Differential effects of exercise intensity on serum uric acid concentration

Medicine and Science in Sports and Exercise

Volumn 20, Issue 1, 1988, Pages 55-59

  Green, Howard J ^a   Fraser, Ian G ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

Author keywords

Exercise; Serum creatine kinase; Serum uric acid

Indexed keywords

CREATINE KINASE;

ADULT; EXERCISE; HUMAN; HUMAN EXPERIMENT; MALE; MUSCLE METABOLISM; NORMAL HUMAN; TRAINING; URIC ACID BLOOD LEVEL; WORKLOAD;

ADULT; CREATINE KINASE; EXERTION; HUMAN; INOSINE MONOPHOSPHATE; MALE; MUSCLES; PHYSICAL EDUCATION AND TRAINING; PHYSICAL ENDURANCE; SUPPORT, NON-U.S. GOV'T; URIC ACID;

EID: 0023845198     PISSN: 01959131     EISSN: 15300315     Source Type: Journal    
DOI: 10.1249/00005768-198802000-00008     Document Type: Article

References (37)

1. APPLE, F. S. Presence of creatine kinase MB isoenzyme during marathon training. N. Engl. J. Med. 305:764-765, 1981.
2. BADIT, P., S. M. MATHEWS, and M. J. RENNIE. Changes in blood ammonia, lactate and amino acids in relation to work load during bicycle exercise. Eur. J. Appi. Physiol. 50:405-411, 1983.
3. BANISTER, E. W., M. E. ALLEN, I. B. MEKJAVIC, A. K. SINGH, B. LEGGE, and B. J. C. MUTCH. Time course of ammonia and lactate accumulation in blood during bicycle exercise. Eur. J. Appi. Physiol. 51:195-202, 1983.
4. Boss, G. R. Hyperuricemia and gout. N. Engl. J. Med. 300:1459-1468, 1979.
5. Dudley, G. A., R. S. Staron, T. F. Murray, F. G. Hagerman, and A. LUGJNBUHL. Muscle fibre composition and blood ammonia levels after intense exercise in humans. Med Appl. Phvsioi: Respir. Environ. Exerc. Physiol. 54:582-586, 1983.
6. Fox, I. H., M. L. HALPERIN, M. B. GOLDSTEIN, et al. Renal excretion of uric acid during prolonged fasting. Metabolism 5:551-559, 1976.
7. GALHO, H. Hormonal and Metabolic Adaptation to Exercise. NY: George Thieme Vcrlag, 1983, pp. 1-116.
8. GOLLNICK, P. D., R. B. ARMSTRONG, C. W. SEMISROWICH, IV, W. L. SHEPHERD, and B. SALTIN. Glycogen depletion patterns in human skeletal muscle fibres during prolonged work. Pflüwers Arch. 344:1-12, 1973.
9. GOLLNICK, P. D., K. PIEIIL, and B. SALTIN. Selective glycogen depiction pattern in human muscle fibers after exercise of varying intensity and at varying pedal rates. J. Physiol. 241:45-57, 1974.
10. GREEN, H. J., M. E. HOUSTON, J. A. THOMSON, J. R. SUTTON, and P. D. GOLLNICK. Metabolic consequences of supramaximal arm work performed during prolonged submaximal leg work. J. Appl. Physiol.: Respir. Environ. Exerc. Physiol. 46:247-255, 1979.
11. GREEN, H. J., J. A. THOMSON, M. E. BALL, R. L. HUGIISON, M. E. HOUSTON, and M. T. SHARRATT. Alterations in blood volume following short-term supramaximal exercise. J. Appl. Physiol.: Rcspiral. Environ. Exerc. Physiol. 56:145-149, 1984.
12. GREEN, H. J., R. L. HUGHSON, J. A. THOMSON, and M. T. SHARRATT. Supramaximal exercise following after induced hypervolemia. I. Gas exchange and acid-base balance. J. Appl. Physiol. 62:1944-1953, 1987.
13. GREEN, H. J., J. A. THOMSON, and M. E. HOUSTON. Supramaximal exercise after training induced hypervolemia. 11. Blood and muscle substrates and metabolites. J. Appl. Physiol. 62:1954-1961, 1987.
14. GREEN, H. J., L. L. JONES, R. L. HUGIISON, D. C. PAINTER, and B. W. FARRANCE. Exercise induced hypervolemia: lack of an effect on oxygen utilization during exercise. Med. Sci. Sports Exerc. 19:202-206, 1987.
15. GOODMAN, M. and J. LOWENSTEIN. The purine nucleotide cycle. J. Biol. Chem. 252:5054-5060, 1977.
16. HUMPHREY, S. M., D. G. HOLLISS, and R. N. SELYE. Myocardial adenine pool depiction and recovery of mechanical function following ischacmia. Am. J. Physiol. 245(Heart Circ. Physiol. 17):H644-H651, 1985.
