Incidence and possible clinical significance of k-ras oncogene activation in adenocarcinoma of the human lung

Cancer Research

Volumn 48, Issue 20, 1988, Pages 5738-5741

  Rodenhuis, Sjoerd ^a   Slebos, Robert J C ^a   Evers, Siegina G ^a   Mooi, Wolter J ^a   Boot, Angelina J M ^b   Bos, Johannes L ^b   Wagenaar, Sjoerd Sc ^c   van Bodegom, Peter Ch ^c  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c ST ANTONIUS HOSPITAL   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GENE ACTIVATION; HUMAN; HUMAN CELL; LUNG CARCINOMA; ONCOGENE K RAS; PRIORITY JOURNAL;

ADENOCARCINOMA; CODON; GENE EXPRESSION REGULATION; GENES, RAS; HUMAN; LUNG NEOPLASMS; MUTATION; ONCOGENES; SMOKING; SUPPORT, NON-U.S. GOV'T;

EID: 0023707058     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Barbacid, M. Human oncogenes. In: V. T. DeVita, Jr., S. Hellman, and S. A. Rosenberg (eds.), Important Advances in Oncology 1986, pp. 3-22. Philadelphia: J. B. Lippincott, 1986.
2. Bishop, J. M. The molecular genetics of cancer. Science (Wash. DC), 235: 305-311,1987.
3. Rodenhuis, S. Oncogenes and human lung cancer. In: H. H. Hansen (ed.), Lung Cancer IV. Boston: Martinus Nijhoff Publishing, in press, 1988.
4. Rodenhuis, S., van de Wetering, M., Mooi, W. J., Evers, S. G., van Zandwijk, N., and Bos, J. L. Mutational activation of the K-ras oncogene: A possible pathogenctic factor in adenocarcinoma of the lung. New Engl. J. Med., 317: 929-935, 1987.
5. Barbacid, M. Ras oncogenes. Ann. Rev. Biochem., 56: 779-827, 1987.
6. Barbacid, M. Mutagens, oncogenes and cancer. Trends Genet., 2: 188-192, 1986.
7. Eva, A., and Trimmer, R. W. High frequency of c-K-ros activation in 3-methylcholantrene-induced mouse thymomas. Carcinogenesis (Lond.), 7: 1931-1933,1986.
8. Frazier, M. E., Lindberg, R. A., Mueller, D. M., Gee, A., and Seed, T. M. Oncogene involvement in plutonium induced carcinogenesis. Workshop on Cell Transformation in Radiobiology. Int. J. Radiol. Biol., 49: 524-543, 1986.
9. Stowers, S. J., Glover, P. L., Reynolds, S. H., Boone, L. R., Maronpot, R. R., and Anderson, M. W. Activation of the fi-ras protooncogene in lung tumors from rats and mice chronically exposed to tetranitromethane. Cancer Res., 87:3212-3219, 1987.
10. MeMahem, G., Hanson, L., Lee, J. J., and Wogan, G. N. Identification of an activated c-Ki-ras oncogene in rat liver tumors induced by aflatoxin Bl. Proc. Natl. Acad. Sci. USA, 83:9418-9422, 1986.
11. Guerrero, I., and Pellicer, A. Mutational activation of oncogenes in animal model systems of carcinogenesis. Mutat. Res., 185: 293-308, 1987.
12. Bos, J. L., Verlaan-de Vries, M., Jansen, A. M., Veeneman, G. H., van Boom, J. H., and van der Eb, A. J. Three different mutations in codon 61 of the human N-ras gene detected by synthetic oligonucleotide hybridization. Nucleic Acids Res., 12: 9155-9163, 1984.
13. Saiki, R., Sharf, S., Faloona, F., Mullis, K., Horn, G., Ehrlich, H. A., and Arnheim, N. Enzymatic amplification of β-globin genetic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science (Wash. DC), 230: 1350-1353, 1985.
14. Verlaan-de Vries, M., Bogaard, M. E., van den Elst, H., van Boom, J. H., van der Eb, A. J., and Bos, J. L. A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides. Gene, 50: 313-320, 1986.
15. Sobin, L. H. The World Health Organization's histological classification of lung tumors: A comparison of the first and second editions. Cancer Detect. Prev., 5: 391-406, 1982.
16. Janssen, J. W. G., Steenvoorden, A. C. M., Collard, J. G., and Nusse, R. Oncogene activation in human myeloid leukemia. Cancer Res., 45: 3262-3267, 1985.
17. Bos, J. L., Tokzos, D., Marshall, C. L., Verlaan-de Vries, M., Veeneman, G. H., van der Eb, A. J., van Boom, J. H., Janssen, J. W. G., and Steenvoorden, A. C. M. Ammo-acid substitutions at codon 13 of the N-ros oncogene in human acute myeloid leukemia. Nature (Lond.). 315: 726-730, 1985.
18. Bos, J. L. The ras gene family and human carcinogenesis. Mutat. Res., 795: 255-271, 1988.
19. Bos, J. L., Fearon, E. R., Hamilton, S. R., Verlaan-de Vries, M., van Boom. J. H., van der Eb, A. J., and Vogelstein, B. ras Mutations in human colorectal cancers. Nature (Lond.), 327: 293-297, 1987.
20. Forrester, K., Almoguera, C., Han, K., Grizzle, W. E., and Perucho, M. Detection of high incidence of K-ros oncogenes during human colon tumorigenesis. Nature (Lond.), 327: 298-303, 1987.
21. Vousden, K. H., and Marshall, C. J. Three different activated ras genes in mouse tumours: Evidence for oncogene activation during progression of a mouse lymphoma. EMBO J., 3: 913-917, 1984.