Immunohistochemical study of cytochrome P-45011 β-hydroxylase in human adrenal cortex with mineralo- and glucocorticoid excess

Virchows Archiv A Pathological Anatomy and Histopathology

Volumn 413, Issue 4, 1988, Pages 313-318

  Sasano, Hironobu ^a   Okamoto, Mitsuhiro ^b   Sasano, Nobuaki ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Adrenal cortex; Adrenocortical adenoma; Cytochrome P 450; Hypercorticism; Steroid 11 hydroxylase

Indexed keywords

CYTOCHROME P450; MONOCLONAL ANTIBODY; STEROID 11BETA MONOOXYGENASE;

ADRENAL CORTEX; ADRENAL CORTEX CARCINOMA; ANIMAL CELL; CATTLE; HISTOCHEMISTRY; HUMAN; HUMAN CELL; HYPERADRENOCORTICISM; NONHUMAN; PRIORITY JOURNAL; SWINE;

ADENOMA; ADRENAL CORTEX; ADRENAL GLAND NEOPLASMS; ANIMAL; CATTLE; CUSHING SYNDROME; HUMAN; HYPERALDOSTERONISM; HYPERPLASIA; IMMUNOHISTOCHEMISTRY; STEROID 11-BETA-HYDROXYLASE; STEROID HYDROXYLASES; SUPPORT, NON-U.S. GOV'T; SWINE;

EID: 0023778747     PISSN: 01747398     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/BF00783023     Document Type: Article

References (26)

1. Intraadrenal steroid concentration in man: zonal differences and developmental changes
2. Immunogold cytochemistry of cytochrome P-450 in porcine adrenal cortex
3. Light and electron microscopic immunohistochemistry on the localization of cytochrome P-450 of the side chain cleavage system and of cytochrome P-450 and 11 β-hydroxylase in the bovine adrenal cortical cells
4. Regulation of 18-hydroxycorticosterone formation in bovine adrenocortical mitochondria
5. Induction of 11 β-hydroxylase by corticotropin in primary cultures of bovine adrenocortical cells
6. Aldosterone biosynthesis and cytochrome P-45011 β: evidence for two different forms of the enzyme in rats
7. Oxidative reactions in the formation of an aldehyde group in the biosynthesis of aldosterone
8. Cytochrome P-45011 β and P-450scc in adrenal cortex: zonal distribution and intramitochondrial localization by the horseradish peroxidase-labelled antibody method
9. 19-hydroxylation of 18-hydroxy-11-deoxycorticosterone catalyzed by cytochrome P-45011 β of bovine adrenocortex
10. Hyperaldosteronism with low plasma renin (primary aldosteronism)
11. Effect of calmodulin on aldosterone synthesis by a cytochrome P-45011 β-reconstituted system from bovine adrenocortical mitochondria
12. 18, 19-Dihydroxy-deoxycorticosterone; a novel product of cytochrome P-45011 β-catalyzed reaction
13. The natural history of salt-wasting disorders of adrenal and renal origin
14. Functional pathology in adrenal cortex
15. Endocrinologic pathology of functioning adrenocortical tumors
16. Immunohistochemistry of cytochrome P-450 21-hydroxylase: Microscopic examination of the enzyme in the bovine adrenal cortex and kidney
17. Immunohistochemical localization of cytochrome P-450c21 in human adrenal cortex, with respect to endocrine function
18. An endocrine-pathological spectrum of non-tumorous hyperaldosteronism with suppressed plasma renin activity
19. Studies on ACTH action in perfused bovine adrenals: the site of action of ACTH in corticosteroidogenesis
20. Monoclonal antibodies against bovine adrenal cytochrome P-45011 β and cytochrome P-450scc. Their isolation, characterization and application to immunohistochemical analysis of adrenal cortex
21. Aldosterone biosynthesis by a reconstitutes cytochrome P-45011 β system
22. Synthesis of aldosterone by a reconstituted system of cytochrome P-45011 β from bovine adrenocortical mitochondria
23. Cytochrome P-450 for 11 β- and 18-hydroxylase activities of bovine adrenocortical mitochondria: One enzyme or two?
24. Zonal distribution of cytochrome P-450s (P-45011 β and P-450scc) and their relation to steroidogenesis in bovine adrenal cortex
25. The synthesis of aldosterone by the adrenal cortex