Oral toxicity of a bloom of the cyanobacterium microcystis aeruginosa administered to mice over periods up to 1 year

Journal of Toxicology and Environmental Health

Volumn 24, Issue 3, 1988, Pages 291-305

  Falconer, Ian R ^a   Smith, Judy V ^a   Jackson, Alan R B ^b   Jones, Angela ^a   Runnegar, Maria T C ^a  

^a UNIVERSITY OF NEW ENGLAND   (Australia)

^b NSW AGRICULTURE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOIDOSIS; ANIMAL EXPERIMENT; AUTOPSY; CARCINOGENICITY; CYANOBACTERIUM; FEMALE; HISTOLOGY; HISTOPATHOLOGY; MALE; MICROCYSTIS AERUGINOSA; MORTALITY; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; SEX DIFFERENCE;

ADMINISTRATION, ORAL; ANIMAL; BODY WEIGHT; CYANOBACTERIA; EUTROPHICATION; FEMALE; FERTILITY; LIVER; MALE; MARINE TOXINS; MICE; ORGAN WEIGHT; SUPPORT, NON-U.S. GOV'T;

EID: 0023762338     PISSN: 00984108     EISSN: None     Source Type: Journal    
DOI: 10.1080/15287398809531163     Document Type: Article

References (12)

1. Botes, D. P., Wessels, P. L., Kruger, H., Runnegar, M. T. C., Santicarn, S., Smith, R.J., Barna, J. C. J., and Williams, D. H. 1985. Structural studies on cyanoginosins-LR, -YR, -YA, and -YM, peptide toxins from Microcystis aeruginosa. J. Chem. Soc. Perkin Trans. 1:2747-2748.
2. Burek, J. D., Malella, J. A., and Warren, S. D. 1982. Selected non-neoplastic diseases. In The Mouse in Biomedical Research, vol. 11, eds. H. L. Foster, J.D. Small, and J. G. Fox, p. 427. New York: Academic Press.
3. Carmichael, W. W. 1981. Freshwater blue-green algae (Cyanobacteria) toxins-A review. In The Water Environment-Algal Toxins and Health, ed. W. W. Carmichael, pp. 1-13. New York: Plenum Press.
4. Falconer, I. R., Jackson, A. R. B., Langley, J. V., and Runnegar, M. T. C. 1981. Liver pathology in mice in poisoning by the blue-green alga Microcystis aeruginosa. Aust. J. Biol. Sci. 34:179-187.
5. Falconer, I. R., Beresford, A. M., and Runnegar, M. T. C. 1983. Evidence of liver damage by toxin from a bloom of blue-green alga, Microcystis aeruginosa. Med. J. Aust. 1:511-514.
6. Hawkins, P. R., Runnegar, M. T. C., Jackson, A. R. B., and Falconer, I. R. 1985. Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (WO- LOSZ). SEEMAYA ef SUBBA RAJU isolated from a domestic water supply reservoir, J. Appl. Environ. Microbiol. 50:1292-1295.
7. Jackson, A. R. B., Mclnnes, A., Falconer, I. R., and Runnegar, M. T. C. 1984. Clinical and pathological changes in sheep experimentally poisoned by the blue-green alga Microcystis aeruginosa. Vet. Pathol. 21:102-113.
8. Jackson, A. R. B., Runnegar, M. T. C., Falconer, I. R., and Mclnnes, A. 1985. Cyanobacterial (blue- green algae) toxicity of live-stock. In Plant Toxicology; Proceedings of the Australia-U.S. Sym posium on Poisonous Plants, eds. A. A. Seawright, M. Hegarty, L. F. James, and R. F. Keeler, pp. 499-511. Yeerongpilly: Queensland Department of Primary Industries.
9. Kirpenko, Yu. A., Sirenko, L. A., and Kirpenko, N. I. 1981. Some aspects concerning remote aftereffects of blue-green algae toxin impact on warm-blooded animals. In The Water Environment-Algal Toxins and Health, ed. W. W. Carmichael, pp. 257-269. New York: Plenum Press.
10. Lindsey, J. R., Cassell, G. H., and Davidson, M. K. 1982. Mycoplasmal and other bacterial diseases of the respiratory system. In The Mouse in Biomedical Research, vol. 11, eds. H. L. Foster, J. D. Small, and J. G. Fox, pp. 21-41. New York: Academic Press.
11. Runnegar, M. T. C., and Falconer, I. R. 1982. The in vivo and in vitro biological effects of the peptide hepatotoxin from the blue-green alga Microcystis aeruginosa. S. Afr. J. Sci. 78:363-366.
12. Zilberg, B. 1966. Gastroenteritis in Salisbury European children-A five year study. Cent. Afr. J. Med. 12:164-168.