatogr , vol.164 , pp. 187-193
    • Alfredsson, G.1    Sedvall, G.2    Wiesel, F-A.3
  • 20
    • 0021003185 scopus 로고
    • A high-performance liquid chromatographic method for the determination of haloperidol and reduced haloperidol in serum
    • Larsson M, Forsman A, Öhman R: A high-performance liquid chromatographic method for the determination of haloperidol and reduced haloperidol in serum. Curr Ther Res 1985;34:999-1008.
    • (1985) Curr Ther Res , vol.34 , pp. 999-1008
    • Larsson, M.1    Forsman, A.2    Öhman, R.3
  • 21
    • 0001232987 scopus 로고
    • Receptors for antipsychotic drugs
    • Leysen J: Receptors for antipsychotic drugs. Adv Hum Psychopharmacol. 1983;3:62-84.
    • (1983) Adv Hum Psychopharmacol , vol.3 , pp. 62-84
    • Leysen, J.1
  • 22
    • 0018647462 scopus 로고
    • The substituted benzamides: A novel class of dopamine antagonists
    • Jenner P, Marsden CD: The substituted benzamides: A novel class of dopamine antagonists. Life Sci 1979;25:479-486.
    • (1979) Life Sci , vol.25 , pp. 479-486
    • Jenner, P.1    Marsden, C.D.2
  • 23
    • 84915137270 scopus 로고
    • Interaction of substituted benzamide drugs with cerebral dopamine receptors
    • in Ackenheil M, Matussek N (eds) Paris, Expansion Scientific Francaise
    • Jenner P, Testa B, van de Waterbeem H, Marsden CD: Interaction of substituted benzamide drugs with cerebral dopamine receptors, in Ackenheil M, Matussek N (eds): Special Aspects of Psychopharmacology. Paris, Expansion Scientific Francaise, 1983, pp 153-170.
    • (1983) Special Aspects of Psychopharmacology , pp. 153-170
    • Jenner, P.1    Testa, B.2    van de Waterbeem, H.3    Marsden, C.D.4
  • 24
    • 0021844076 scopus 로고
    • Specific in vitro and in vivo binding of 3H-raclopride: A potent substituted benzamide drug with high affinity for dopamine D2 receptors in the rat brain
    • Köhler C, Hall H, Ögren S-O, Gawell L: Specific in vitro and in vivo binding of 3H-raclopride: A potent substituted benzamide drug with high affinity for dopamine D2 receptors in the rat brain. Biochem Pharmacol 1985;34:2251-2259.
    • (1985) Biochem Pharmacol , vol.34 , pp. 2251-2259
    • Köhler, C.1    Hall, H.2    Ögren, S-O.3    Gawell, L.4
  • 25
    • 0018908452 scopus 로고
    • Dopamine-mediated behaviour and 3H-spiperone binding to striatal membranes in rats after nine months' haloperidol administration
    • Owen F, Cross AJ, Waddington JL: Dopamine-mediated behaviour and 3H-spiperone binding to striatal membranes in rats after nine months' haloperidol administration. Life Sci 1980;26:55-59.
    • (1980) Life Sci , vol.26 , pp. 55-59
    • Owen, F.1    Cross, A.J.2    Waddington, J.L.3
  • 26
    • 0017599705 scopus 로고
    • Antischizophrenic drugs: Chronic treatment elevated dopamine receptor binding in brain
    • Burt DR, Creese I, Snyder SH: Antischizophrenic drugs: Chronic treatment elevated dopamine receptor binding in brain. Science 1977;196:326-328.
    • (1977) Science , vol.196 , pp. 326-328
    • Burt, D.R.1    Creese, I.2    Snyder, S.H.3
  • 27
    • 0018908307 scopus 로고
    • Changes in rat striatal dopamine turnover and receptor activity during one year's neuroleptic administration
    • Clow A, Theodorou A, Jenner P: Changes in rat striatal dopamine turnover and receptor activity during one year's neuroleptic administration. Eur J Pharmacol 1980;63:135-144.
