The superoxide-forming enzymatic system of phagocytes

Free Radical Biology and Medicine

Volumn 4, Issue 4, 1988, Pages 225-261

  Bellavite, Paolo ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

Chronic granulomatous disease; Cytochrome b558; Flavoprotein; NADPH oxidase; Phagocyte metabolism; Respiratory burst; Superoxide formation; Transduction systems

Indexed keywords

CYTOCHROME B; CYTOCHROME B558; FLAVOPROTEIN; FREE RADICAL; OXIDOREDUCTASE; PROTEIN; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

ENZYMOLOGY; HUMAN; METABOLISM; OXYGEN CONSUMPTION; PHAGOCYTE; REVIEW;

CYTOCHROME B; FLAVOPROTEINS; FREE RADICALS; HUMAN; NADH, NADPH OXIDOREDUCTASES; NADPH OXIDASE; OXYGEN CONSUMPTION; PHAGOCYTES; PROTEINS; QUINONES; SUPEROXIDES; SUPPORT, NON-U.S. GOV'T;

EID: 0023673116     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-5849(88)90044-5     Document Type: Article

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215. 559
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261. Further characterization of NADPH oxidase activity of human polymorphonuclear leukocytes
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263. 2
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271. Vitamin E-a selective inhibitor of the NADPH oxidoreductase enzyme system in human granulocytes
272. Involvement of calmodulin in phagocytotic respiratory burst of leukocytes
273. Studies on the NADPH oxidizing activity in polumorphonuclear leukocytes: The mode of association with the granule membrane, the relationship to myelo peroxidase and the interference of hemoglobin with NADPH oxidase determination
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276. Inhibitory action of chlorpromazine, dibucaine, and other phospholipid-interacting drugs on calcium-activated phospholipid-dependent protein kinase
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281. Calmodulin antagonists modulate rabbit neutrophil degranulation, aggregation and stimulated oxygen consumption
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283. Calmodulation-dependent stimulation of the NADPH oxidase of human neutrophils
284. 2− changes, cAMP and protein kinase C
285. Is cyrosolic ionized calcium regulating neutrophil activation?
286. A transient rise in intracellular free calcium is not a sufficient stimulus for respiratory burst activation in human polymorphonuclear leukocytes
287. 2+ levels
288. 2+ changes in the neutrophil respiratory and secretory response to exogenous phospholipase C and possible involvement of diacylglycerol and protein kinase C.
289. 2+ and primed by subthreshold doses of phorbol myristate acetate
290. Chemotactic factor cuases rapid decreases in phosphatidylinositol, 4,5-biphosphate and phosphatidylinoditol 4-monophosphate in rabbit neutrophils
291. Release and metabolism of arachidonic acid in human neutrophils
292. Identification of distinct activation pathways of the human neutrophil NADPH-oxidase
293. A cytosolic phospholipase in human neutrophils that hydrolyzes arachiodonoyl-containing phosphatidylcholine
294. Rapid formation of diacyglycerol from phosphatidylcholine A pathway for generation of a second messenger
295. Phorbol myristate acetate stimulates diglyceride formation by phosphatidylcholine hydrolysis
296. Activation of phospholipase C in human neutrophils (PMN) by phorbol myristate acetate
297. The appearance of lecithin-32P, synthesized from lysolecithin-23P, in phagosomes of polymorphonuclear leukocytes
298. Remodeling of granulocyte membrane fatty acids during phagocytosis
299. Phospholipid turnover during phagocytosis in human hpolymorphonuclear leukocytes
300. Changes in the incorporation of free fatty acids upon stimulation of human polymorphonuclear leukocytes
301. Use of 1-anilino-8-naphthalene sulfonate to study structural transitions in cell membrane of PMN leucocytes
302. Stimulation of respiration of polymorphonuclear leukocytse by phospholipase C
303. Diacylglycerol, 1-oleoyl-2-acetyl-glycerol, stimulates superoxide generation from human neutrophils
304. Studies on the mechanism of superoxide release from human neutrophils stimulated with arachidonate
305. Effect of saturated and unsaturated fatty acids on the oxidative metabolism of human neutrophils. The role of calcium ion in the extracellular medium
306. Metabolic and morpholical observations on the effect of surface-active agents on leukocytes
307. Mechanism of the respiratory stimulation in saponine-treated leukocytes. The KCN insensitive oxidation of NADPH
308. Activation of NADPH oxidase by arachidonic acid involves phospholipase A2 in intact human neutrophils but not in the cell-free system
309. Phospholipid degradation and signal translation for protein phosphorylation
310. Bacterial lipopolysaccharides, phorbol myristate acetate, and zymosan induce the myristoylation of specific macrophage proteins
311. 2+-dependent protein kinase C
