Variability in drug susceptibility amongst clones and isolates of Plasmodium falciparum

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 82, Issue 1, 1988, Pages 33-36

  Thaithong, S ^a   Beale, G H ^b   Chutmongkonkul, M ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; CHLOROQUINE; MEFLOQUINE; PYRIMETHAMINE; QUININE; SULFADOXINE;

CELL CULTURE; DRUG THERAPY; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; PROTOZOON; STRAIN DIFFERENCE; THAILAND;

ANIMAL; ANTIMALARIALS; CLONE CELLS; DRUG RESISTANCE; PLASMODIUM FALCIPARUM; SUPPORT, NON-U.S. GOV'T; TIME FACTORS;

EID: 0023839182     PISSN: 00359203     EISSN: 18783503     Source Type: Journal    
DOI: 10.1016/0035-9203(88)90253-2     Document Type: Article

References (19)

1. Bruce-Chwatt, L.J. (editor) (1986). Chemotherapy of Malaria (2nd edition). Geneva: World Health Organization, pp. 1-261.
2. Carter, R. (1978). Studies on enzyme variation in the murine malaria parasites Plasmodium berghei, P. vinckei and P. chabaudii by starch gel electrophoresis. Parasitology, 76, 241-267.
3. Carter, R. & McGregor, I. A. (1973). Enzyme variation in Plasmodium falciparum in the Gambia. Transactions of the Royal Society of Tropical Medicine and Hygiene, 67, 830-837.
4. Desjardins, R. E., Canfield, C. J., Haynes, D. M. & Chulay, J. D. (1979). Quantitative assessment of antimalaria activity in vitro by a semi-automated microdilution technique. Antimicrobial Agents and Chemotherapy, 16, 710-718.
5. Fenton, B., Walker, A. & Walliker, D. (1985). Protein variation in clones of Plasmodium falciparum detected by two-dimensional electrophoresis. Molecular and Biochemical Parasitology, 16, 173-183.
6. McBride, J. S., Newbold, C. I. & Anand, R. (1985). Polymorphism of a high molecular weight schizont antigen of the human malaria parasite Plasmodium falciparum. Journal of Experimental Medicine, 161, 160-180.
7. Nguyen-Dinh, P., Payne, D., Teklehaimanot, A., Zevallos-Ipenza, A., Day, M. M. & Duverseau, Y. T. (1985). Development of an in vitro microtest for determining the susceptibility of Plasmodium falciparum to sulfadoxine-pyrimethamine: laboratory investigations and field studies in Port-au-Prince, Haiti. Bulletin of the World Health Organization, 63, 585-592.
8. Padua, R. A. (1981). Plasmodium chabaudi: genetics of resistance to chloroquine. Experimental Parasitology, 52, 419-426.
9. Pinswasdi, C, Thaithong, S., Beale, G. H., Fenton, B., Webster, H. K. & Payanand, K. (1987). Polymorphism of proteins in malaria parasites following mefloquine treatment. Molecular and Biochemical Parasitology (in press).
10. Rosario, V. (1981). Cloning of naturally occurring mixed infections of malaria parasites. Science, 212, 1037-1038.
11. Sanderson, A., Walliker, D. & Molez, J. F. (1981). Enzyme typing of Plasmodium falciparum from some African and other old world countries. Transactions of the Royal Society of Tropical Medicine and Hygiene, 75, 263-267.
12. Spencer, H. C, Watkins, W. M., Sixsmith, D. G., Koech, D. K. & Chulay, J. D. (1984). A new in vitro test for pyrimethamine/sulphadoxine susceptibility of Plasmodium falciparum and its correlation with in vivo resistance in Kenya. Bulletin of the World Health Organization, 62, 615-621.
13. Thaithong, S. (1983). Clones of different sensitivities in drug-resistant isolates of Plasmodium falciparum. Bulletin of the World Health Organization, 61, 709-712.
14. Thaithong, S., Sueblinwong, T. & Beale, G. H. (1981). Enzyme typing of some isolates of Plasmodium falciparum from Thailand. Transactions of the Royal Society of Tropical Medicine and Hygiene, 75, 268-270.
15. Thaithong, S., Beale, G. H. & Chutmongkonkul, M. (1983). Susceptibility of Plasmodium falciparum to five drugs: an in vitro study of isolates mainly from Thailand. Transactions of the Royal Society of Tropical Medicine and Hygiene, 77, 228-231.
16. Thaithong, S., Beale, G. H., Fenton, B., McBride, J., Rosario, V., Walker, A. & Walliker, D. (1984). Clonal diversity in a single isolate of the malaria parasite Plasmodium falciparum. Transactions of the Royal Society of Tropical Medicine and Hygiene, 78, 242-245.
17. Thaithong, S., Suebsang, L., Rooney, W. & Beale, G. H. (1988). Evidence of increased chloroquine sensitivity in Thai isolates of Plasmodium falciparum. Transactions of the Royal Society of Tropical Medicine and Hygiene, 82, 000-000.
18. Trager, W. & Jensen, J. B. (1976). Human malaria parasites in continuous culture. Science, 193, 674-675.
19. Webster, H. K., Thaithong, S., Pavanand, K., Yong-vanitchit, K., Pinswasdi, C. & Boudreau, E. F. (1985). Cloning of mefloquine resistant Plasmodium falciparum from Thailand. American Journal of Tropical Medicine and Hygiene, 34, 1022-1027.