Displacement of the bidentate malonate ligand from (d,l-trans-1,2-diaminocyclohexane)malonatoplatinum(II)by physiologically important compounds in vitro

Biochemical Pharmacology

Volumn 37, Issue 17, 1988, Pages 3321-3333

  Mauldin, Stanley K ^a   Plescia, Marcus ^a   Richard, Fred A ^a   Wyrick, Steven D ^b   Voyksner, Robert D ^c   Chaney, Stephen G ^a  

^a WF Goodman Center for Comparative Medical Genetics School of Veterinary Medicine   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c RTI INTERNATIONAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GLUTATHIONE; LIGAND; PLATINUM 1,2 DIAMINOCYCLOHEXANE MALONATE; PLATINUM COMPLEX; RADIOISOTOPE; TISSUE CULTURE MEDIUM;

ANIMAL CELL; CATTLE; COMPLEX FORMATION; DRUG DNA BINDING; DRUG METABOLISM; DRUG SYNTHESIS; LEUKEMIA L 1210; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

AMINO ACIDS; CHEMISTRY; CYCLOHEXANES; KINETICS; LIGANDS; MALONATES; ORGANOPLATINUM COMPOUNDS; SPECTRUM ANALYSIS, MASS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023681741     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(88)90646-6     Document Type: Article

References (31)

1. Platinum drugs: Combined anti-lymphoproliferative and nephrotoxicity assay in rats
2. Interaction of cis-dichlorodiammineplatinum (II) with DNA
3. Tritiated platinum antitumor agents containing the trans-(d,1)-1,2-diaminocyclohexane carrier ligand