Eicosanoids and inflammation

The Journal of Pathology

Volumn 156, Issue 2, 1988, Pages 101-110

  Williams, K I ^a   Higgs, G A ^b  

^a UNIVERSITY OF BATH   (United Kingdom)

^b WELLCOME RESEARCH LABORATORIES   (United Kingdom)

Author keywords

anti inflammatory drugs; Eicosanoids; inflammation; leukotrienes; prostaglandins; thromboxanes

Indexed keywords

ACETYLSALICYLIC ACID; ICOSANOID; LEUKOTRIENE; PROSTAGLANDIN; THROMBOXANE;

HUMAN; INFLAMMATION; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0023694802     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.1711560204     Document Type: Review

References (113)

1. The release of prostaglandins from the lungs and other tissues
2. Evidence of a membrane bound phospholipase A in rat liver microsomes
3. 2 activity in human platelets by the calcium ionophore A23 187
4. Significance of phospholipase A for prostaglandin formation
5. 2 in plasma membranes and microsomes of rat liver
6. Selective inhibition by mepacrine of the release of “rabbit aorta contracting substance” evoked by administration of bradykinin
7. 2, on arachidonic acid release and prostaglandin synthesis by the guinea pig uterus in vitro
8. Macrocortin: a polypeptide causing the antiphospholipase effect of glucocorticoids
9. 2 inhibitory protein in rabbit neutrophils induced by glucocorticoids
10. Inhibition of prostaglandin synthesis as a possible mechanism of action for the aspirin‐like drugs
11. Acetylation of prostaglandin synthetase by aspirin
12. Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides
13. In‐butyl‐imidazole: a potent and selective inhibitor of thromboxane synthetase
14. Administration to man of UK‐37248‐01, a selective inhibitor of thromboxane synthetase
15. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
16. A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation
17. Leukotrienes: mediators of immediate hypersensitivity reactions of inflammation
18. Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids
19. Leukotriene B: a potential mediator of inflammation
20. 4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence
21. Slow reacting substances of anaphylaxis: Identification of leukotrienes C and D from human and rat sources
22. Inhibition of prostaglandin biosynthesis by eicosa‐5, 8, 11, 14‐tetraynoic acid
23. A new approach to anti‐inflammatory drugs
24. 4‐like activity in vitro
25. The pharmacological properties of a novel series of selective inhibitors of arachidonate 5‐lipoxygenase
26. Liver microsomal cytochrome P450 and the oxidative metabolism of arachidonic acid
27. Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P450 mono‐oxygenase
28. Lipoxins: a novel series of biologically active compounds formed from arachidonic acid in human leukocytes
29. Prostacyclin, thromboxane and leukotrienes
30. Release of histamine, kinin and prostaglandins during carrageenin‐induced inflammation of the rat
31. Reduced exudation and increased tissue proliferation during chronic inflammation in rats deprived of endogenous prostaglandin precursors
32. Release of prostaglandins and incapacitation after injection of endotoxin in the knee joint of the dog
33. Leukocytes and prostaglandins in acute inflammation
34. 2 is the prevailing prostaglandin in the acute inflammatory exudate of urate arthritis in chicken
35. 2 a in epidermis of psoriasis
36. 4
37. Homeostasis of effector systems which can also be recruited for immunological reactions
38. Production of slow reacting substance in rat granulomatous inflammation
39. 4 during experimental inflammation
40. 4 in the yeast inflamed rat paw
41. 2 transformed from arachidonic acid in carrageenin‐induced granuloma
42. A new prostaglandin transformed from arachidonic acid in carrageenin‐induced granuloma
43. Prostaglandin synthesis by rheumatoid synovium and its stimulation by colchicine
44. Prostaglandin production in arthritis
45. Synthesis of arachidonic cyclo‐oxygenase products by rheumatoid and non‐rheumatoid synovial lining in non‐proliferative organ culture
46. 2 biosynthesis by human rheumatoid synovia
47. Prostaglandin biosynthesis by normal and rheumatoid synovial tissue: a comparative study on microsomes and whole homogenates
48. The production of arthritis in rabbits by an immunological reaction to fibrin
49. The role of prostaglandins in rabbit monoarticular arthritis