312. Comparative aspects of the production of oxygen radicals by phagocytic cells, and aspects of other effector substances
313. Phorbol 12, myristate 13, acetate (PMA) inhibits the stimulation of phosphoinositide hydrolysis and calcium mobilization and activates the respiratory burst induced by fmet-leu-phe (FMLP) in human neutrophils
314. Phorbol 12-myristate 13-acetate potentiates the respiratory burst while it inhibits phosphinositide hydrolysis and calcium mobilization by Formyl-methionyl-leucyl-phenylalanine in human neutrophils
315. Identification of the predominant substrate for ADP-ribohylation by islet-activating protein
316. ++ mobilization and cellular responses by leukocytes
317. Induction of a transient elevation in intracellular levels of adenosine 3′,5′-cyclic monophosphate by chemotactic factors: An early event in human neutrophil activation
318. 2+
319. 2+-dependent mechanism which is independent of transmembrane activation of adenylate cyclase
320. Cyclic AMP inhibition of phosphoinositide turnover in human neutrophils
321. Phosphorylated proteins as physiolofical effectors
322. Studies and perspectives of protein kinase C
323. Superoxide generation by digitonin-stimulated guinea pig granulocytes. The effects of N-ethylmaleimide, divalent cations, and glycolitic and mitochondrial inhibitors on the activation of the superoxide generating system
324. Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor promoting phorbol esters
325. Phorbol myristane acetate mediates redistribution of protein kinase C in human neutrophls: Potential role in the activation of the respiratory burst enzyme
326. Redistribution of protein kinase C activity of the respiratory burst
327. Co-activation of protein kinase C and NADPH oxidase in the plasma membrane of neutrophil cytoplasts
328. Effect of phorbol 12-myristate 13-acetate and its analogue 4a-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils
329. Protein phosphorylation in intact pig leukocytes
330. Cell alkalinization is not necessary and increased sodium influx is not sufficient for stimulated superoxide production
331. Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst
332. Activation of the human neutrophil nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase by protein kinase. C
333. Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44, 000 protein
334. Surface-reactive stimuli selectively increase protein phosphorylation in human neutrophils
335. 2+-dependent protein kinase C and its substrates in human neutrophils
336. Changes in protein phosphorylation in guinea pig polymorphonuclear-leukocytes by treatment with membrane-perturbing agents with stimulate superoxide anion production
337. Protein kinase C in the phosphorylation of 46 kDa proteins which are phosphorylated in parallel with activation of NADPH oxidase in intact guinea pig polymorphonuclear leukocytes
338. Fc-receptor-mediated protein phosphorylation in murine peritoneal macrophages
339. LPS induces altered phosphate labeling of proteins in murine peritoneal macrophages
340. Phosphorylation of myosin light chain in intact pig luokocytes stimulated by phorbol 12-myristate acetate
341. A possible role for protein phosphorylation in the activation of the respiratory burst in human neutrophils. Evidence for studies with cells from patients with chronic granulonatous disease
342. In vitro phosporylation of a protein related to the NADPH oxidase in human neutrophils
343. Further evidence for the involvement of a phosphoprotein in the respiratory burst oxidase of human neutrophils
344. Respiratory response of phagocytes: terminal NADPH oxidase and the mechanisms of its activation.
345. −245 and associated proteins in human neutrophils
346. 558 after stimulation of the respiratory burst of cytoplasts from polymorphonuclear granulocytes
347. Role of protein kinases in stimulation of human polymorphonuclear leukoctye oxidative metabolism by various agonists
348. Signal transduction in human monocytes: Relationship between superoxide production and the level of kinase C in the membrane
349. Possible involvement of proteases in superoxide production by human polymorphonuclear leukocytes
350. Evidence that proteases are involved in superoxide production by human polymorphonuclear leukocytes and monocytes
351. −-forming enzyme of polymorphonuclear leukocytes with C3b-zymosan
352. Comparative studies on superoxide anion production by polymorophonuclear leukocytes stimulated with various agents
353. A two-fold effect of 1-1-tosylamide-2-phenulethyl chloromethyl ketone on teh oxidative metabolism of guinea pig phagocytes
354. Isolation of protein labeled with diisopropyl fluorophosphate on stimulation of polymorphonuclear leukocytes with immune complexes
355. 2+-requiring proteinase
356. Inhibition of superoxide production by human neutrophils by purified soybean polypeptides. Reevaluation of the involvement of proteases
