RANDOMISED CONTROLLED TRIAL OF RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR VERSUS UROKINASE IN THE TREATMENT OF ACUTE PULMONARY EMBOLISM

The Lancet

Volumn 332, Issue 8606, 1988, Pages 293-298

  Goldhaber, SamuelZ ^a   Heit, John ^f   Sharma, G V R K ^c   Nagel, J Stevan ^h   Kim, Ducksoo ^b   Parker, J Anthony ^b   Drum, David ^a   Reagan, Kathleen ^a   Anderson, James ^d   Kessler, CraigM ^e   Markis, John ^b   Dawley, Douglas ^g   Meyerovitz, Michael ^a   Vaughan, DouglasE ^a   Tumeh, SabahS ^a   Loscalzo, Joseph ^a   Selwyn, AndrewP ^a   Braunwald, Eugene ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c Veterans Administration Medical Center at Brockton/West Roxbury ^*  (United Kingdom)

^d HARVARD MEDICAL SCHOOL   (United States)

^e GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^f MAYO CLINIC   (United States)

^g Thoracic Clinic in Portland ^*  (United States)

^h NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; PLASMINOGEN ACTIVATOR;

ADULT; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LUNG EMBOLISM; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ACUTE DISEASE; ADULT; CLINICAL TRIALS; COMPARATIVE STUDY; FEMALE; HUMAN; MALE; MIDDLE AGE; PULMONARY EMBOLISM; RANDOM ALLOCATION; TISSUE PLASMINOGEN ACTIVATOR; URINARY PLASMINOGEN ACTIVATOR;

EID: 0023752733     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(88)92354-9     Document Type: Article

References (16)

1. Acute pulmonary embolism treated with tissue plasminogen activator
2. Perspectives on treatment of acute pulmonary embolism with tissue plasminogen activator
3. Thrombolytic therapy of acute pulmonary embolism Current status and future potential
4. Early reversal of right ventricular dysfunction in patients with acute pulmonary embolism after treatment with intravenous tissue plasminogen activator
5. Pulmonary perfusion after rt-PA therapy for acute embolism: Early improvement assessed with segmental perfusion scanning
6. The Urokinase Pulmonary Embolism Trial. A national cooperative study
7. The sulphite precipitation method for fibrinogen measurement-its use on small samples in the presence of fibrinogen degradation products
8. Quantitative estimation of split products of fibrinogen in human serum, relation to diagnosis and treatment
9. A rapid simple sensitive method for measuring fibrinolytic products in human serum
10. Measurement of cross-linked fibrin derivatives—an immunassay using monoclonal antibodies
11. Recombinant tissue plasminogen activator in acute pulmonary embolism—quantitation of fibrinolytic specificity and hematologic determinants of efficacy
12. Individual comparisons by ranking methods
13. An algorithm for finding the exact significance levels on R x C contingency tables
14. Exact significance testing to establish treatment equivalence with ordered categorical data
15. A randomized, blinded, placebo-controlled trial of recombinant human tissue-type plasminogen activator in patients with unstable angina pectoris