The c-fos protein interacts with c-Jun AP-1 to stimulate transcription of AP-1 responsive genes

Cell

Volumn 54, Issue 4, 1988, Pages 541-552

  Chiu, Robert ^a   Boyle, William J ^a   Meek, Jennifer ^a   Smeal, Tod ^a   Hunter, Tony ^b   Karin, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; CELL CULTURE; DNA TRANSCRIPTION; GENE INTERACTION; MOUSE; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL;

CELL LINE; ENHANCER ELEMENTS (GENETICS); HUMAN; MODELS, GENETIC; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0023782359     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(88)90076-1     Document Type: Article

References (39)

1. 120-tetradecanoyl-phorbol-13-acetate (TPA) induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5′-flanking region
2. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
3. The jun oncogene encodes a sequence-specific trans-activator similar to AP-1
4. Modification of fos proteins: phosphorylation of c-fos but not v-fos, is stimulated by 12-tetradecanoyl-phorbol-13-acetate and serum
5. MATα1 protein, a yeast transcription activator, binds synergistically with a second protein to a set of cell-type-specific genes
6. The molecular genetics of cancer
7. Human proto-oncogene c-jun encodes a DNA-binding protein with structural and functional properties of transcription factor AP-1
8. V-jun encodes a nuclear protein with enhancer binding properties of AP-1
9. Antibodies to the evolutionarily conserved amino-terminal domain of the v-myb protein detect the c-myb protein in widely divergent metazoan species
10. Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters
11. Identification of 39,000 dalton protein in cells transformed by FBJ murine osteosarcoma virus
12. Viral and cellular fos proteins are complexed with a 39,000 dalton cellular protein
13. Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos
14. Analysis of Fos protein complexes and Fos-related antigens by high-resolution two-dimensional gel electrophoresis
15. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
16. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine
17. Transcription factor AP-2 mediates induction by two different signal-transduction pathways protein kinase C and cAMP
18. Phorbol ester induces the transcriptional stimulatory activity of the SV40 enhancer
19. Transcription control by oncogenes
20. Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein
21. Induction of a factor that binds to the polyoma virus A enhancer on differentiation of embryonal carcinoma cells
22. DNA-bound Fos proteins activate transcription in yeast
23. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
24. A new class of yeast transcriptional activators
25. Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes
26. Yeast HAP2 and HAP3 activators both bind to the CYC1 upstream activation site UAS2 in an interdependent manner
27. Discrete elements within the SV40 enhancer region display different cell-specific activities
28. Common DNA-binding site for Fos protein complexes and transcription factor AP-1
29. Analysis of the differentiation-promoting potential of inducible c-fos gene introduced into embryonal carcinoma cells
30. A gene activated by growth factors is related to the oncogene v-jun
31. The Fos protein complex is associated with DNA in isolated nuclei and binds to DNA cellulose
32. The c-erb-A protein is a high-affinity receptor for thyroid hormone
33. Transcriptional activation encoded by the V-fos gene
34. Interactions between a DNA-binding transcription factor (COUP) and a non DNA-binding factor (S300-II)
35. Proto-oncogene fos: complex but versatile regulation
36. Homology between the DNA-binding domain of the GCN4 regulatory protein of yeast and the carboxyl-terminal region of a protein coded for by the oncogene jun
37. The action of oncogenes in the cytoplasm and nucleus
38. The c-erb-A gene encodes a thyroid hormone receptor
39. Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells