Maternal serum screening for Down's syndrome in early pregnancy

British Medical Journal

Volumn 297, Issue 6653, 1988, Pages 883-887

  Wald, N J ^a   Cuckle, H S ^a   Densem, J W ^a   Nanchahal, K ^a   Royston, P ^a   Chard, T ^a   Haddow, J E ^a   Knight, G J ^a   Palomaki, G E ^a   Canick, J A ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; CHORIONIC GONADOTROPIN; ESTRIOL;

DOWN SYNDROME; FETUS; HORMONE BLOOD LEVEL; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MATERNAL AGE; METHODOLOGY; PREGNANCY; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; SCREENING;

EID: 0023726523     PISSN: 02670623     EISSN: None     Source Type: Journal    
DOI: 10.1136/bmj.297.6653.883     Document Type: Article

References (8)

1. Wald, N.J.; Cuckle, H.S. Recent advances in screening for neural tube defects and Down syndrome 1987 649 clinical obstetrics and gynaecology. International practice and research. Vol 1. Fetal diagnosis of genetic defects
2. Wald, N.J.; Cuckle, H.S.; Densem, J.W. Maternal serum unconjugated oestriol as an antenatal screening test for Down's syndrome Br J Obstet Gynaecol 1988 10.1111/j.1471-0528.1988.tb06602.x 95 334
3. Bogart, M.H.; Pandian, M.R.; Jones, O.W. Abnormal maternal serum chorionic gonadotrophin levels in pregnancies with fetal chromosome abnormalities Prenat Diagn 1987 10.1002/pd.1970070904 7 623
4. Canick, J.A.; Knight, G.J.; Palomaki, G.E.; Haddow, J.E.; Cuckle, H.S.; Wald, N.J. Low second trimester maternal serum unconjugated oestriol in pregnancies with Down's syndrome BrJ Obstet Gynaecol 1988 10.1111/j.1471-0528.1988.tb06601.x 95 330
5. Benacerraf, B.R.; Gelman, R.; Frigoletto, F.D. Sonographic identification of second-trimester fetuses with Down's syndrome N Engl J Med 1987 10.1056/NEJM198711263172203 317 1371
6. Lockwood, C.; Benacerraf, B.R.; Krinsky, A. A sonographic screening method for Down syndrome AmJ Obstet Gynecol 1987 10.1016/S0002-9378(87)80059-5 157 803
7. Cuckle, H.S.; Wald, N.J.; Thompson, S.G. Estimating a woman's risk of having a pregnancy associated with Down's syndrome using her age and serum alphafetoprotein level BrJ Obstet Gynaecol 1987 10.1111/j.1471-0528.1987.tb03115.x 94 387
8. Royston, J.P. Some techniques for assessing multivariate normality based on the Shapiro-Wilk W Applied Statistics 1983 10.2307/2347291 32 121