Absolute Configurations and Pharmacological Activities of the Optical Isomers of Fluoxetine, a Selective Serotonin-Uptake Inhibitor

Journal of Medicinal Chemistry

Volumn 31, Issue 7, 1988, Pages 1412-1417

  Robertson, David W ^a   Krushinski, Joseph ^a   Fuller, Ray W ^a   David Leander, J ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; FLUOXETINE; MORPHINE;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAPERITONEAL DRUG ADMINISTRATION; ISOMER; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; RAT; SEROTONIN UPTAKE; STRUCTURE ACTIVITY RELATION; SUBCUTANEOUS DRUG ADMINISTRATION;

ANALGESIA; ANIMAL; BRAIN; CHEMISTRY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPARATIVE STUDY; DRINKING; DRUG SYNERGISM; FLUOXETINE; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; MOLECULAR CONFORMATION; MORPHINE; P-CHLOROAMPHETAMINE; PAIN MEASUREMENT; PROPYLAMINES; RATS; SEROTONIN; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0023734175     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00402a027     Document Type: Article

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