Effects of intrathecal administration of neuropeptides on a spinal nociceptive reflex in the rat: VIP, galanin, CGRP, TRH, somatostatin and angiotensin II

Neuropeptides

Volumn 11, Issue 1, 1988, Pages 23-32

  Cridland, R A ^a   Henry, J L ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; CALCITONIN GENE RELATED PEPTIDE; GALANIN; NEUROPEPTIDE; PEPTIDE; PROTIRELIN; SOMATOSTATIN; VASOACTIVE INTESTINAL POLYPEPTIDE; SUBSTANCE P;

ANIMAL; ARTICLE; DRUG EFFECT; INTRASPINAL DRUG ADMINISTRATION; MALE; NOCICEPTIVE RECEPTOR; PAIN ASSESSMENT; RAT; RAT STRAIN; TAIL; VOCALIZATION; ANIMAL EXPERIMENT; INTRATHECAL DRUG ADMINISTRATION; NOCICEPTION; NONHUMAN; SPINAL REFLEX; TAIL FLICK TEST;

ANGIOTENSIN II; ANIMAL; CALCITONIN GENE-RELATED PEPTIDE; GALANIN; INJECTIONS, SPINAL; MALE; NEUROPEPTIDES; NOCICEPTORS; PAIN MEASUREMENT; PEPTIDES; PROTIRELIN; RATS; RATS, INBRED STRAINS; SOMATOSTATIN; SUPPORT, NON-U.S. GOV'T; TAIL; VASOACTIVE INTESTINAL PEPTIDE; VOCALIZATION, ANIMAL;

EID: 0023818868     PISSN: 01434179     EISSN: None     Source Type: Journal    
DOI: 10.1016/0143-4179(88)90024-8     Document Type: Article

References (54)

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2. Endorphins mediate overshoot of substance P-induced facilitation of a spinal nociceptive reflex
3. Substance P analogue blocks SP-induced facilitation of a spinal nociceptive reflex
4. Substance P reduced tail-flick latency: implication for chronic pain syndromes
5. A VIP-containing system concentrated in the lumbosacral region of human spinal cord
6. Immunoreactive vasoactive intestinal polypeptide is concentrated in the sacral spinal cord: a possible marker for pelvic visceral afferent fibers
7. Distribution of galanin immunoreactivity in the central nervous system and the responses of galanin-containing neuronal pathways to injury
8. Demonstration of thyrotropin-releasing hormone immunoreactivity in neurons of the mouse spinal dorsal horn
9. Calcitonin gene-related peptide (CGRP) in capsaicin-sensitive substance P immunoreactive sensory neurons in animals and man: distribution and release by capsaicin
10. Vasoactive intestinal polypeptide (VIP)-containing neurons in the spinal cord of the rat and their projections
11. Immunohistochemical evidence for the existence of angiotensin II-containing nerve terminals in the brain and spinal cord in the rat
12. The distribution and origin of VIP in the spinal cord of six mammalian species
13. Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and eight other species
14. The distribution of nine peptides in rat spinal cord with special emphasis on the substantia gelatinosa and on the area around the central canal (lamina X)
15. A thyrotropin-releasing hormone-containing system in the rat dorsal horn separate from serotonin
16. Immunohistochemical evidence for separate populations of somatostatin-containing and substance P-containing primary afferent neurons in the rat
17. Immunohistochemical distribution of somatostatin-like immunoreactivity in the central nervous system of the adult rat
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27. Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat
28. Design for inexpensive unit for measuring tail flick latencies
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31. Convergence of visceral and curaneous input onto spinothalamic tract cells in the thoracic spinal cord of the cat
32. Convergence of cutaneous and pelvic visceral nociceptive inputs onto primate spinothalamic neurons
33. Convergence of visceral and cutaneous afferent pathways in the lumbar spinal cord
34. Inhibitory effects of galanin on the isolated spinal cord of the newborn rat
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37. Effect of substance P in cat dorsal horn neurones activated by noxious stimuli
38. Noxious heating of the skin releases immunoreactive substance P in the substantia gelatinosa of the cat: a study with antibody microprobes
39. Evidence that substance P and somatostatin transmit separate information related to pain in the spinal dorsal horn
40. 7,9)-SP elicits hypoalgesia and motor blockade in the rat and antagonizes noxious responses induced by substance P
41. Effects of intrathecal and intracerebroventricular injections of substance P on nociception in the rat and mouse
42. Hyperalgesia produced by intrathecal substance P and related peptides desensitization and cross desensitization
43. Characterization of the hyperalgesic effect induced by intrathecal injection of substance P
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45. Calcitonin gene-related peptide promotes mechanical nociception by potentiating release of substance P from the spinal dorsal horn in rats
46. Calcitonin gene-related peptide is a potent inhibitor of substance P degradation
47. Intrathecal somatostatin modulates spinal sensory and reflex mechanisms; behavioral and electrophysiological studies in the rat
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51. Thyrotropin-releasing hormone and amphetamine produce different patterns of behavioral excitation in rats
52. Differential motor and blood pressure effects of intrathecal oxytocin and TRH in the rat
53. Spinal cord pharmacology of adrenergic agonist-mediated antinociception