Development and evaluation using hairless mouse skin of a transdermal timolol product

International Journal of Pharmaceutics

Volumn 48, Issue 1-3, 1988, Pages 247-254

  O'Neill, Catherine T ^a   Deasy, P B ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Hairless mouse skin; Timolol base; Transdermal delivery

Indexed keywords

AEROSIL; CARBOMER; CARBOXYMETHYLCELLULOSE; ETHYLENE VINYL ACETATE COPOLYMER; PLASTIBASE; POLYACRYLIC ACID; POLYPROPYLENE; SILASTIC; TIMOLOL; UNCLASSIFIED DRUG;

ANIMAL CELL; BLOOD LEVEL; DRUG MONITORING; MOUSE; NONHUMAN; PKA; PRIORITY JOURNAL; SKIN PERMEABILITY; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0023775725     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(88)90269-4     Document Type: Article

References (12)

1. Systematic delivery of timolol after dermal application: transdermal flux and skin irritation potential in the rat and dog
2. Transdermal therapeutic systems
3. Permeation of hairless mouse skin 1: Experimental methods and comparison with human epidermal permeation by alkanols
4. Transdermal drug delivery: the ground rules are emerging
5. Interpretation and prediction of the kinetics of transdermal drug delivery: oestradiol, hycoscine and timolol
6. Clinical pharmacokinetics of beta-adrenoceptor blocking drugs
7. Mechanisms of transdermal controlled nitroglycerin administration (1): development of a finite-dosing skin permeation system
8. Membrane systems
9. Effect of topical vehicle composition on the in vitro release of fluocinoloone acetonide and its acetate ester
10. The permeation behavior of several membranes with potential use in the design of transdermal devices
11. Initial evaluation of transdermal timolol: serum concentrations and β-blockade