Relationships between the activity of some H2-receptor agonists of histamine and their ab initio molecular electrostatic potential (MEP) and electron density comparison coefficients

European Journal of Medicinal Chemistry

Volumn 23, Issue 1, 1988, Pages 7-10

  Luque, F J ^a   Sanz, F ^a   Illas, F ^b   Pouplana, R ^b   Smeyers, Y G ^c  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c INSTITUTO DE ESTRUCTURA DE LA MATERIA   (Spain)

Author keywords

activity prediction; histamine H2 receptor agonist; molecular electrostatic potential (MEP)

Indexed keywords

HISTAMINE; HISTAMINE DERIVATIVE;

NONHUMAN; PHARMACODYNAMICS; STRUCTURE ACTIVITY RELATION; THEORETICAL STUDY;

EID: 0023848399     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/0223-5234(88)90160-2     Document Type: Article

References (13)

1. Theoretical study of some H2-receptor agonists of histamine. The H2-essential conformation of histamine
2. QSAR and Strategies in the Design of Bioactive Compounds
3. Quantum chemical study of the molecular patterns of MAO inhibitors and substrates