Structure-activity analysis of a class of orally active hydroxamic acid inhibitors of leukotriene biosynthesis

Journal of Medicinal Chemistry

Volumn 31, Issue 10, 1988, Pages 1960-1964

  Summers, James B ^a   Gunn, Bruce P ^a   Martin, Jonathan G ^a   Martin, Michael B ^a   Mazdiyasni, Hormoz ^a   Stewart, Andrew O ^a   Young, Patrick R ^a   Bouska, Jennifer B ^a   Goetze, Andrew M ^a   Dyer, Richard D ^a   Brooks, Dee W ^a   Carter, George W ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; HYDROXAMIC ACID DERIVATIVE; LEUKOTRIENE;

ANAPHYLAXIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; BIOAVAILABILITY; BLOOD LEVEL; DRUG HALF LIFE; DRUG METABOLISM; DRUG SYNTHESIS; INTRAVENOUS DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; RAT; SHEEP; STRUCTURE ACTIVITY RELATION;

EID: 0023764488     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00118a016     Document Type: Article

References (12)

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