Prevention of atherosclerotic progression in Watanabe rabbits by probucol

The American Journal of Cardiology

Volumn 62, Issue 3, 1988, Pages

  Kita, Toru ^a   Nagano, Yutaka ^a   Yokode, Masayuki ^a   Ishii, Kenji ^a   Kume, Noriaki ^a   Narumiya, Shuh ^a   Kawai, Chuichi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LOW DENSITY LIPOPROTEIN; PROBUCOL;

ANIMAL EXPERIMENT; AORTA ATHEROSCLEROSIS; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RABBIT; ULTRASTRUCTURE;

ANIMAL; ARTERIOSCLEROSIS; CELLS, CULTURED; COMPARATIVE STUDY; DRUG EVALUATION, PRECLINICAL; FEMALE; FOAM CELLS; HYPERLIPIDEMIA; LIPID PEROXIDES; LIPOPROTEINS; MALE; MICE; MICE, INBRED STRAINS; OXIDATION-REDUCTION; PHENOLS; PROBUCOL; RABBITS; SUPPORT, NON-U.S. GOV'T;

EID: 0023802468     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(88)80045-6     Document Type: Article

References (36)

1. The LDL receptor locus and the genetics of familial hypercholesterolemia
2. Defective lipoprotein receptors and atherosclerosis: lessons from an animal counterpart of familial hypercholesterolemia
3. A receptor-mediated pathway for cholesterol homeostasis
4. Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit). Incidence and development of atherosclerosis and xanthoma
5. Deficiency of low density lipoprotein receptors in liver and adrenal gland of the WHHL rabbit, an animal model of familial hypercholesterolemia
6. Cellular pathology of progressive atherosclerosis in the WHHL rabbit. An animal model of familial hypercholesterolemia
7. Purification and cultivation of monocytes and macrophages
8. Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins
9. Metabolism of cationized lipoproteins by human fibroblasts. Biochemical and morphologic correlations
10. Stimulation of cholesteryl ester synthesis in mouse peritoneal macrophages by cholesterol-rich very low density lipoproteins from the Watanabe heritable hyperlipidemic rabbit, an animal model of familial hypercholesterolemia
11. Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia
12. Impaired receptor-mediated catabolism of low density lipoproteins in fasted rabbits
13. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
14. Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts
15. Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinct from the low density lipoprotein receptor
16. High-performance aqueous gel permeation chromatography of serum lipoproteins: selective detection of cholesterol by enzymatic reaction
17. Use of Toyopearl as a support for the immobilization of urease
18. Electrophoretic separation of plasma lipoprotein in agarose gel
19. Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture
20. A simple fluorometric assay for lipoperoxide in blood plasma
21. Rapid extraction of arachidonic acid metabolites from biological samples using octadecylsilyl silica
22. 2 and related enzymes in postmortem human brain
23. 4 from human polymorphonuclear leukocytes as determined by radioimmunoassay
24. Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins
25. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
26. Delayed clearance of very low density and intermediate density lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits
27. The pathogenesis of atherosclerosis—An update
28. Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis
29. Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids
30. Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidation
31. Stimulated arachidonate metabolism during foam cell transformation of mouse peritoneal macrophages with oxidized low density lipoprotein
32. Prostacyclin and thromboxane A2 biosynthesis capacities of heart, arteries and platelets at various stages of experimental atherosclerosis in rabbits
33. Membrane perturbation and stimulation of arachidonic acid metabolism
34. Leukotrienes and the cardiovascular system
35. Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia
36. Effects of probucol on xanthomata regression in familial hypercholesterolemia