Effect of cyclosporine on urinary prostanoid excretion, renal blood flow, and glomerulotubular function

Transplantation

Volumn 45, Issue 5, 1988, Pages 883-889

  Petric, Rosemary ^a   Freeman, David ^a   Wallace, Cameron ^a   McDonald, John ^a   Stiller, Calvin ^a   Keown, Paul ^a,b,c  

^a LONDON HEALTH SCIENCES CENTRE   (Canada)

^b ONTARIO MINISTRY OF HEALTH AND LONG TERM CARE   (Canada)

^c VANCOUVER GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; PROSTAGLANDIN; THROMBOXANE;

ANIMAL EXPERIMENT; AUTOIMMUNE DISEASE; DRUG THERAPY; NEPHROTOXICITY; NONHUMAN; ORAL DRUG ADMINISTRATION; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; RAT;

BRAIN; CYCLOSPORINS; GLOMERULAR FILTRATION RATE; KIDNEY; KIDNEY TUBULES; LIVER; NATRIURESIS; PROSTAGLANDINS; REGIONAL BLOOD FLOW; SPLEEN; SUPPORT, NON-U.S. GOV'T; TIME FACTORS;

EID: 0023747422     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-198805000-00008     Document Type: Article

References (57)

1. Canadian Multicentre Transplant Study Group. A randomized clinical trial of cyclosporine in cadaveric renal transplantation. N Engl J Med 1981; 305: 227.
2. Oyer PE, Stinson EB, Jamieson SW, et al. Cyclosporine in cardiac transplantation: a 2V4 year follow-up. Transplant Proc 1983; 15(suppl 1): 2546.
3. Starzl TE, Iwatsuki S, Shaw BW, Gordon RD. Orthotopic liver transplantation. Transplant Proc 1985; 17: 250.
4. Burke CM, Theodore J, Galdwin JC, et al. Twenty-eight cases of human heart/lung transplantation. Lancet 1986; 1: 517.
5. Nghiem DD, Gonwa TA, Corry RJ. Metabolic effects of urinary diversion of exocrine secretions in pancreatic transplantation. Transplantation 1987; 43: 225.
6. Stiller CR, Dupre J, Gent M, et al. Effects of cyclosporine immunosuppression in insulin dependent diabetes mellitus of recent onset. Science 1983; 223: 1362.
7. Schmitz-Schuman M. Interim report of clinical studies presented at the International Symposium on Ciclosporin in Autoimmune Diseases. Prog Allergy 1986; 38: 436.
8. Cyclosporine in autoimmune disease. [Editorial]. Lancet 1985; 1: 809.
9. Bolton CC, Dorol JF, Cuzner ML, Davison AW, Turner AM. Autoimmunity: cyclosporine A therapy in experimental allergic encephalomyelitis. In: White DJ, ed. Proceedings on cyclosporine A. London: Elsevier Biomedical, 1981:135.
10. Dougherty DM, Aronowski J, Orath D, et al. Evidence of neuro- immunologic interactions: cyclosporine modifies opiate with-drawal by effects on the brain and immune components. J NeUroimmunol 1987; 13: 331.
11. Makowka L, Lee G, Cobourn CS, et al. Allogeneic hepatocyte transplantation in the rat spleen under cyclosporine immuno-suppression. Transplantation 1986; 42: 537.
12. Keown PA, Stiller CR, Wallace AC. The nephrotoxicity of cyclosporine. In: Williams GB, Bardick JF, Solez K, eds. Kidney transplant rejection: current issues in diagnosis and treatment. New York: Marcel Dekker, 1986: 431.
13. Bennet WM, Pulliam JP. Cyclosporine nephrotoxicity. Ann Intern Med 1983; 99: 851.
14. Klintmalm G, Sudelin B, Bohman SO, et al. Interstitial fibrosis in renal allografts after 12-46 months of cyclosporine treatment: beneficial effect of low doses in early post transplantation period. Lancet 1984; 1: 950.
15. Sonner BG, Innés JT, Whitehurst RM, et al. Cyclosporine associated renal arteriopathy resulting in loss of allograft function. Am J Surg 1985; 149: 756.
