Spherical dosage form with a core and shell. Experiments and modelling

International Journal of Pharmaceutics

Volumn 45, Issue 3, 1988, Pages 217-227

  Liu, H ^a   Magron, P ^a   Bouzon, J ^a   Vergnaud, J M ^a  

^a UNIVERSITÉ JEAN MONNET   (France)

Author keywords

Device with core and shell (empty); Modelling of drug delivery; Polymeric device; Sodium salicylate; Spherical oral dosage device

Indexed keywords

SALICYLATE SODIUM;

DRUG DELIVERY SYSTEM; DRUG RELEASE; MATHEMATICAL MODEL; METHODOLOGY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRELIMINARY COMMUNICATION; PRIORITY JOURNAL;

EID: 0023688027     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(88)90291-8     Document Type: Article

References (29)

1. Modelling of the release of drug in gastric liquid from spheric galenic forms with Eudragit matrix
2. Dissolution of a soluble drug substance from vinyl polymer matrices
3. Model of matter transfers between sodium salicylate-Eudragit matrix and gastric liquid
4. Effect of pH on drug release between sodium salicylate-Eudragit compound and gastric liquid: modelling of the process
5. Dry emulsion, a sustained release form: modelling od drug transfers in liquids
6. Controlled drug delivery based on the use of synthetic polymers
7. Simultaneous nonlinear diffusion of a solvent and organic penetrant in a polymer
8. Modelling of sustained release of water soluble drugs from porous hydrophobic polymers
9. Rate of release of medicaments from ointment based containing drug in suspension
10. Design of oral drug delivery systems: past, present and future
11. Liquid sorption by rubber sheets and evaporation: models and experiments
12. Diffusional release of a solute from a polymeric matrix. Approximate analytical solutions
13. Spheric oral polymer-drug device with two polymers for constant drug delivery
14. Modelling of controlled drug-release in case of carbopol-sodium salicylate matrix in gastric liquid
15. Simultaneous diffusion of benzyl alcohol into plasticized PVC and of plasticizer from polymer into liquid
16. Plasticizer migration from plasticized PVC into liquids. Effect of several parameters on the transfer, I and EC prod
17. Studies of some characteristics of molecular dissolution kinetics from rotating discs
18. Release of bioactive agents from swellable polymers: theory and experiments
19. Analysis of Fickian and non-Fickian drug release from polymers
20. Modelling of drug diffusion through swellable polymeric systems
21. Aspects fondamentaux de la diffusion des principes actifs dans les polymères
22. Study of transfer process of liquid into and plasticizer out of plasticized PVC in using short tests
23. Modelization of matter transfers between PVC and liquid in case of a maximum for liquid-time curves
24. Validation d'un nouveau modèle de libération in vitro
25. Mathematical simulation of controlled drug release from cylindrical matrix devices
26. Drug release from non-disintegrating hydrophilic matrices: sodium salicylate as a model drug