Identification of collagen fibrils in scleroderma skin

Journal of Investigative Dermatology

Volumn 90, Issue 1, 1988, Pages 48-54

  Perlish, Jerome S ^a   Lemlich, Gabrielle ^a   Fleischmajer, Raul ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN FIBRIL; FIBRONECTIN; PROCOLLAGEN;

ELECTROPHORESIS; HISTOCHEMISTRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; SCLERODERMA; SKIN BIOPSY; ULTRASTRUCTURE;

EID: 0023829880     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12462561     Document Type: Article

References (27)

1. LeRoy E.C. Increased collagen synthesis by scleroderma fibroblasts in vitro . A possible defect in the regulation or activation of the scleroderma fibroblast J Clin Invest 54 1974 880 889
2. Buckingham R.B. Prince R.K. Rodnan G.P. Taylor F. Increased collagen accumulation in dermal fibroblast cultures from patients with progressive systemic sclerosis (scleroderma) J Lab Clin Med 92 1978 5 21
3. Uitto J. Bauer E.A. Eisen A.Z. Scleroderma: increase in biosynthesis of triple helical type I and type III procollagen associated with unaltered expression of collagenase by skin fibroblasts in culture J Clin Invest 64 1979 921 930
4. Fleischmajer R. Perlish J.S. Krieg T. Timpl R. Variability in collagen and fibronectin synthesis by scleroderma fibroblasts in primary culture J Invest Dermatol 76 1981 400 403
5. Perlish J.S. Bashey R.I. Stephens R.E. Fleischmajer R. Connective tissue synthesis by cultured fibroblasts. I. In vitro collagen synthesis by normal and scleroderma dermal fibroblasts Arthritis Rheum 19 1976 891 901
6. Krieg T. Perlish J. Fleischmajer R. Braun-Falco O. Collagen synthesis in scleroderma: selection of fibroblast populations during subcultures Arch Dermatol Res 277 1985 373 376
7. Cooper S.W. Keyser A.J. Beaulieu A.D. Ruoslahti E. Nimni M.E. Quismorio F.P. Jr Increase in fibonectin in the deep dermis of involved skin in progressive systemic sclerosis Arthritis Rheum 22 1979 983 987
8. Fleischmajer R. Dessau W. Timpl R. Krieg T. Luderschmidt C. Wiestner M. Immunofluorescence analysis of collagen, fibronectin, and basement membrane protein in scleroderma skin J Invest Dermatol 75 1980 270 275
9. Fleischmajer R. Timpl R. Tuderman L. Raisher L. Wiestner M. Perlish J.S. Graves P.N. Ultrastructural identification of extension amino propeptides of type I and III collagen in human skin Proc Natl Acad Sci USA 78 1981 7360 7364
10. Yamada K.M. Olden K. Fibronectins – Adhesive glycoproteins of cell surface and blood Nature (Lond) 275 1978 179 184
11. Vaheri A. Mosher D.F. High molecular weight, cell surface-associated glycoprotein (fibronectin) lost in malignant transformation Biochim Biophys Acta 516 1978 1 25
12. Braun-Falco O. Rubec M. Collagen fibrils of the scleroderma in ultrathin skin sections Nature (Lond) 202 1964 708 709
13. Hayes R.L. Rodnan G.P. The ultrastructure of skin in progressive systemic sclerosis (scleroderma). I. Dermal collagen fibers Am J Pathol 63 1971 433 442
14. Fleischmajer R. Damiano V. Nedwich A. Scleroderma and the subcutaneous tissue Science (Wash DC) 171 1971 1019 1021
15. Fleischmajer R. Gay S. Meigel W.N. Perlish J.S. Collagen in the cellular and fibrotic stages of scleroderma Arthritis Rheum 21 1978 418 428
16. Fleischmajer R. Gay S. Perlish J.S. Cesarini J.P. Immunoelectron microscopy of type III collagen in normal and scleroderma skin J Invest Dermatol 75 1980 189 191
17. Nowack H. Gay S. Wick G. Becker U. Timpl R. Preparation and use in immunohistology of antibodies specific for type I and type III collagen and procollagen J Immunol Methods 12 1976 117 124
18. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature (Lond) 227 1970 680 685
19. Towbin H. Staehelin T. Gordon J. Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets: procedure and some applications Proc Natl Acad Sci USA 76 1979 4350 4354
20. Rennard S.I. Berg R. Martin G.R. Foidart J.M. Robez P.G. Enzymelinked immunoassay (ELISA) for connective tissue components Anal Biochem 104 1980 205 214
21. Fleischmajer R. Olsen B. Timpl R. Perlish J.S. Lovelace O. Collagen fibril formation during embryogenesis Proc Natl Acad Sci USA 80 1983 3354 3358
22. Keene D.R. Sakai L.Y. Bachinger H.P. Burgeson R.E. Type III collagen is present on banded collagen fibrils regardless of fibril diameter, J Cell Biol
23. Fleischmajer R. Perlish J.S. Timpl R. Collagen fibrillogenesis in human skin Ann NY Acad Sci 460 1985 246 257
24. Wick G. Kraft D. Kokoschka E.M. Timpl R. The diagnostic application of specific anti-procollagen sera. I. Analysis of skin biopsies Clin Immunol Immunopathol 6 1976 182 191
25. Meigel W.N. Gay S. Weber L. Dermal architecture and collagen type distribution Arch Dermatol Res 259 1977 11 19
26. Vaheri A. Kurkinen M. Lehto V.P. Linder E. Timpl R. Codistribution of pericellular matrix proteins in cultured fibroblasts and loss in transformation: fibronectin and procollagen Proc Natl Acad Sci USA 75 1978 4944 4948
27. Fleischmajer R. Timpl R. Ultrastructural localization of fibronectin to different anatomic structures of human skin J Histochem Cytochem 32 1984 315 321