Induction of Immune Tolerance to Factor VIII in Hemophiliacs With Inhibitors

JAMA: The Journal of the American Medical Association

Volumn 259, Issue 1, 1988, Pages 65-68

  Ewing, Nadia P ^a   Sanders, Natalie L ^a   Dietrich, Shelby L ^a   Kasper, Carol K ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8;

ADOLESCENT; ADULT; ARTICLE; CHILD; HEMOPHILIA A; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; MALE; PRESCHOOL CHILD;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; FACTOR VIII; HEMOPHILIA A; HIV SEROPOSITIVITY; HUMAN; MALE;

EID: 0023716966     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.1988.03720010043038     Document Type: Article

References (6)

1. Brackmann HH, Gormsen J: Massive factor-VIII infusion in haemophiliac with factor-VIII inhibitor, high responder. Lancet 1977;2:933.
2. Brackmann HH: Induced immunotolerance in factor VIII inhibitor patients. Prog Clin Biol Res 1986;150:181-195.
3. Aznar JA, Jorquera JI, Peiro A, et al.: The importance of corticoids added to continued treatment with factor VIII concentrates in the suppression of inhibitors in haemophilia A. Thromb Haemost 1984;51:217-221.
4. Kasper CK, Aledort LM, Counts RB, et al.: A more uniform measurement of factor VIII inhibitors. Thromb Haemost 1975;34:875-876.
5. Kasper CK, Ewing NP: Acquired inhibitors of plasma coagulation factors. J Med Technol 1986;3: 431-439.
6. Van Leeuwen EF, Mauser-Bunschoten EP, van Dijken PJ, et al.: Disappearance of factor VIII:C antibodies in patients with haemophilia A upon frequent administration of factor VIII in intermediate or low dose. Br J Haematol 1986;64:291-297.