Natural History of Pancreatic Islet B‐Cell Function in Type 2 Diabetes Mellitus Studied over Six Years by Homeostasis Model Assessment

Diabetic Medicine

Volumn 5, Issue 1, 1988, Pages 36-41

  Rudenski, A S ^a   Hadden, D R ^b   Atkinson, A B ^b   Kennedy, L ^b   Matthews, D R ^a   Merrett, J D ^b   Pockaj, B ^a   Turner, R C ^a  

^a RADCLIFFE INFIRMARY   (United Kingdom)

^b ROYAL VICTORIA HOSPITAL   (United Kingdom)

Author keywords

Insulin sensitivity; Islet B cell function; Type 2 diabetes

Indexed keywords

BODY WEIGHT; DIET; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MATHEMATICAL MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; ORGANIZATION AND MANAGEMENT; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ADULT; AGED; DIABETES MELLITUS, NON-INSULIN-DEPENDENT; FEMALE; HOMEOSTASIS; HUMAN; ISLETS OF LANGERHANS; MALE; MIDDLE AGE; MODELS, BIOLOGICAL; REGRESSION ANALYSIS; SUPPORT, NON-U.S. GOV'T;

EID: 0023838643     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/j.1464-5491.1988.tb00938.x     Document Type: Article

References (14)

1. Insulin deficiency and insulin resistance interaction in diabetes: estimation of their relative contribution by feedback analysis from basal plasma insulin and glucose concentrations
2. Homeostasis model assessment: insulin resistance and β‐cell function from fasting plasma glucose and insulin concentrations in man
3. Natural history of diabetes presenting age 40–69 years: a prospective study of the influence of intensive dietary therapy
4. Society of Actuaries
5. Dietary management of maturity onset diabetes
6. Insulin treatment reverses the insulin resistance of Type II diabetes mellitus
7. Decreased sensitivity of the pancreatic beta cells to glucose in prediabetic and diabetic subjects. A glucose dose‐response study
8. Risk factors for worsening diabetes in subjects with impaired glucose tolerance
9. Aspects of the pathogenesis of type 2 diabetes
10. Beta‐cell dysfunction, rather than insulin insensitivity, is the primary defect in familial type 2 diabetes
11. Insulin secretion and insulin action in non‐insulin‐dependent diabetes mellitus: which defect is primary?
12. Insulin resistance and impaired insulin secretion in subjects with histories of gestational diabetes mellitus
13. Insulin resistance: a common feature of diabetes mellitus
14. Predicting the need for insulin therapy in late onset (40–69 years) diabetes mellitus