The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

Cell

Volumn 55, Issue 2, 1988, Pages 301-308

  Veillette, André ^a   Bookman, Michael A ^a   Horak, Eva M ^a   Bolen, Joseph B ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE ANTIGEN; PROTEIN TYROSINE KINASE;

ANIMAL CELL; CELL CULTURE; CONTROLLED STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMAL; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CELL LINE; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; PROTEIN-TYROSINE KINASE; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES;

EID: 0023737931     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(88)90053-0     Document Type: Article

References (37)

1. Comodulation of CD3 and CD4
2. Perturbation of the T4 molecules transmits a negative signal in T-cells
3. Adoptive chemoimmunotherapy of murine leukemia with helper T-lymphocyte clones
4. The lymphocyte cytoskeleton and its control of surface receptor functions
5. The src-family of protein kinases
6. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen
7. A thousand and one protein kinases
8. Protein-tyrosine kinases
9. Isolation and oncogenic potential of a novel human src-like gene
10. Distinct epitopes of the T cell antigen receptor of HPB-ALL tumor cells identified by monoclonal antibodies
11. Xenogeneic monoclonal antibodies to mouse lymphoid differentiation antigens
12. Signal transduction through CD4 receptors: stimulatory vs. inhibitory activity is regulated by CD4 proximity to the CD3/T cell receptor
13. Identification of a monoclonal antibody specific for the murine T3 polypeptide
14. The major histocompatibility complex-restricted antigen receptor on T-cells. II. Role of the L3T4 product
15. A lymphocyte-specific protein-tyrosine kinase is rearranged and overexpressed in murine T cell lymphoma LSTRA
16. lck during T-cell activation: functional implications for the src-like tyrosine kinases
17. + cytolytic clones which recognize a tumor-specific cell surface antigen
18. Modulation of sheep erythrocyte receptor expression by anti CD4, anti CD8 and anti HLA antibodies
19. +) subsets among anti-la cytolytic T-cell clones
20. CD4 molecules are associated with the antigen receptor complex on activated but not resting T cells
21. The role of the L3T4 molecule in mitogen and antigen-activated signal transduction
22. Evidence for a physical association of CD4 and the CD3:α:β T-cell receptor
23. A 20-kDa protein associated with the murine T-cell antigen receptor is phosphorylated in response to activation by antigen or concanavalin A
24. Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor
25. IgG or IgM monoclonal antibodies reactive with different determinants of the molecular complex bearing Lyt 2 antigen block T-cell mediated cytolysis in the absence of complement
26. yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family
27. Functional analysis of a cytoplasmic domain-deleted mutant of the CD4 molecule
28. Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens
29. T-cell subsets and the recognition of MHC class
30. Isolation and sequence of L3T4 complementary DNA clones: expression in T cells and brain
31. Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines
32. lck in response to activators of protein kinase C
33. lck) during T-cell activation
34. Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion
35. Role of the L3T4 antigen in T cell activation. II. Inhibition of T cell activation by monoclonal anti-L3T4 antibodies in the absence of accessory cells
36. Evidence implicating L3T4 in class II MHC antigen reactivity: monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen specific proliferation, release of lymphokines, and binding by cloned murine T lymphocyte lines
37. Epidermal growth factor induces rapid, reversible aggregation of the purified epidermal growth factor receptor