Increased Ornithine Decarboxylase Activity in Cultured Cells Exposed to Low Energy Modulated Microwave Fields and Phorbol Ester Tumor Promoters

Cancer Research

Volumn 48, Issue 15, 1988, Pages 4222-4226

  Byus, Craig V ^a   Kartun, K ^a   Pieper, S ^a   Adey, W Ross ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Jerry L Pettis Memorial VA Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ORNITHINE DECARBOXYLASE; PHORBOL ESTER;

ANIMAL CELL; CELL CULTURE; ENZYME ACTIVITY; HEPATOMA CELL; MICROWAVE RADIATION; NONHUMAN;

ANIMAL; CELLS, CULTURED; CRICETULUS; HAMSTERS; LIVER NEOPLASMS, EXPERIMENTAL; MELANOMA; MICROWAVES; ORNITHINE DECARBOXYLASE; PHORBOL ESTERS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; TETRADECANOYLPHORBOL ACETATE;

EID: 0023724351     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Luben, R. A., Cain, C. D., Chen, M. C., Rosen, D. M., and Adey, W. R. Effects of electromagnetic stimuli on bone and bone cells in vitro. Inhibition of responses to parathyroid hormone by low energy fields. Proc. Natl. Acad. Sci. USA, 79:4180-4184,1982.
2. Luben, R. A., and Cain, C. D. Use of bone cell hormone response systems to investigate bioelectromagnetic effects on membranes in vitro. In: W. R. Adey and A. F. Lawrence (eds.), Nonlinear Electrodynamics in Biological Systems, pp. 23–34. New York: Plenum Press, 1984.
3. Byus, C. V, Lundak, R. L., Fletcher, R., and Adey, W. R. Alterations in protein kinase activity following exposure of cultured human lymphocytes to modulated microwave fields. Bioelectromagnetics, 5:341-352,1984.
4. Gilman, P. A., Ames, R. G., and McCawley, M. A. Leukemia risks among U. S. while male coal workers. J. Occup. Med., 27:669-671,1985.
5. Lin, R. S., Dischinger, P. C., Conde, J., and Farrell, K. P. Occupational exposure to electromagnetic fields and the occurrence of brain tumors. J. Occup. Med., 27:413-419,1985.
6. Milham, S. Mortality in workers exposed to electromagnetic fields. Environ. Health Perspect., 62:297-300,1985.
7. Pearson, N. E., Sheppard, R. A., Howard, J. K., Fraser, K., and Lilley, B. M. Leukaemia in electrical workers in New Zealand. Lancet, 1: 811–812, 1985.
8. Spitz, R. M., and Cole-Johnson, C. Neuroblastoma and paternal occupation: a case control analysis. Am. J. Epidemiol., 121:924-929,1985.
9. Swerdlow, A. J. Epidemiology of eye cancer in adults in England and Wales. Am. J. Epidemiol., 118: 292–300, 1983.
10. Tomenius, L. 50-Hz electromagnetic environment and the incidence of childhood tumors in Stockholm county. Bioelectromagnetics, 7: 191–207, 1986.
11. Wertheimer, N., and Leeper, E. Electrical wiring configurations and childhood cancer. Am. J. Epidemiol., 109:273-284,1979.
12. Savtiz, D. A., and Kalle, E. E. Leukemia and occupational exposure to electromagnetic fields: Review of epidemologic survey. J. Occup. Med., 29: 47-51,1987.
13. Wertheimer, N., and Leeper, E. Adult cancer related to electrical wires near the home. Int. J. Epidemiol., 11:345-355,1982.
14. Wertheimer, N., and Leeper, E. Possible effects of electric blankets and heated waterbeds on fetal development. Bioelectromagnetics, 7; 13-22,1986.
15. Wright, W. E., Peters, J. M., and Mack, T. M. Leukaemia in workers exposed to electrical and magnetic fields. Lancet, 2:1160-1161,1982.
16. Thomas, T. L., Stolley, P. D., Stemhagen, A., Fontham, E. T. H., Bleecker, M. L., Stewart, P. A., and Hoover, R. N. Brain tumor mortality risk among men with electrical and electronic jobs: a case-controlled study. J. Natl. Cancer Inst., 79: 233–237, 1987.
17. Pegg, A. E., and Williams-Ashman, H. G. In: D. R. Morris and L. J. Marton (eds.), Polyamines in Biology and Medicine, pp. 3–42. New York: Marcel Decker, 1981.
18. Russell, D. H., Byus, C. V., and Manen, C. A. Proposed model of major sequential biochemical events of a trophic response. Life Sci., 19: 1297-1306,1976.
19. Adey, W. R. Tissue interactions with nonionizing electromagnetic fields. Physiol. Rev., 66:435-514,1981.
20. Adey, W. R. Ionic nonequilibrium phenomena in tissue interactions with electromagnetic fields. In: K. H. Illinger (ed.), American Chemical Society Symposium, No. 157,1981.
21. Adey, W. R., and Lawrence, A. F. (eds.) Nonlinear Electrodynamics in Biological Systems. New York: Plenum Press, 1984.
22. Byus, C. V., and Weiner, R. A. Tumor promoting phorbol ester derivatives increase ornithine decarboxylase activity and polyamine biosynthesis in the liver of the rat and mouse. Carcinogenesis (Lond.), 3:751-755, 1982.
23. O’Brien, T. G., Simsiman, R. C., and Boutwell, R. K. Induction of polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents. Cancer Res., 35:1662-1670,1975.