50. Synthesis of eicosanoids by tissues of the synovial joint during the development of chronic erosive synovitis
51. Effects of anti‐inflammatory drugs on prostaglandins in rheumatoid arthritis
52. Prostaglandin concentrations in synovial fluid in rheumatic diseases: action of indomethacin and aspirin
53. 2 in joint fluid in rheumatoid arthritis
54. Is prostacyclin the major pro‐inflammatory prostanoid in joint fluid?
55. Change of prostaglandin E level in joint fluids after treatment with flurbiprofen in patients with rheumatoid arthritis and osteoarthritis
56. Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthitis
57. 4 in synovial fluid
58. 4, an inflammatory mediator in gout
59. The synovial prostaglandin system in chronic inflammatory arthritis: differential effects of steroidal and non‐steroidal anti‐inflammatory drugs
60. Recovery of prostaglandins in human cutaneous inflammation
61. Prostaglandin activity in human cutaneous inflammation: detection by radioimmunoassay
62. The source of prostaglandins and thromoboxane in experimental inflammation
63. The effects of BW755C and other anti‐inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally‐induced inflammation
64. 1
65. Prostaglandins on cutaneous vasculature
66. Cutaneous vascular reactions to prostaglandins in healthy subjects and in patients with urtricaria and atopic dermatitis
67. The modulation of enhanced vascular permeability by prostaglandins through alterations in blood flow (hyperemia)
68. Role of prostaglandin‐mediated vasodilatation in inflammation
69. 2 and the vascular changes of inflammation
70. Prostaglandins as potentiators of increased vascular permeability in inflammation
71. 2 and arachidonic acid in rabbit skin
72. Control of vascular permeability by polymorphonculear leukocytes in inflammation
73. Prostaglandins, aspirin‐like drugs and the oedema of inflammation
74. 2 as a potentiator of acute inflammation in rats
75. 1 and arachidonic acid to modulate experimentally‐induced oedema in the rat paw
76. 1 a in the rat paw
77. Prostaglandins, aspirin‐like drugs and analgesia
78. The action of chemically pure SRS‐A on the microcirculation in vivo
79. 4 on the microvasculature of guinea pig skin
80. Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response
81. 4: a mediator of vascular permeability
82. Slow reacting substance of anaphylaxis
83. A study of the effect of slow reacting substances of anaphylaxis on the rhesus monkey airway
84. 4
85. Suppression by dexamethasone of vascular permeability response induced with leukotrienes C and D in the rat skin
86. The inflammatory effects of hydroperoxy‐ and hydroxy‐acid products of arachidonate lipoxygenase in rabbit skin
87. 4 and the role of polymorphonuclear leukocytes
88. Structure, function and metabolism of leukotriene constituents of SRS‐A
89. 1 on forearm blood flow
90. Action of prostaglandin in the pregnant woman
91. 2w a on superficial hand veins of man
92. Prostaglandin–oxytocin enhancement and potentiation and their clinical applications
93. 2
94. 4 produces hyperalgesia that is dependent on polymorphonuclear leukocytes
95. Hyperalgesic properties of 15‐lipoxygenase products of arachidonic acid
96. Leukotrienes reduce nociceptive responses to bradykinin
97. 4
98. Prostaglandin‐like activity in the cerebrospinal fluid of febrile patients
99. Prostaglandin E levels in third ventricular cerebrospinal fluid of rabbits during fever and changes in body temperature
100. Anti‐inflammatory drugs, prostaglandins and leukocyte migration
101. The role of cyclic AMP in the chemotactic responsiveness and spontaneous motility of rabbit peritoneal neutrophils
102. Prostaglandins and the microcirculation
103. Inhibition of polymorphonuclear leukocyte adherence by prostacyclin
104. Granulocyte adhesion to enothelium in culture
105. Biogenesis of chemotactic molecules by the arachidonate lipoxygenase system of platelets
106. Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes
107. Chemokinetic activity of arachidonic acid lipoxygenase products on leukocytes from different species
108. The human PMN leukocyte chemotactic activity of complex hydroxy‐eicosatetraenoic acids (HETEs)
109. 4
110. Chemotactic response to some arachidonic acid lipoxygenase products in the rabbit eye
111. Eicosanoids in inflammation