Regional brain glucose utilization in adenylosuccinase-deficient patients measured by positron emission tomography

Pediatric Research

Volumn 24, Issue 2, 1988, Pages 238-242

  De Volder, A G ^a   Jaeken, J ^a,b   Van Den Berghe, G ^a,c   Bol, A ^a   Michel, Ch ^a   Cogneau, M ^a   Goffinet, A M ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c International Institute of Cellular and Molecular Pathology   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

ADENYLOSUCCINATE LYASE DEFICIENCY; BRAIN; CASE REPORT; CHILD; COMPUTER ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; ENZYME DEFICIENCY; GROWTH DISORDER; HUMAN; INBORN ERROR OF METABOLISM; MENTAL DISEASE; METABOLIC DISORDER; MUSCLE ATROPHY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SYMPTOMATOLOGY;

ADENYLOSUCCINATE LYASE; ADOLESCENT; ADULT; BRAIN; CHILD; CHILD, PRESCHOOL; DEOXYGLUCOSE; FLUDEOXYGLUCOSE F 18; GLUCOSE; HUMAN; LYASES; METABOLISM, INBORN ERRORS; SUPPORT, NON-U.S. GOV'T; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0023749672     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1203/00006450-198808000-00020     Document Type: Article

References (15)

1. Jaeken J, Van den Berghe G 1984 An infantile autistic syndrome characterized by the presence of succinyl purines in body fluids. Lancet 2:1058-1061
2. Van den Berghe G, Jaeken J 1986 Adenylosuccinase deficiency. Adv Exp Med Biol 195A:27-33
3. Mazziotta JC, Phelps ME 1986 Positron emission tomography studies of the brain. In: Phelps ME, Mazziotta JC, Schelbert HR (eds) Positron Emission Tomography and Autoradiography: Principles and Applications for the Brain and Heart. Raven Press, New York, pp 493-580
4. Jaeken J, Wadman SK, Duran M, van Sprang FJ, Beemer FA, Holi RA, Theunissen PM, De Cock P, Van den Bergh F, Vincent MF, Van den Berghe G 1988 Adenylosuccinase deficiency: an inborn error or purine nucleotide synthesis. Eur J Pediatr (in press)
5. Hoffman EJ, Phelps ME, Huang SC, Collard PE, Bidaut LM, Schwab RL, Ricci AR 1986 Dynamic, gated and high resolution imaging with the ECAT III. IEEE Trans Nucl Sci 33:452-455
6. Phelps ME, Huang SC, Hoffman EJ, Selin C, Sokoloff L, Kuhl DE 1979 Tomographic measurement of local cerebral glucose metabolic rate in humans with [F-18]2-Fluoro-2-deoxy-D-glucose: validation of method. Ann Neurol 6:371-388
7. Kamo H, McGeer PL, Harrop R, McGeer EG, Calne DB, Martin WRW, Pate BD 1987 Positron emission tomography and histopathology in Pick's disease. Neurology 37:439-445
8. Lowenstein JM 1972 Ammonia production in muscle and other tissues: the purine nucleotide cycle. Physiol Rev 52:382-414
9. Snyder SH 1985 Adenosine as a neuromodulator. Ann Rev Neurosci 8:103-124
10. Stiles GL 1986 Adenosine receptors: structure, function and regulation. Trends Pharmacol Sci 7:486-490
11. Goodman RR, Snyder SH 1982 Autoradiographic localization of adenosine receptors in rat brain using [3H]cyclohexyladenosine. J Neurosci 2:1230-1241
12. Bisserbe JC, Patel J, Marangos PJ 1985 Autoradiographic localization of adenosine uptake sites in rat brain using [3H]nitrobenzylthioinosine. J Neurosci 5:544-550
13. Vincent MF, Van den Berghe G 1988 Influence of succinylpurines on the binding of adenosine to a particulate fraction of rat cerebral cortex. Pediatr Res (in press)
14. Palella TD, Hichwa RD, Ehrenkaufer RL, Rothley JM, McQuillan MA, Young AB, Kelley WN 1985 18F-fluorodeoxyglucose PET scanning in HPRT deficiency. Am J Hum Genet 37:A70
15. Rosenbloom FM, Kelley WN, Miller J, Henderson JF, Seegmiller JE 1967 Inherited disorders of purine metabolism: correlation between central nervous system dysfunction and biochemical defects. JAMA 202:175-181