    • (1980) Eur J Pharmacol , vol.63 , pp. 135-144
    • Clow, A.1    Theodorou, A.2    Jenner, P.3
  • 29
    • 0001427177 scopus 로고
    • Kritische Stellungsnahme zum Begriff der Neuroleptika (anhand von pharmakologischen und klinischen Befunden mit Clozapin)
    • Stille G, Hippius H: Kritische Stellungsnahme zum Begriff der Neuroleptika (anhand von pharmakologischen und klinischen Befunden mit Clozapin). Pharmacopsychiatry 1971;4:182-191.
    • (1971) Pharmacopsychiatry , vol.4 , pp. 182-191
    • Stille, G.1    Hippius, H.2
  • 30
    • 0020512496 scopus 로고
    • Antipsychotic drug action: Clinical, biochemical, and pharmacological evidence for site specificity of action
    • Borison RL, Hitri A, Blowers AJ, Diamond BI: Antipsychotic drug action: Clinical, biochemical, and pharmacological evidence for site specificity of action. Clin Neuropharmacol 1983;6:137-150.
    • (1983) Clin Neuropharmacol , vol.6 , pp. 137-150
    • Borison, R.L.1    Hitri, A.2    Blowers, A.J.3    Diamond, B.I.4
  • 33
    • 0000870544 scopus 로고
    • Die Kinetik der Invertinwirkung
    • Michaelis L, Menten ML: Die Kinetik der Invertinwirkung. Biochem Z 1913;49:1333.
    • (1913) Biochem Z , vol.49 , pp. 1333
    • Michaelis, L.1    Menten, M.L.2
  • 36
    • 0017850496 scopus 로고
    • Clinical effects and drug concentrations in plasma and cerebrospinal fluid in psychotic patients treated with fixed doses of chlorpromazine
    • Wode-Helgodt B, Borg S, Fyrö B, Sedvall G: Clinical effects and drug concentrations in plasma and cerebrospinal fluid in psychotic patients treated with fixed doses of chlorpromazine. Acta Psychiatr Scand 1978;58:149-173.
    • (1978) Acta Psychiatr Scand , vol.58 , pp. 149-173
    • Wode-Helgodt, B.1    Borg, S.2    Fyrö, B.3    Sedvall, G.4
  • 37
    • 0019155756 scopus 로고
    • What is the best maintenance dose of neuroleptics in schizophrenia?
    • Baldessarini RJ, Davis JM: What is the best maintenance dose of neuroleptics in schizophrenia? Psychiatry Res 1980;3:115-122.
    • (1980) Psychiatry Res , vol.3 , pp. 115-122
    • Baldessarini, R.J.1    Davis, J.M.2
  • 38
    • 0021363872 scopus 로고
    • Relationships between drug concentrations in serum and CSF, clinical effects and monoaminergic variables in schizophrenic patients treated with sulpiride or chlorpromazine
    • Alfredsson G, Bjerkenstedt L, Edman G, Härnryd C, Oxenstierna G, Sedvall G, Wiesel F-A: Relationships between drug concentrations in serum and CSF, clinical effects and monoaminergic variables in schizophrenic patients treated with sulpiride or chlorpromazine. Acta Psychiatr Scand 1984;69(suppl 311):49-74.
    • (1984) Acta Psychiatr Scand , vol.69 , pp. 49-74
    • Alfredsson, G.1    Bjerkenstedt, L.2    Edman, G.3    Härnryd, C.4    Oxenstierna, G.5    Sedvall, G.6    Wiesel, F-A.7
  • 40
    • 0022254616 scopus 로고
    • Absence of relationship of serum haloperidol concentration and clinical response in chronic schizophrenia: A fixed-dose study
    • Bigelow LB, Kirch DG, Braun T, Korpi ED, Wagner RL, Zalcman S, Wyatt RJ: Absence of relationship of serum haloperidol concentration and clinical response in chronic schizophrenia: A fixed-dose study. Psychopharmacol Bull 1985;21:66-68.
    • (1985) Psychopharmacol Bull , vol.21 , pp. 66-68
    • Bigelow, L.B.1    Kirch, D.G.2    Braun, T.3    Korpi, E.D.4    Wagner, R.L.5    Zalcman, S.6    Wyatt, R.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.