The effect of protamine sulfate on platelet function

Scandinavian Cardiovascular Journal

Volumn 22, Issue 1, 1988, Pages 55-59

  Lindblad, Bengt ^a   Wakefield, Thomas W ^a   Whitehouse, Walter M ^a   Stanley, James C ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Cell membrane; Platelets; Protamine; Thrombin

Indexed keywords

HEPARIN; PROTAMINE SULFATE;

ANIMAL EXPERIMENT; DOG; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; LEUKOPENIA; NONHUMAN; PULMONARY HYPERTENSION; THROMBOCYTE; THROMBOCYTOPENIA;

ANIMAL; BLOOD PLATELETS; BLOOD PRESSURE; DOGS; PLATELET ADHESIVENESS; PLATELET AGGREGATION; PLATELET COUNT; PROTAMINES; SUPPORT, U.S. GOV'T, NON-P.H.S.; THROMBOCYTOPENIA;

EID: 0023841501     PISSN: 14017431     EISSN: None     Source Type: Journal    
DOI: 10.3109/14017438809106052     Document Type: Article

References (13)

1. Studies on hemolytic properties of protamine
2. Complement activation during cardiopulmonary bypass by heparin–protamine interaction
3. Aggregation of blood platelets by adenosine diphosphate and its reversal
4. Effect of glycosaminoglycans and antithrombin III on uptake and inhibition of thrombin by the vascular wall
5. On the mechanism of platelet aggregation induced by heparin, protamine and polybrene
6. Protamine: a review of its toxicity
7. A study of the toxicity of the protamine salmine
8. Protamine-antagonist to heparin
9. Sequestration of platelets in the pulmonary circulation as a consequence of protamine reversal of the anticoagulant effect of heparin
10. Protamine pretreatment attenuation of hemodynamic and hematologic effects of heparin–protamine interaction: a prospective randomized study in humans undergoing aortic reconstructive surgery
11. Attenuation of hemodynamic and hematologic effects of heparin–protamine sulfate interaction in a canine model
12. Failure of complement depletion to attenuate hemodynamic and hematologic responses induced by heparin–protamine reactions
13. Depressed cardiovascular function and altered platelet kinetics following protamine sulfate reversal of heparin activity