Early function as the principal correlate of graft survival: A multivariate analysis of 200 cadaveric renal transplants treated with a protocol incorporating antilymphocyte globulin and cyclosporine

Transplantation

Volumn 46, Issue 2, 1988, Pages 223-228

  Halloran, Philip F ^a,b,c   Aprile, Marie A ^a,b,c   Farewell, Vern ^a,b,c   Ludwin, David ^a,b,c   Smith, E Kinsey ^a,b,c   Tsai, Shian Y ^a,b,c   Bear, Robert A ^a,b,c   Cole, Edward H ^a,b,c   Fenton, Stanley S ^a,b,c   Cattran, Daniel C ^a,b,c  

^a ST JOSEPH S HOSPITAL   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c UNIVERSITY OF WATERLOO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN; LYMPHOBLAST ANTIBODY; PREDNISONE;

DIAGNOSIS; DRUG THERAPY; GRAFT REJECTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; METHODOLOGY; NEPHROTOXICITY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; STORAGE; SURVIVAL; T LYMPHOCYTE;

ANTILYMPHOCYTE SERUM; CREATININE; CYCLOSPORINS; GRAFT SURVIVAL; HUMAN; KIDNEY; KIDNEY TRANSPLANTATION; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; SUPPORT, NON-U.S. GOV'T; TIME FACTORS;

EID: 0023690456     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-198808000-00007     Document Type: Article

References (42)