24. Trevillyan, J. M., and Byus, C. V. Cyclic AMP and tumor promoters cause differential induction of ornithine decarboxylase and accumulation of putrescine in CHO cells deficient in cyclic AMP-dependent protein kinase. Biochim. Biophys. Acta, 762:187-197,1983.
25. Wu, V., Donato, N. M., and Byus, C. V. Growth-state dependent alterations in the ability of 12-O-tetradecanoyl-13-acetate to increase ornithine decarboxylase activity in Reuber H35 hepatoma cells. Cancer Res., 41: 3384-3391,1981.
26. Kikkawa, U., Takai, Y., Tanaka, Y., Miyake, R., and Nishizuka, Y. Calcium-activated, phospholipid-dependent protein kinase from rat brain. J. Biol. Chem., 258: 11442-11445,1983.
27. Niedel, J. E., Kuhn, L. J., and Vandenbark, G. R. Phorbol diester receptor copurifies with protein kinase C. Proc. Natl. Acad. Sci. USA, 80: 36–40, 1983.
28. Balcer-Kubiczek, E. K., and Harrison, G. H. Evidence for microwave carcinogenesis in vitro. Carcinogenesis (Lond.), 6:859-864,1985.
29. Szmigielski, S., Szudzinsld, A., Pietraszek, A., Bielec, M., Janiak, M., and Wrembel, J. K. Accelerated development of spontaneous and benzopyrene-induced skin cancer in mice exposed to 2450 MHz microwave radiation. Bioelectromagnetics, 3:179-191,1982.
30. Byus, C. V., Pieper, S. E., and Adey, W. R. The effects of low-energy 60-Hz environmental fields upon the growth-related enzyme ornithine decarboxylase. Carcinogenesis (Lond.), 8:1385-1389,1987.
31. Wu, V. S., and Byus, C. V. The role of ornithine in the regulation of putrescine accumulation and ornithine decarboxylase activity in Reuber H35 hepatoma cells. Biochim. Biophys. Acta, 804:89-99,1984.
32. Adey, W. R., Bawin, S. M., Barge, R. F., Bassen, H. I., and Franke, K. E. Electric fields in cat brain exposed to 450 MHz semi-far fields, (Abstract). Proceedings of the Bioelectromagnetics Society, 34th Annual Meeting, Washington, DC, p. 35,1981.
33. Adey, W. R., Bawin, S. M., and Lawrence, A. F. Effects of weak amplitude-modulated microwave fields on calcium efflux from awake cat cerebral cortex. Bioelectromagnetics, 3:295-308,1982.
34. Wu, V. S. Involvement of polyamines in the proliferation of rat hepatoma cells stimulated with tumor promoter. PhD Thesis, University of California, Riverside, CA, 1982.
35. Bawin, S. M., and Adey, W. R. Sensitivity of calcium binding in cerebral tissue to weak environmental electric fields oscillating at low frequency. Proc. Natl. Acad. Sci. USA, 73:1999-2003,1976.
36. Bawin, S. M., Kaczmarek, L. K., and Adey, W. R. Effects of modulated VHF fields on the central nervous system. Ann. NY Acad. Sci., 247:74-81,1975.
37. Lin-Liu, S., and Adey, W. R. Low-frequency amplitude-modulated microwave fields change calcium efflux rates from synaptosomes. Bioelectromagnetics, 3:309-322,1982.
38. Lyle, D. B., Schechter, P., Adey, W. R., and Lundak, R. L. Suppression of T lymphocyte cytotoxicity following exposure to sinusoidally amplitude-modulated fields. Bioelectromagnetics, 4:281-292,1983.
39. Dixey, R., and Rein, G. 3H-Noradrenaline release potentiated in a clonal nerve cell line by low-intensity pulsed magnetic fields. Nature (Lond.), 296: 253-256,1982.
40. Jolley, W. B., Hinshaw, D. B., Knierim, K., and Hinshay, D. B. Magnetic field effects on calcium efflux and insulin secretion in isolated rabbit islets of Langerhans. Bioelectromagnetics, 4:103-106,1983.
41. Lichti, U., Yuspa, S. H., and Hennings, H. Ornithine and S-adenosyl methionine decarboxylase in mouse epidermal cell cultures treated with tumor promoters. In: T. J. Slaga, A. Sivak, and R. K. Boutwell (eds.), Carcinogenesis, Vol. 2, pp. 221–232. New York Raven Press, 1978.
42. Lawrence, A. F., and Adey, W. R. Nonlinear wave mechanisms in interactions between excitable tissue and electromagnetic fields. Neurol. Res., 4: 115—153, 1982.
43. Jacobs, S. S., Saltiel, N. E., and Cuatracasas, P. Phorbol ester stimulate the phosphorylation of receptors for insulin and somatomedin C. Proc. Natl. Acad. Sci. USA, 80:6211-6213,1983.
44. Nambi, P., Peters, J. R., Sibley, D. R., and Lefkowitz, R. J. Desensitization of the turkey erythrocyte β-adrenergic receptor in a cell-free system. J. Biol. Chem., 260:2165-2171,1985.
45. Shoyab, M., DeLarco, J., and Todaro, G. Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors. Nature (Lond.), 279:387-391,1979.
46. Zwiller, J., Revel, Marie-Odile, and Malviya, A. N. Protein kinase C catalyzes phosphorylation of guanylate cyclase in vitro. J. Biol. Chem., 260: 1350-1353,1985.
47. Mustelin, T. GTP dependence of the transduction of mitogenic signals through the T3 complex in T lymphocytes indicates the involvement of a G-protein. FEBS Lett., 213:193-203,1987.