17. RAMAN, R. L., B. GOIIEEN, R. PALTON, and P. RAVEN. The effects of near maximal exercise on serum enzymes: the exercise profile versus the cardiac profile. Clin. Chem. Ada 81:145-152, 1977.
18. KNOCHEL, J. P., L. N. DOTIN, and R. J. HAMIIURGER. Heat stress, exercise and muscle injury. Effects of urate metabolism and renal function. Ann. Intern. Med. 81:321-328, 1974.
19. KNOCHEL, J. P. and N. W. CARTER. The role of muscle cell injury in the pathogenesis of acute renal failure after exercise. Kidney Intern. 10:558-564, 1976.
20. MEYER, R. A. and R. L. TERJUNG. Ammonia and IMP in different skeletal muscle. Am. J. Physiol. 239(Cell Physiol. 8):C32-C38, 1980.
21. MEYER, R. A., G. A. DUDLEY, and R. L. TERJUNG. Ammonia and IMP in different skeletal muscle fibers after exercise in rats. J. Appl. Phvsiol.: Respirat. Environ. Exerc. Physiol. 49:1033-1041, 1980.
22. NASRALLAH, S. and V. KHALADI. Nature of purines excreted in urine during muscular exercise. J. Appl. Phvsiol. 19:246-248, 1964.
23. NEWIIAM, D. J., D. A. JONES, and R. H. T. EDWARDS. Plasma creatine kinase changes after eccentric and concentric contractions. Muscle and Nerve 9:59-61, 1986.
24. NICHOLS, J., A. T. MILLER, and E. P. HIATT. Influence of muscular exercise in uric acid excretion in man. J. Appl. Phvsiol. 3:501-507,1950-51.
25. O'MALLEY, B. P., T. J. DAVIES, and F. D. ROSENTHAL. Effects of rest, exercise and warming on serum creatine kinase levels in primary hypothyroidism. Clin. Sci. 60:595-597, 1981.
26. PATTERSON, B. P., K. K. KAISER, and M. H. BROOKE. Forearm exercise increases plasma hypoxanthine. J. Neurol. Neurosurg. Psychiat. 45:552-553, 1982.
27. Pette, D. Metabolic differentiation of distinct muscle types at the level of enzymatic organization. In: Muscle Metabolism during exercise, B. Pernow and B. Saltin (Eds.). NY: Plenum Press, 1971, pp. 33-50.
28. POORTMANS, J. R. Exercise and renal function. J. Sports Med. 1:125-153, 1984.
29. ROUGIER, C. and J. P. BAHIN. A blood and urine study of heavy muscular work on ureic and uric metabolism in man. J. Sports Med. 15:212-222, 1975.
30. SADINA, R. L., J. L. SWAIN, B. M. PATTEN, T. ASHIZAWA, W. E. O'BRIEN, and E. W. HOLMES. Disruption of the purine nucleotide cycle. A potential explanation for muscle dysfunction in myoad-enylate deaminase deficiency. J. Clin. Invest. 66:1419-1423, 1980.
31. SAIILIN, K., G. PALMSKOG, and E. HULTMAN. Adenine nucleotide and IMP contents of the quadriceps muscle in man after exercise. PJlugers Arch. 374:193-198, 1978.
32. SALTIN, B. and B. ESSEN. Muscle glycogen, lactate, ATP and CP in intermittent exercise. In: Muscle during Exercise, B. Pernow and B. Saltin (Eds.). NY: Plenum Press, 1971, pp. 419-424.
33. SANDERS, T. M. and C. M. BLOOR. Effects of repeated endurance exercise on serum enzyme activities in well conditioned males. Med. Sci. Sports 7:44-47, 1975.
34. SENAY, I. C, D. MITCHELL, and C. II. WYNDIIAM. Acclimation to a hot humid environment: body fluid adjustments. J. Appl. Physiol. 40:786-796, 1976.
35. SUTTON, J. R., C. J. Touws, G. R. WARD, and L. H. Fox. Purine metabolism during strenuous muscular exercise in man. Metabolism 29:254-259, 1980.
36. SZASZ, G., W. GRUHER, and E. BERNT. Creatine kinase in serum. I. Determination of optimum reaction conditions. Clin. Chem. 22:650-656, 1976.
37. THOMSON, J. A., H. J. GREEN, and M. E. HOUSTON. Muscle glycogen depletion patterns in fast twitch fibre subgroups of man during submaximal and supramaximal exercise. Pflügers Arch. 379:105-108, 1979.