Synthetic magainin analogues with improved antimicrobial activity

FEBS Letters

Volumn 236, Issue 2, 1988, Pages 462-466

  Chen, Hao Chia ^a   Brown, Judith H ^a   Morell, John L ^a   Huang, C M ^a,b  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Amphiphilic helix; Antibiotic activity; Peptide design; Structure function relationship

Indexed keywords

MAGAININ 2; MAGAININ DERIVATIVE; SYNTHETIC PEPTIDE;

ANTIMICROBIAL ACTIVITY; CELL CULTURE; CIRCULAR DICHROISM; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMAL; ANTI-INFECTIVE AGENTS; CIRCULAR DICHROISM; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS LAEVIS;

EID: 0023735907     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(88)80077-2     Document Type: Article

References (14)

1. Biological and physical properties of a model calcitonin containing a glutamate residue interrupting the hydrophobic face of the idealized amphiphilic alpha-helical region.