Synaptic Protein Tyrosine Kinase: Partial Characterization and Identification of Endogenous Substrates

Journal of Neurochemistry

Volumn 51, Issue 2, 1988, Pages 611-620

  Ellis, Paul D ^a   Bissoon, N ^a   Gurd, James W ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

Polyglutamyltyrosine; Postsynaptic densities; Synaptic membranes; Synaptic protein tyrosine kinase; Val5 Angiotensin II

Indexed keywords

ANGIOTENSIN; PROTEIN TYROSINE KINASE; RADIOISOTOPE;

ANIMAL CELL; ENZYME KINETICS; ENZYME SUBSTRATE; NEUROTRANSMISSION; NONHUMAN; POSTSYNAPTIC DENSITY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SYNAPTIC MEMBRANE;

ANGIOTENSIN II; ANIMAL; KINETICS; MAGNESIUM; MANGANESE; OCTOXYNOL; POLYETHYLENE GLYCOLS; PROTEIN-TYROSINE KINASE; RATS; SOLUBILITY; SUBCELLULAR FRACTIONS; SUPPORT, NON-U.S. GOV'T; SYNAPTIC MEMBRANES;

EID: 0023680002     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.1988.tb01082.x     Document Type: Article

References (55)

1. Decreased phosphorylation of synaptic glycoproteins following hippocampal kindling
2. Membrane phosphoproteins of rat hippocampus: sensitivity to tetanic stimulation and enkephalin
3. Partial purification and characterization of protein tyrosine kinases from normal tissues
4. Isolation and partial characterization of distinct forms of tyrosine protein kinases from rat spleen
5. Identification of the tyrosine protein kinase from LSTRA cells by use of site‐specific antibodies
6. Synaptic plasma membranes from rat brain synaptosomes: isolation and partial characterization
7. Isolation and structural studies on synaptic complexes from rat brain
8. c‐stc
9. The phosphorylation of tyrosyl residues
10. Tyrosine protein kinase activity in normal rat tissue and brain
11. Isolation of synaptic junctional complexes from rat brain
12. Studies of nicotinic acetylcholine receptors in mammalian brain. VI. Isolation of a membrane fraction enriched in receptor function for different neurotransmitters
13. Developmental alterations of rat brain synaptic membranes. Reaction of glycoproteins with plant lectins
14. An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates
15. Identification of a 50000 dalton phosphoprotein with tyrosine kinase activity in a murine lymphoma cell line
16. Two types of receptor for insulin‐like growth factors in mammalian brain
17. Protein tyrosine kinase and protein phosphotyrosine phosphatase in normal and psoriatic skin
18. Phosphorylation of the postsynaptic density glycoprotein gp 180 by endogenous tyrosine kinase
19. In vivo phosphorylation of the postsynaptic density glycoprotein gp 180
20. Isolation and partial characterization of rat brain synaptic plasma membranes
21. Biochemical and morphological comparison of postsynaptic densities prepared from rat, hamster and monkey brains by phase partitioning
22. Association of bovine brain derived growth factor receptor with protein tyrosine kinase
23. Protein‐tyrosine kinase
24. Transforming gene product of Rous sarcoma virus phosphorylates tyrosine
25. Isolation of synaptic plasma membrane from brain by combined sedimentation‐flotation density gradient centrifugation
26. 2+ and calmodulin
27. Cyclic AMP stimulated protein kinases at brain synaptic junctions
28. Experimental approaches to understanding the role of protein phosphorylation in the regulation of neuronal function
29. Substrate specifities of insulin and epidermal growth factor receptor kinases
30. Tyrosine kinase and phosphotyrosine phosphatase activity in human promyelocytic leukemia cells and human polymorphonuclear leukocytes
31. Cleavage of structural proteins during assembly of the head of bacteriophage
32. 4‐di(adenosine‐5') tetraphosphate
33. Tyrosine kinase activity of brain insulin and IGF I receptors
34. src encoded by the proto‐oncogene c‐src is a product of sensory neurons
35. Phosphotyrosine in proteins. Stability and quantification
36. Brain postsynaptic densities: their relationship to glial and neuronal filaments
37. Stimulation of tyrosine phosphorylation of rat brain membrane proteins by calmodulin
38. Protein kinases in the brain
39. Two separate tyrosine protein kinases in human platelets
40. v‐src related tyrosine kinase from bovine brain
41. Association of tyrosine protein kinase activity with mitochondria in human fibroblasts
42. Inhibition of the transformation‐specific kinase in ASV‐transformed cells by N‐α‐tosyl‐L‐lysyl‐chloromethyl ketone
43. Anatomical localization of phosphoprotein and glycoprotein substrates of memory
44. Isolation of rat brain subcellular fraction enriched in putative neurotransmitter receptors and synaptic junctions
45. Evidence of the presence of specific receptors for insulin‐like growth factors I (IGF‐I) and II (IGF‐II) and insulin throughout the adult human brain
46. Insulin‐like growth factor I receptors in neurons and glial cells. Characterization and biological effects in primary culture
47. Fasting and refeeding alter the insulin receptor tyrosine kinase in chicken liver but fail to affect brain insulin receptors
48. c‐src is developmentally regulated in the neural retina
49. Tyrosine protein kinase of spleen and other tissues
50. Regulation of phosphorylation of proteins I, IIIa, and IIIb, in rat neurohypophysis in vitro by electrical stimulation and by neuroactive agents
51. Characterization of the protein apparently responsible for the elevated tyrosine protein kinase activity in LSTRA cells
52. Kindling alters the calcium/calmodulin‐dependent phosphorylation of synaptic membrane proteins in rat hippocampus
53. Tyrosyl protein kinases in normal rat liver: identification and partial characterization
54. Comparison of tyrosine protein kinases in membrane fractions from mouse liver and Ehrlich ascites tumor