Kinetics of Long-Chain (Sphingoid) Base Biosynthesis in Intact LM Cells: Effects of Varying the Extracellular Concentrations of Serine and Fatty Acid Precursors of This Pathway

Biochemistry

Volumn 27, Issue 1, 1988, Pages 340-345

  Merrill, Alfred H ^a   Wang, Elaine ^a   Mullins, Richard E ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PALMITOYL COENZYME A; SERINE; SPHINGANINE;

2 AMINO 1 HYDROXY 3 OCTADECANONE; CELL CULTURE; LM CELL; MOUSE; NONHUMAN; SERINE PALMITOYLTRANSFERASE; SPHINGENINE;

ACYLTRANSFERASES; ANIMAL; BIOLOGICAL TRANSPORT; CARBON RADIOISOTOPES; CELLS, CULTURED; KINETICS; MICE; PALMITIC ACID; PALMITIC ACIDS; PALMITOYL COENZYME A; SERINE; SPHINGOLIPIDS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023836942     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00401a051     Document Type: Article

References (36)

1. Bjerve, K. S. (1985) Biochem. Biophys. Acta 833, 396–405.
2. Braun, P. E., & Snell, E. E. (1968) J. Biol. Chem. 243, 3775–3783.
3. Braun, P. E., Morell, P., & Radin, N. S. (1970) J. Biol. Chem. 245, 335–341.
4. Chatterjee, S., Clarke, K. S., & Kwiterovich, P. O., Jr. (1986) J. Biol. Chem. 261, 13474–13479.
5. Cleland, W. W. (1970) Enzymes (3rd Ed.) 2, 1–65.
6. Di Mari, S. J., Brady, R. N., & Snell, E. E. (1971) Arch. Biochem. Biophys. 143, 553–565.
7. Englesberg, E., Bass, R., & Heiser, W. (1976) Somatic Cell Genet. 2, 411–428.
8. Gaver, R. C., & Sweeley, C. C. (1965) J. Am. Oil Chem. Soc. 42, 295–298.
9. Hammond, R. K., & Sweeley, C. C. (1973) J. Biol. Chem. 248, 632–640.
10. Hannun, Y. A., Loomis, C. R., Merrill, A. H., Jr., & Bell, R. M. (1986) J. Biol. Chem. 261, 12604–12609.
11. Karlsson, K. A. (1970) Chem. Phys. Lipids 5, 6–43.
12. Kishimoto, Y. (1983) Enzymes (3rd Ed.) 16, 357–407.
13. Kulmacz, R. J., & Schroepfer, G. J., Jr. (1978) Biochem. Biophys. Res. Commun. 82, 371–377.
14. Kurtz, D. J., & Kanfer, J. N. (1973) J. Neurochem. 20, 963–968.
15. Lev, M., & Milford, A. F. (1981) Arch. Biochem. Biophys. 212, 424–431.
16. Merrill, A. H., Jr. (1983) Biochim. Biophys. Acta 754, 284–291.
17. Merrill, A. H., Jr., & Wang, E. (1986) J. Biol. Chem. 261, 3764–3769.
18. Merrill, A. H., Jr., Nixon, D. W., & Williams, R. D. (1985) J. Lipid Res. 26, 617–622.
19. A., Bell, R. M., & Kinkade, J. M., Jr. (1986a) J. Biol. Chem. 261, 12610–12615.
20. Merrill, A. H., Jr., Wang, E., & Wertz, P. W. (1986b) Lipids 21, 529–530.
21. Messmer, T. O., & Merrill, A. H., Jr. (1986) Fed. Proc., Fed. Am. Soc. Exp. Biol. 45, 4001.
22. Palmieri, R., & Klingenberg, M. (1979) Methods Enzymol. 56, 279–301.
23. Radin, N. S. (1984) J. Liqid Res. 25, 1536–1540.
24. Remesy, C., Fafournoux, P., & Demigne, C. (1983) J. Nutr. 113, 28–39.
25. Snell, E. E., Dimari, S. J., & Brady, R. N. (1970) Chem. Phys. Lipids 5, 6–43.
26. Soltysiak, R. M., Matsuura, F., Bloomer, D., & Sweeley, C. C. (1984) Biochim. Biophys. Acta 792, 214–226.
27. Stevens, V. L., Tribble, D. L., & Lambeth, J. D. (1985) Arch. Biochem. Biophys. 242, 324–327.
28. Sundaram, K. S., & Lev, M. (1985) J. Lipid Res. 26, 473–477.
29. Tanaka, T., Hosaka, K., Hoshimaru, M., & Numa, S. (1979) Eur. J. Biochem. 98, 165–172.
30. Vega, A., & Nunn, P. B. (1969) Anal. Biochem. 32, 446–453.
31. Verdery, R. B., Ill, & Theolis, R., Jr. (1982) J. Biol. Chem. 257, 1412–1417.
32. Williams, R. D., Nixon, D. W., & Merrill, A. H., Jr. (1984a) Cancer Res. 44, 1918–1923.
33. Williams, R. D., Wang, E., & Merrill, A. H., Jr. (1984b) Arch. Biochem. Biophys. 228, 282–291.
34. Wilson, E., Olcott, M. C., Bell, R. M., Merrill, A. H., & Lambeth, J. D. (1986) J. Biol. Chem. 261, 12616–12623.
35. Yogeeswaran, G., Murray, R. K., Pearson, M. L., Sanwal, B. D., McMorris, F. A., & Ruddle, F. H. (1973) J. Biol. Chem. 248, 1231–1239.
36. Yohe, H. C., Roarke, D. E., & Rosenberg, A. (1976) J. Biol. Chem. 251, 7083–7087.