16. Dieperink H, Leyssac PP, Kemp E, Steinbruckl D, Starklint H. Glomerulotubular function in cyclosporine A treated rats. Clin Nephrol 1986; 25(suppl 1): 70.
17. Horstetter TH, Wilkes BM, Brenner BM. Renal circulatory and nephron function in experimental acute renal failure. In: Brenner BM, Lazarus, eds. Acute renal failure. London: Saunders, 1983; 99.
18. Donker AJM, Arise L, Brentiens JR, et al. The effects of indomethacin on kidney function and plasma renin activity in man. Nephron 1976; 12: 288.
19. Nield GH, Rocchi G, Imberti L, Brown Z, Remuzzi G, Williams DG. Effect of cyclosporine on prostacyclin synthesis by vascular tissue in rabbits. Transplant Proc 1983; 15(suppl 1): 2398.
20. Papanicolaou N, Hatziantoniou A, Dontas E-L, et al. Is thromboxane a potent antinatriuretic factor and is it involved in the development of acute renal failure? Nephron 1987; 45: 277.
21. Leaback DH, Walker PG. Studies on glucosaminidase: IV. The fluorimetrie assay of N-acetyl-B-glucosaminidase. Biochem J 1961; 78: 151.
22. Rakusan K, Blahitka J. Cardiac output distribution in rats measured by injection of radiolabelled microspheres via cardiac puncture. Can J Physiol Pharmacol 1974; 52: 230.
23. Ali M, McDonald JWD. Synthesis of thromboxane B2 and 6-keto PGFj by bovine gastric mucosal and muscle microsomes. Pros-taglandins 1980; 20: 245.
24. Donatsch P, Abisch E, Hornberger M, et al. A radioimmunoassay to measure cyclosporin A in plasma and serum samples. J Im-munoassay 1981; 2: 19.
25. Adu D, Turney J, Michael J, McMaster P. Hyperkalemia in cyclosporine treated renal allograft recipients. Lancet 1983; 2: 370.
26. Whiting PH, Thomson AW, Blain JT, et al. Experimental cyclosporin A nephrotoxicity. Br J Exp Pathol 1982; 63: 88.
27. Bergstrand A, Bohmann SO, Farsworth A, et al. Renal histopathology in kidney transplant recipients immunosuppressed with cyclosporin A. Clin Nephrol 1985; 24:107.
28. Duncan JI, Thompson AW, Aldridge RD, Simpson JG, Whiting PH. Cyclosporine-induced renal structural damage: influence of dosage, strain, age, and sex with reference to the rat and guinea- pig. Clin Nephrol 1986; 25(suppl 1): 14.
29. Dieperink H, Kemp E, Leyssac PP, Starklint H. Cyclosporine A: effectiveness and toxicity in a rat model. Clin Nephrol 1986; 25(suppl 1): 46.
30. Dieperink H, Leyssac PP, Starklint H, et al. Nephrotoxicity of cyclosporine A: a lithium clearance and micropuncture study in rats. Eur J Clin Invest 1986; 16: 69.
31. Dieperink H, Starklint H, Leyssal PP. Nephrotoxicity of cyclosporine—an animal model: study of thé nephrotoxic effect of cyclosporine on overall renal and tubular function in conscious rats. Transplant Proc 1983; 15(suppl 1): 2736.
32. Mihatsch MJ, Ryffel B, Hermle M, Brunner FP, Thiel G. Morphology of cyclosporine nephrotoxicity in the rat. Clin Nephrol 1986; 25(suppl 1): 2.
33. Devineni R, McKenzie N, Duplan J, et al. Renal effects of cyclosporine: clinical and experimental observations. Transplant Proc 1983; 15(suppl 1): 2695.
34. Murray BM, Palier MS. Beneficial effects of renal denervation and prazosin on GFR and renal blood flow after cyclosporine in rats. Clin Nephrol 1986; 25(suppl 1): 37.
35. Myers BD, Ross J, Newton L, Leutscher J, Perlroth M. Cyclospor- ine-associated chronic nephropathy. N Engl J Med 1984; 311: 699.
36. Curtis JJ, Luke RG, Dubovsky E, Diethelm AG, Whelchel JW, Jones P. Cyclosporin in therapeutic doses increases renal allo-graft vascular resistance. Lancet 1986; 1: 477.
