Synthesis and evaluation of multisubstrate inhibitors of an oncogene-encoded tyrosine-specific protein kinase. 2

Journal of Medicinal Chemistry

Volumn 31, Issue 9, 1988, Pages 1768-1772

  Kruse, Carolyn H ^a   Holden, Kenneth G ^a   Offen, Priscilla H ^a   Pritchard, M Lynn ^a   Feild, John A ^a   Rieman, David J ^a   Bender, Paul E ^a   Ferguson, Blair ^a   Greig, Russell G ^a   Poste, George ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5' (4 FLUOROSULFONYLBENZOYL)ADENOSINE; 5' [4 (BENZYLAMINOSULFONYL)BENZOYL]ADENOSINE; ADENOSINE DERIVATIVE; PROTEIN SERINE KINASE; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG; P1 ADENOSINE 5' P3 PHENYL TRIPHOSPHATE; P1 ADENOSINE 5' P3 PHENYL TRIPHOSPHATE DERIVATIVE; P1 ADENOSINE 5' P4 PHENYL TETRAPHOSPHATE;

DRUG SPECIFICITY; DRUG SYNTHESIS; ENZYME INHIBITION; GENE EXPRESSION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ABELSON MURINE LEUKEMIA VIRUS; ADENOSINE; ADENOSINE TRIPHOSPHATE; BINDING SITES; CHEMISTRY; COMPARATIVE STUDY; ESCHERICHIA COLI; KINETICS; ONCOGENES; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASE; RECOMBINANT PROTEINS; TYROSINE; AMIDES; PHOSPHORIC ACIDS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0023772228     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm00117a016     Document Type: Article

References (16)