Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice

Nature

Volumn 334, Issue 6184, 1988, Pages 676-682

  Goodnow, Christopher C ^a   Crosbie, Jeffrey ^a   Adelstein, Stephen ^a   Lavoie, Thomas B ^b   Smith Gill, Sandra J ^b   Brink, Robert A ^a   Pritchard Briscoe, Helen ^a   Wotherspoon, John S ^a   Loblay, Robert H ^a   Raphael, Kathy ^c   Trent, Ronald J ^a   Basten, Antony ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b NATIONAL CANCER INSTITUTE   (United States)

^c CSIRO LIVESTOCK INDUSTRIES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN; IMMUNOGLOBULIN D; IMMUNOGLOBULIN M; LYSOZYME;

ANIMAL; B LYMPHOCYTE; GENETIC ENGINEERING; HUMAN CELL; HUMAN EXPERIMENT; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; ANTIBODIES; AUTOANTIGENS; AUTOIMMUNE DISEASES; B-LYMPHOCYTES; FEMALE; GENES, IMMUNOGLOBULIN; HYBRIDOMAS; IMMUNE TOLERANCE; IMMUNOGLOBULIN D; IMMUNOGLOBULIN M; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MURAMIDASE; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES;

EID: 0023729241     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/334676a0     Document Type: Article

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