Studies on the activity of a protease associated with cells at the advancing edge of human tumour masses in frozen sections

British Journal of Cancer

Volumn 58, Issue 1, 1988, Pages 57-60

  Steven, F S ^a   Griffin, M M ^a   Maier, H ^b,d   Weidauer, H ^b,d   Mangel, W F ^c   Altmannsberger, M ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c Associated Universities Inc   (United States)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

CANCER INVASION; ENZYME INHIBITION; GUANIDINOBENZOATASE; HEAD AND NECK CANCER; HISTOCHEMISTRY; HISTOLOGY; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

AMINOACRIDINES; CARBOXYLIC ESTER HYDROLASES; CARCINOMA, SQUAMOUS CELL; FLUORESCENT DYES; HEAD AND NECK NEOPLASMS; HUMAN; RHODAMINES; SUPPORT, NON-U.S. GOV'T;

EID: 0023720938     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.1988.161     Document Type: Article

References (9)

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2. PIERSCHBACHER, M.D. & RUOSLAHTI, E. (1984). Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature, 309, 30.
3. STEVEN, F.S. & AL-AHMAD, R.K. (1983). Evidence for an enzyme which cleaves the guanidinobenzoate moiety from active site titrants specifically designed to inhibit and quantify trypsin. Eur. J. Biochem., 130, 335.
4. STEVEN, F.S., GRIFFIN, M.M. & AL-AHMAD, R.K. (1985). The design of fluorescent probes which bind to the active centre of guanidinobenzoatase. Applicafion to the location of cells possessing this enzyme. Eur. J. Biochem., 149, 35.
5. STEVEN, F.S., GRIFFIN, M.M. & ALI, H. (1988a). Inhibition of a tumour cell surface protease in vivo and its reactivation by oxidation. Br. J. Cancer, 57, 160.
6. STEVEN, F.S., GRIFFIN, M.M., FREEMONT, A.J. & JOHNSON, J. (1988b). Inhibition of guanidinobenzoatase: evidence for multiple forms of this protease on different tumour cells. J. Enz. Inhibition, 2, 117.
7. STEVEN, F.S., GRIFFIN, M.M., MANGEL, W.F., MAIER, H. & ALTMANNSBERGER, M. (1988c). Inhibition of guanidinobenzoatase by a substrate for trypsin-like enzymes. J. Enz. Inhibitioni (in press).
8. STEVEN, F.S., GRIFFIN, M.M., WONG, T.L.H. & ITZHAKI, S. (1986). Evidence for inhibitors of the cell surface protease guanidinobenzoatase. J. Enz. Inhibition, 1, 127.
9. STEVEN, F.S., JACKSON, H. & BARNETT, F. (1986). Fluorescent location of rat leukaemia cells in resin sections. Int. J. Cancer., 37, 933.