Kidney synthesizes less metallothionein than liver in response to cadmium chloride and cadmium-metallothionein

Toxicology and Applied Pharmacology

Volumn 92, Issue 1, 1988, Pages 95-102

  Sendelbach, Louis E ^a   Klaassen, Curtis D ^a  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; METALLOTHIONEIN;

ANIMAL EXPERIMENT; CADMIUM METALLOTHIONEIN; KIDNEY; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ANIMAL; CADMIUM; CADMIUM CHLORIDE; DACTINOMYCIN; KIDNEY; LIVER; MALE; METALLOTHIONEIN; MICE; RATS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023835083     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/0041-008X(88)90231-1     Document Type: Article

References (35)

1. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
2. A radioimmunoassay for human metallothionein
3. Induction of renal metallothionein synthesis by parenteral cadmium-thionein in rats
4. Studies on toxicity of metallothionein in rat kidney epithelial cell culture
5. Cadmium-metallothionein induced nephropathy
6. Gastrointestinal absorption and organ distribution of oral cadmium chloride and cadmium-metallothionein in mice
7. Metabolism of intravenously injected cadmium-binding protein
8. Cadmium-induced hepatic and renal injury in chronically exposed rats: Likely role of cadmium-met-allothionein in nephrotoxicity
9. Dose-response effects of various metal ions on rat liver metallothionein, glutathione, heme oxygenase, and cytochrome P-450
10. Evaluation of the Cd/hemoglobin affinity assay for the rapid determination of metallothionein in biological tissues
11. Renal transport of cadmium-metallothionein
12. Tolerance to cadmium-induced hepatotoxicity following cadmium pretreatment
13. Zinc-induced tolerance to cadmium hepatotoxicity
14. On the proposed role of metallothionein in the transport of cadmium
15. Toxicity and distribution of cadmium administered to rats at sublethal doses
16. Dosage-dependent disposition of cadmium administered orally to rats
17. Distribution of cadmium after oral administration of cadmium-thionein to mice
18. Reabsorption of filtered cadmium-metallothionein in the rabbit kidney
19. Cadmium metabolism and toxicity: Experimental studies in mice with special reference to the use of biological materials as indices of retention and the possible role of metallothionein in transport and detoxification of cadmium
20. The induced synthesis of metallothionein in various tissues of rat in response to metals. I. Effect of repeated injection of cadmium salts
21. A simplified method for determination of metallothionein in animal tissues
22. Mercury binding in the kidney and liver of rats repeatedly exposed to mercuric chloride: Induction of metallothionein by mercury and cadmium
23. Relative nephrotoxic properties of chlorinated methane, ethane, and ethylene derivatives in mice
24. Binding of cadmium metallothionein to isolated renal brush border membranes
25. Metallothionein in the extracellular fluids as an index of cadmium toxicity
26. Renal metabolism and toxicity of metallothionein
27. Cadmium-metallothionein nephropathy: Relationships between ultrastructure/biochemical alterations and intracellular cadmium binding
28. Early cellular effects of circulating cadmium-thionein in kidney proximal tubules
29. Rat kidney metallothionein induced by injection of cadmium-thionein: Changes of chromatographic properties with time and their relation to copper content and kidney dysfunction
30. 109Cd-labeled metallothionein in rats
31. Concentration of metallothionein in major organs of rats after administration of various metals
32. Toxicology of cadmium-thionein
33. The metallothioneins
34. Cadmium-thionein and the nephrotoxicity of cadmium