37. Moss NG, Powell SL, Falk RJ. Intravenous cyclosporine activates afferent and efferent renal nerves and causes sodium retention in innervated kidneys in rats. Proc Natl Acad Sci USA 1985; 82: 8222.
38. Klintmalm G, Ringdon D, Groth CG. Clinical and laboratory signs in nephrotoxicity and rejection in cyclosporine-treated renal allograft recipients. In: Kahan BD, ed. Cyclosporine: biological activity and clinical applications. New York: Grune & Stratton, 1984: 599.
39. Lifschitz MD, Stein JM. Renal vasoactive hormones. In: Brenner BM, Rector FC, eds. The kidney; vol 1. Philadelphia: Saunders, 1981: 650.
40. Duggin GG, Bayter C, Hall BM, Horvath JS, Tiller DJ. Influence of cyclosporine A (CsA) on intrarenal control of GFR. Clin Nephrol 1986; 25(suppl 1): 543.
41. Siegl M, Ryffel B, Petrie R, et al. Cyclosporine, the renin-angio- tensin aldosterone system and renal reactions. Transplant Proc 1983; 15(suppl 1): 2719.
42. Kone BC, Racusen LC, Whelton A, Solez K. Acute renal failure produced by combining cyclosporine and brief renal ischemia in the Munich Wister rat. Clin Nephrol 1986; 25(suppl 1): 5171.
43. Levenson DJ, Simmons CE, Brenner BM. Arachadonic acid metabolism prostaglandins and the kidney. Am J Med 1982; 72: 354.
44. Shnermann J, Briggs JP. Participation of renal cortical prostaglandins in the regulation of glomerular filtration rate. Kidney Int 1981; 19: 802.
45. Wener PC, Siess W. Interaction of renal prostaglandin with the renin-angiotensin system. Pharmacol Ther 1982; 15: 321.
46. Haluska PV, Pollery CT, McDermott J. Thromboxane and prostacyclin in disease: a review. Q J Med 1983; 208: 461.
47. Whisler RL, Lindsey JA, Proctor KV, Morisaki N, Cornwell DG. Characteristics of cyclosporine induction of increased prostaglan-din levels from human peripheral blood monocytes. Transplan-tation 1984; 38: 377.
48. Nield GH, Rocchi G, Imberti L, et al. Effect of cyclosporine A on prostacyclin synthesis by vascular tissue. Thromb Res 1984; 32: 373.
49. Stahl RA, Kudelka S. Chronic cyclosporine A treatment reduces prostaglandin E2 formation in isolated glomeruli and papilla of rat kidneys. Clin Nephrol 1986; 25(suppl 1): 78.
50. Makowka L, Lopatin W, Gilas T, Falk J, Phillips MJ, Falk R. Prevention of cyclosporine (CyA) nephrotoxicity by synthetic prostaglandins. Clin Nephrol 1986; 25(suppl 1): 89.
51. Elzinga L, Kelley VE, Houghton DC, Bennett WM. Modification of experimental nephrotoxicity with fish oil as the vehicle for cyclosporine. Transplantation 1987; 43: 271.
52. Coffman TM, Carr DR, Yarger WE, Klotman PE. Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine toxicity. Transplantation 1987; 43: 282.
53. Lianos E, Andres GA, Dunn MJ. Glomerular prostaglandin and thomboxane synthesis in rat nephrotoxic serum nephritis: effects of hemodialysis. J Clin Invest 1983; 72: 1439.
54. Purkeroon ML, Joist JH, Valdes A, Yates J, Morrison A, Klahr S. Inhibition of thromboxane synthesis ameliorates the progressive kidney disease of rats with subtotal renal ablation. Proc Natl Acad Sci USA 1985; 82: 193.
55. VonWillebrand E, Hayry P. Cyclosporin A deposits in renal allografts. Lancet 1983; 2: 189.
56. Cohen RG, Bieber CP, Hoyt EG, et al. Myocardial fibrosis due to cyclosporine in rat heterotopic heart transplantation. Heart Transplant 1984; 3: 355.
57. Mihatsch MJ, Thiel J, Ryffel R. Morphology of cyclosporine nephropathy. Prog Allergy 1986; 38: 447.