Human platelet alpha granules contain a nonspecific inhibitor of megakaryocyte colony formation: Its relationship to type β transforming growth factor (TGF‐β)

Journal of Cellular Physiology

Volumn 134, Issue 1, 1988, Pages 93-100

  Mitjavila, M T ^a   Vinci, G ^a   Villeval, J L ^a   Kieffer, N ^a   Henri, A ^a   Testa, U ^a,b   Breton Gorius J ^a   Vainchenker, W ^a  

^a INSERM   (France)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

ALPHA GRANULE; COLONY FORMING UNIT MK; CONTROLLED STUDY; HUMAN; HUMAN CELL; INHIBITION; THROMBOCYTE;

BLOOD PHYSIOLOGY; BLOOD PLATELETS; CELL DIVISION; CYTOPLASMIC GRANULES; ERYTHROPOIESIS; HUMAN; MEGAKARYOCYTES; PEPTIDES; STEM CELLS; SUPPORT, NON-U.S. GOV'T; TISSUE EXTRACTS; TRANSFORMING GROWTH FACTORS;

EID: 0023839231     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.1041340111     Document Type: Article

References (47)

1. Type β transforming growth factor in human platelets: Release during platelet degranulation and action on vascular smooth muscle cells
2. Transforming growth factor β in human platelets. Identification of a major storage site, purification and characterization
3. Lactoferrin acts on Ia‐like antigen positive subpopulations of human monocytes to inhibit production of colony stimulating activity in vitro
4. Biomolecule‐cell interactions and the regulation of myelopoiesis
5. The identification of leukemia‐associated inhibitory activity (LIA) as acidic isoferritins. A regulatory role for acidic isoferritins in the production of granulocytes and macrophages
6. Stimulation and inhibition by normal human serum of colony formation in vitro by bone marrow cells
7. Serum contains a platelet‐derived transforming growth factor
8. Gray platelet syndrome: Immunoelectron microscopic localization of fibrinogen and von Willebrand factor in platelets and megakaryocytes
9. A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors
10. Production of erythroid‐potentiating activity by a human T lymphoblast cell line
11. Biochemical studies of two patients with the gray platelet syndrome, a selective deficiency of platelet alpha granules
12. Assay of an activity in the serum of patients with disorders of thrombopoiesis that stimulates formation of megakaryocyte colonies
13. Purification of kidney epithelial cell growth inhihitors
14. Biologic properties of homogenous interleukin 3. I. Demonstration of WEHI‐3 growth factor activity, mast cell growth factor activity, P cell‐stimulating activity and histamine‐producing cell stimulating activity
15. Complete replacement of serum in primary cultures of erythropoietin dependent red cell precursors (CFU‐E) by albumin, transferrin, iron, unsaturated fatty acid, lecithin and cholesterol
16. Type β transforming growth factor is a potent direct inhibitor of murine megakaryocytopoiesis in vitro
17. Transforming growth factor β is an important immunomodulatory protein for human β lymphocytes
18. Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth
19. Human megakaryocytic progenitors (CFU‐M) assaying in methylcellulose. Physical characteristics and requirements for growth
20. Megakaryopoiesis in vitro of patients with essential thrombocythaemia: Effect of plasma and serum on megakaryocytic colony formation
21. Humoral control of thrombopoiesis
22. Type β transforming growth factor is an inhibitor of myogenic differentiation
23. The molecular biology and functions of the granulocyte‐macrophage colony‐stimulating factors
24. Transforming growth factor production by chemically transformed cells
25. Specific protein and glycoprotein deficiencies in platelets isolated from two patients with the gray platelet syndrome
26. β‐Transforming growth factor is stored in human blood platelets as a latent high molecular weight complex
27. The effect of interleukin‐3 and GM‐CSA‐2 on megakaryocyte and myeloid clonal colony formation
28. Gray platelet syndrome: A variety of qualitative platelet disorder
29. New class of transforming growth factors potentiated by epidermal growth factor: Isolation from non‐neoplastic tissues
30. Type β transforming growth factor: A bifunctional regulator of cellular growth
31. Effects of transforming growth factor β on the functions of natural killer cells: Depressed cytolytic activity and blunting of inteferon responsiveness
32. Detection of thrombopoietic activity in plasma by stimulation of suppressed thrombopoiesis
33. Characterization of human megakaryocytic colony formation in human plasma
34. The effect of type β transforming growth factor (TGF‐β) on human megakaryocytic colony formation in vitro
35. Polypeptide transforming growth factor isolated from bovine sources and used for wound healing “in vivo”
36. Transforming growth factor‐β: Biological function and chemical structure
37. Monoclonal antibodies against human glycoprotein IIIa
38. Normal human serum contains a factor(s) capable of inhibiting megakaryocyte colony formation
39. Two monoclonal antiplatelet antibodies as markers of human megakaryocyte maturation: Immunofluorescent staining and platelet peroxidase detection in megakaryocyte colonies and in vivo cells from normal and leukemic patients
40. In vitro inhibition of human megakaryocyte colony formation by platelets
41. Coordinate control of 3T3 cell proliferation by platelet‐derived growth factor and plasma components
42. Purification and biochemical characterization of human pluripotent hematopoietic colony‐stimulating factor
43. Two factor requirement for murine megakaryocyte colony formation
44. Murine megakaryocyte colony stimulating factor: Its relationship to interleukin 3
45. “Panning” for lymphocytes: A method for cell selection
46. Human IL‐3 (multi‐CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL‐3