357. N-a-tosyl-L-lysine chloromethyl ketone and N-a-tosyl-L-phenylalanine chloromethyl ketone inhibit protein kinace C
358. Inhibition of neutrophil sulfhydryl groups by chloromethyl ketones. A mechanism for their inhibition of superoxide production
359. Chemotactic factor-induced generation of superoxide radicals by human neutrophils: Evidence for the role of sodium
360. Transmembrane potential changes associated with superoxide release from human granulocytes
361. Calcium movement and membrane potential changes in the early phase of neutrophil activation by phoorbol myristate acetate: A study with ion selective electrodes
362. Relationship between membrane potential changes and superoxide-releasing capacity in resident and activated mouse peritoneal macrophages
363. Use of lipophilic probes of membrane potential to asses human neutrophil activation. Abormality in chronic granulomatous disease
364. Correlation between membrane potential changes and superoxide production in human granulocytes stimulates stimulated by porthol myristate acetate. Evidence for defective activation in chronic granulomatous disease
365. Studies on stimulus-response coupling in human neutrophils. I. Role of monovalent cations in the respiratory and secretory response to N-Formyl- Methionyl-Leucyl Phenylalanine (FMLP)
366. Independent stimulation of membrane potential changes and the oxidative metabolic burst in polymorphonuclear leukocytes
367. + concentration of the medium
368. Studies on stimulus-response coupling in human neutrophils II Relationships between the effects of changes of external ionic composition on the properties of FMLP receptors and on the respiratory and secretion response
369. Enhancement of neutrophil function as a result of prior exposure to chemotactic factor
370. Chemotactic factor enhancement of superoxide release from fluoride and phorbol myristate acetate stimulated neutrophils
371. Enhanced superoxide anion release from phagocytes by nuramyl dipeptide or lipopolysaccharide
372. Synergism between A23187 and 1-oleoyl-2-acetyl-glycerol in superoxide production by human neutrophils
373. Activation of NADPH oxidase of human neutrophils. Potentiation of chemotactic peptide by a diacylglycerol
374. Gamma interferon is able to enhance the oxidative metabolism of human neutrophils
375. The NADPH oxidase of human polymorphonuclear leukocytes. Evidence for regulation by multiple signals
376. 2+-depleted human neutrophils
377. Activation of human neutrophil NADPH oxidase and lateral mobility of membrane proteins
378. Reversible blockade of the respiratory burst in human neutrophils by a cleavable cross-linking agent
379. The activation of the human neutrophil respiratory burst occurs only at temperatures above 17 °C: Evidence that activation requires membrane fusion
380. Cytochrome b translocation to human neutrophil plasma membranes and super-oxide release. Differential effects on N-formylmethionylleu-cylphenylalanine, Phorbol myristate acetate, and A23187
381. Studies of cytochrome b-245 translocation in the PMA stimulation of the human neutrophil NADPH oxidase
382. Selective enrichment of NADPH oxidase activity in phagosomes from guinea pig polymorphonuclear leukocytes
383. 2 production in human neutrophils stimulated with particles and an effect of cytochalasin-B on the cells
384. 558 translocated into the plasmamembrane from granules during the activation of neutrophils
385. The dissociation of exocytosis and respiratory stimulation in leukocytes by ionophores
386. Expression of a chronic granulomatous disease-like defect by fluoride-exausted neutrophils
387. Activation of a NADPH oxidase from horse polymorphonuclear leukocytes in a cell-free systems
388. Unsaturated fatty acids stimulated NADPH-dependent superoxide production by cell-free system derived from macrophages
389. Activation of NADPH dependent superoxide production in a cell-free system by sodium dodecyl sulfate
390. Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachiodonic acid in a cell-free system
391. Activation of the respiratory burst enzyme from human neutrophils in a cell-free system. Evidence for a soluble cofactor
392. Neutrophil NADPH oxidase: subcellular distribution of arachiodonate-activable enzyme and nature of a cytosolic cofactor
393. Guanine nucleotides stimulate NADPH oxidase in membranes of human neutrophils
394. Subcellular activation of the human NADPH-oxidase by arachidonic acid and sodium dodecyl sulfate (SDS) is independent of protein kinase C
395. Sodium dodecyl sulfate activated superoxide production by macrophage derived cell-free system
396. NADPH oxidase of human neutrophils: Subcellular localization and characterization of an arachidonate-activatable superoxide-generating system
397. NADPH oxidase activator cofactor (ACF): partial purification and absence in a patient with chronic granulomatous disease (CGD)