1. Green CJ, Allison AC. Extension prolongation of rabbit kidney allograft survival after short term cyclosporine-A treatment. Lancet 1978; 1: 1182.
2. Calne RY, Thiru S, McMaster P, et al. Cyclosporin A in patients receiving renal allografts from cadaver donors. Lancet 1978; 2: 1323.
3. Starzl TE, Klintmalm GBG, Weil R, et al. Cyclosporin A and steroid therapy in sixty-six cadaver kidney recipients Surg Gynecol Obstet 1981; 153; 486.
4. The Canadian Multicenter Transplant Study Group. A randomized clinical trial of cyclosporine in cadaveric renal transplantation. N Engl J Med 1983; 309: 809.
5. The Canadian Multicenter Transplant Study Group. A randomized clinical trial of cyclosporine in cadaveric renal transplantation: analysis at three years. N Engl J Med 1986; 314: 1219.
6. European Multicenter Trial Group. Cyclosporin in cadaveric renal transplantation: one year follow-up of a multicenter trial. Lancet 1983; 2: 986.
7. Kupin WL, Venkat KK, Oh HK, et al. Sequential use of Minnesota antilymphoblast globulin and cyclosporine in cadaveric renal transplantation. Transplantation 1985; 40: 601.
8. Canafax DM, Sutherland DER, Simmons RL, et al. Combination immunosuppression: three drugs (azathioprine, cyclosporine, prednisone) for mismatched related and four drugs (antilymphocyte globulin, azathioprine, cyclosporine, prednisone) for cadaver renal allograft recipients. Transplant Proc 1985; 17: 2671.
9. Simmons RL, Canafax DM, Strand M, et al. Management and prevention of cyclosporine nephrotoxicity after renal transplantation: use of low doses of cyclosporine, azathioprine, and prednisone. Transplant Proc 1985; 17(suppl 1): 266.
10. Kupin W, Venkat KK, Oh HK, et al. Use of cyclosporine and Minnesota antilymphoblast globulin in the early postoperative treatment of primary cadaveric renal transplant recipients. Transplant Proc 1987; 19: 1882.
11. Light JA, Aquino A, Ali A, et al. Quadruple drug therapy prevents graft loss from acute rejection without increasing mortality. Transplant Proc 1987; 19: 1927.
12. Sommer BG, Henry M, Ferguson RM. Sequential antilymphoblast globulin and cyclosporine for renal transplantation. Transplantation 1987; 43: 85.
13. Halloran P, Ludwin D, Bear R, et al. Intermodal immunosuppres sion for cadaver renal transplantation: results using antilymphocyte globulin, azathioprine, cyclosporine, and prednisone. Transplant Proc 1987; 19: 1931.
14. Halloran P, Ludwin D, Aprile M, et al., the Canadian Transplant Study Group. Randomized comparison between cyclosporine and conventional therapy plus Minnesota antilymphocyte globulin in cadaveric renal transplantation. Transplant Proc 1983; 15: 2513.
15. Halloran P, Ludwin D, Aprile M, The Canadian Multicentre Trans plant Study Group. Comparison of antilymphocyte globulin- imuran, cyclosporine, and antilymphocyte globulin-cyclosporine therapy for cadaver renal transplantation. Transplant Proc 1985; 17: 1201.
16. Halloran P, Aprile M, the Ontario Renal Transplant Research Group. A randomized prospective trial of cold storage versus pulsatile perfusion for cadaver kidney preservation. Transplantation 1987; 43: 827.
17. Halloran P, Aprile M, Farewell V, the Ontario Renal Transplant Research Group. Factors influencing early renal function in cadaver kidney transplants: a case-control study. Transplantation 1988; 45: 122.
18. Sanfilippo F, Vaughn WK, Spees EK, et al. The detrimental effects of delayed graft function in cadaver donor renal transplantation. Transplantation 1984; 38: 643.
19. Canafax DM, Torres A, Fryd DS, et al. The effects of delayed function on recipients of cadaver renal allografts: a study of 158 patients randomized to cyclosporine or ALG-azathioprine. Transplantation 1986; 41: 177.
20. Canafax DM, Savik SK, Draxler CT, et al. Cox regression analysis of outcome risk factors in 519 renal allograft recipients. Transplant Proc 1987; 19: 1947.
21. Sanfilippo F, Vaughn WK, Lefor WM, et al. Multivariate analysis of risk factors in cadaver donor kidney transplantation. Transplantation 1986; 42: 28.
22. Tilney NL, Strom TB, Vineyard GC, et al. Factors contributing to the declining mortality rate in renal transplantation. N Engl J Med 1978; 299: 1321.
23. Kaplan EL, Meier P. Non-parametric estimation from incomplete observations. J. Am Statist Assoc 1958; 53: 457.
24. Peto R, Peto J. Asymptotically efficient rank invariant test pro cedures (with discussion). J R Statist Soc A 1972; 135: 185.
25. Cox DR. Regression models and life tables (with discussion). J R Statist Soc B 1972; 1334: 187.
26. Cox DR. The analysis of binary data. London: Methuen, 1970.
27. Whittaker JR, Veith FJ, Soberman R, et al. The fate of the renal transplant with delayed function. Surg Gynecol Obstet 1973; 136: 919.
28. Cho SI, Olsson CA, Bradley JW, Nebseth DC. Regional program for kidney preservation and transplantation in New England. J Surg 1976; 131: 428.
29. Opelz G, Sasaki N, Terasaki PI. Prediction of long-term kidney transplant survival rates by monitoring early graft function and clinical grades. Transplantation 1978; 25: 212.
30. Anderson CB, Sicard GA, Etheredge EE. Delayed primary renal function and cadaver renal allograft results. Surg Gynecol Obstet 1979; 149: 697.
31. Scholz D, Horpacsy G, Mebel M. Late prognosis in acute posttrans plant renal failure in 102 patients. Eur Urol 1979; 5: 14.
32. McDonald JC, Vaughn W, Filo RS, et al. Cadaver donor renal transplantation by centres of the Southeastern Organ Procurement Foundation. Annals of Surgery 1981; 193: 1.
33. Besarab A, Jarrell B, Ihle BU, Colberg JE, Burke JF, Wesson L. Adverse effects of prophylactic irradiation and acute tubular necrosis on renal graft function and survival. Nephron 1982; 31: 347.
34. Heil J, Sutherland ER, Fryd DS, Ascher NL, Simmons RL, Naja rían JS. Acute tubular necrosis of cadaver renal allografts does not correlate with organ sharing or preservation time but portends a poorer prognosis for long-term graft survival. Transplant Proc 1984; 16: 270.
35. Mendez-Picon G, Posner MP, McGeorge MB, et al. The effect of delayed function on long term survival of renal allografts. Surg Gynecol Obstet 1985; 161: 351.
36. Kahan BD, Mickey R, Flechner SM, et al. Multivariate analysis of risk factors impacting on immediate and eventual cadaver allograft survival in cyclosporine-treated recipients. Transplantation 1987; 43: 65.
37. Rocher JI, Landis C, Dafoe DC, Keyserling C, Swartz RD, Camp bell DA Jr. The long-term deleterious effect of delayed graft function in cyclosporine-treated renal allograft recipients. Transplant Proc 1987; 19: 2093.
38. Davison JM, Uldall PR, Taylor RMR. Relation of immediate posttransplant renal function to long-term function in cadaver kidney recipients. Transplantation 1977; 23: 310.
39. Williams GM, White HJO, Hume DM. Factors influencing the long term functional success rate of human renal allografts. Transplantation 1967; 5: 837.
40. Venkateswara Rao K, Andersen RC. Delayed graft function has no detrimental effect on short-term or long-term outcome of cadaveric renal transplantation. Transplant Proc 1985; 17: 2818.
41. Brophy D, Najarían JS, Kjellstrand CM. Acute tubular necrosis after renal transplantation. Transplantation 1980; 29: 245.
42. Barry JM, Norman D, Fuchs EF, Fischer S, Bennett WM. Influence of acute tubular necrosis on first cadaver kidney transplant function. J Urol 1984; 132: 234.