Synthesis, Conformation, and Immunosuppressive Activity of A Conformationally Restricted Cyclosporine Lactam Analogue

Journal of Medicinal Chemistry

Volumn 31, Issue 9, 1988, Pages 1805-1815

  Aebi, Johannes D ^a   Guillaume, Dominique ^a   Dunlap, Brian E ^a   Rich, Daniel H ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; CYCLOSPORIN A DERIVATIVE; CYCLOSPORIN A[3,4 LACTAM]; IMMUNOSUPPRESSIVE AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; CELL CULTURE; CELL GROWTH; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; THYMOCYTE;

ANIMAL; CHEMISTRY; COMPARATIVE STUDY; CONCANAVALIN A; CYCLOSPORINS; HYDROGEN BONDING; IMMUNOSUPPRESSION; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR CONFORMATION; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES; TEMPERATURE;

EID: 0023785950     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00117a022     Document Type: Article

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