Binding of Amitriptyline to α1‐Acid Glycoprotein and its Variants

Journal of Pharmacy and Pharmacology

Volumn 40, Issue 11, 1988, Pages 767-770

  EAP, C B ^a   CUENDET, C ^a   BAUMANN, P ^a  

^a Hopital de Cery   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; OROSOMUCOID;

DIALYSIS; DRUG PROTEIN BINDING; NONHUMAN;

AMITRIPTYLINE; DIALYSIS; INDICATORS AND REAGENTS; OROSOMUCOID; PROTEIN BINDING; SUPPORT, NON-U.S. GOV'T;

EID: 0023685931     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1988.tb05169.x     Document Type: Article

References (30)

1. Methadone plasma protein binding: Alterations in cancer and displacement from alpha‐1 acid glycoprotein
2. The Contribution of Alpha‐1 Acid Glycoprotein, Lipoproteins, and Albumin to the Plasma Binding of Perazine, Amitriptyline, and Nortriptyline in Healthy Man
3. Selectivity in the binding of psychotropic drugs to the variants of alpha‐1 acid glycoprotein
4. Optical studies on the specific interaction of dipyridamole with Alpha‐1 acid glycoprotein (orosomucoid)
5. Observations on the thermostability of orosomucoid
6. The preparation of orosomucoid from nephrotic urine
7. Protein binding of disopyramide‐displacement by mono‐N‐dealkyldisopyramide and variation with source of Alpha‐1 acid glycoprotein
8. Inheritance of Human Alpha‐1 Acid Glycoprotein (Orosomucoid) Variants
9. The binding of spin‐labelled propranolol and spin‐labelled progesterone by orosomucoid
10. Acute phase proteins as disease markers
11. Steroid‐Protein Interactions. XXXIV. Chemical Modification of Alpha‐1 Acid Glycoprotein for Characterization of the Progesterone Binding Site
12. A practical computer‐based approach to the analysis of radioligand binding experiments
13. Kinetic, Ebda, Ligand, Lowry
14. LIGAND: A Versatile Computerized Approach for Characterization of Ligand‐Binding Systems
15. The Amino Acid Substitutions Found in the Genetic Variants of Alpha‐1 Acid Glycoprotein
16. Alpha‐1 Acid Glycoprotein and Binding of Basic Drugs
17. Plasma protein binding of basic drugs. II. Importance of Alpha‐1 acid glycoprotein for inter‐individual variation
18. Effect of the Sialylation State of Alpha‐1 Acid Glycoprotein on Propranolol Binding
19. 1 acid glycoprotein
20. The Binding of Chemically Different Psychotropic Drugs to Alpha‐1 Acid Glycoprotein
21. Alpha‐1 Acid Glycoprotein
22. Constancy of Alpha‐1 Acid Glycoprotein Variants and Caucasian Patients under Conditions of Severe Stress
23. Structure of Alpha‐1 Acid Glycoprotein. The Complete Amino Acid Sequence, Multiple Amino Acid Substitutions, and Homology with the Immunoglobulins
24. Alterations in Relative Proportions of Microheterogeneous Forms of Human Alpha‐1 Acid Glycoprotein in Liver Disease
25. Free Drug Concentration Monitoring in Clinical Practice. Rationale and Current Status
26. The Binding of Drugs to Blood Plasma Macromolecules: Recent Advances and Therapeutic Significance
27. Interindividual Differences in the Binding of Antidepressants to Plasma Proteins: The Role of the Variants of Alpha‐1 Acid Glycoprotein
28. Binding of Drugs with a Quaternary Ammonium Group to Alpha‐1 Acid Glycoprotein and Asialo Alpha‐1 Acid Glycoprotein
29. The Constancy of the Types of Alpha‐1‐Acid Glycoprotein Variants in Patients with Uterectomy and Irradiation
30. Orosomucoid (ORM) typing by isoelectric focusing: evidence for two structural loci ORM1 and ORM2