The “lost autoregulation hypothesis” and brain lesions in the newborn —an update—

Brain and Development

Volumn 10, Issue 3, 1988, Pages 143-146

  Lou, Hans C ^a  

^a JOHN F KENNEDY INSTITUTE   (Denmark)

Author keywords

Autoregulation of cerebral blood flow; cerebral ischemia; perinatal asphyxia; periventricular hemorrhage; periventricular leukomalacia

Indexed keywords

ANIMAL MODEL; AUTOREGULATION; BIRTH; BIRTH INJURY; BLOOD PRESSURE; BRAIN BLOOD FLOW; BRAIN HEMORRHAGE; BRAIN INJURY; BRAIN ISCHEMIA; ELECTROENCEPHALOGRAPHY; HUMAN; HYPOTENSION; LEUKOMALACIA; NEWBORN HYPOXIA; NONHUMAN; PRIORITY JOURNAL; SHEEP;

EID: 0023783444     PISSN: 03877604     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0387-7604(88)80016-0     Document Type: Review

References (30)

1. Impaired autoregulation of cerebral blood flow in the distressed newborn infant
2. Low cerebral blood flow: a risk factor in the neonate
3. Is arterial hypertension crucial for the development of intraventricular haemorrhage in the neonate?
4. Perinatal hypoxic-ischemic brain damage and intraventricular hemorrhage. A pathogenetic model
5. Arterial oxygenation determines autoregulation of cerebral blood flow in fetal lamb
6. Impairment of cerebral blood flow autoregulation in the newborn lamb by hypoxia
7. Effects of arterial carbon dioxide tension and oxygen saturation on CBF autoregulation in dogs
8. Pathogenesis and evolution of periventricular leukomalacia
9. Origin of intraventricular haemorrhage in the preterm infant
10. Etiological factors associated with the development of periventricular leukomalacia
11. Perinatal events which precede periventricular haemorrhage and leukomalacia in the newborn
12. Observations on the control of cerebral blood flow in the sheep fetus and newborn lamb
13. Pathophysiology of perinatal hypoxic-ischemic brain damage
14. Clinical events relating to intraventricular haemorrhage in the new- born
15. Perinatal hypoxic-ischemia brain injury
16. Direct monitoring of arterial blood pressure in depressed and normal newborn infants during the first hour of life
17. Neonatal blood pressures
18. Elevations in arterial blood pressure during motor activity and epileptic seizures in the newborn
19. Mean arterial blood pressure and neonatal cerebral lesions
20. Restoration of autoregulation of cerebral blood flow by hypocapnia
21. 2 changes, and visual evoked potentials in mechanically ventilated, preterm infants
22. May hypocarbia cause ischae-mic brain damage in the preterm infant?
23. Nuclear magnetic resonance and brain metabolism in birth asphyxiated babies
24. Aetiological role of cerebral blood-flow alterations in development of peri-intraventricular haemorrhage
25. EEG depression and germinal layer haemorrhage in the newborn
26. Hypertensive peaks in the pathogenesis of intraventricular hemorrhage in the newborn. Abolition by phenobarbitone sedation
27. Fluctuating cerebral blood flow velocity in respiratory distress syndrome