Regulation of transmembrane signaling by receptor phosphorylation

Cell

Volumn 48, Issue 6, 1987, Pages 913-922

  Sibley, David R ^a   Benovic, Jeffrey L ^a   Caron, Marc G ^a   Lefkowitz, Robert J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR;

ANIMAL; BIOLOGICAL MODEL; CELL MEMBRANE; KINETICS; PHOSPHORYLATION; PHYSIOLOGY; REVIEW;

ANIMAL; CELL MEMBRANE; KINETICS; MODELS, BIOLOGICAL; PHOSPHORYLATION; RECEPTORS, CELL SURFACE;

EID: 0023666159     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(87)90700-8     Document Type: Review

References (104)

1. Phorbol esters induce transient internalization without degradation of unoccupied epidermal growth factor receptors
2. Phosphorylation of the mammalian β-adrenergic receptor by cyclic AMP-dependent protein kinase
3. Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase
4. β-Adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor
5. Self-phosphorylation enhances the protein-tyrosine kinase activity of the epidermal growth factor receptor
6. Regulation of the epidermal growth factor receptor by phosphorylation
7. Purified human platelet-derived growth factor receptor has ligand-stimulated tyrosine kinase activity
8. Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity
9. 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase
10. Reduction of epidermal growth factor receptor affinity by heterologous ligands: evidence for a mechanism involving the breakdown of phosphoinositides and the activation of protein kinase C. Biochem
11. The biochemistry and physiology of the receptor-kinase for epidermal growth factor
12. Suppression of protein tyrosine kinase activity of the epidermal growth factor receptor by epidermal growth factor
13. C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor stimulated tyrosine protein kinase activity
14. Mechanism of insulin action on membrane protein recycling: a selective decrease in the phosphorylation state of insulin-like growth factor II receptors in the cell surface membrane
15. The insulin-like growth factor II receptor is phosphorylated by a tyrosine kinase in adipocyte plasma membranes
16. 1-adrenoceptor binding and phosphatidylinositol metabolism in cultured vascular smooth muscle cells
17. The nature and regulation of the insulin receptor: structure and function
18. Tumor-promoting phorbol diesters mediate phosphorylation of the epidermal growth factor receptor
19. Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal fibroblasts at threonine-654
20. Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654
21. Inhibition of the apparent affinity of the epidermal growth factor receptor caused by phorbol diesters correlates with phosphorylation of threonine-654 but not other sites on the receptor
22. Insulin stimulates cellular iron uptake and causes the redistribution of intracellular transferrin receptors to the plasma membrane
23. Identification of serine 24 as the unique site on the transferrin receptor phosphorylated by protein kinase C
24. Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
25. Autophosphorylation sites on the epidermal growth factor receptor
26. Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences
27. Autophosphorylation and protein kinase C phosphorylation of the epidermal growth factor receptor
28. The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling
29. Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose
30. EGF receptor affinity is regulated by intracellular calcium and protein kinase C
31. Evidence for the platelet-derived growth factor-stimulated tyrosine phosphorylation of the platelet-derived growth factor receptor in vivo
32. Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor
33. cAMP-dependent protein kinase stimulates epidermal growth factor-dependent phosphorylation of epidermal growth factor receptors
34. Specific muscarinic-cholinergic desensitization in the neuroblastoma-glioma hybrid NG108-15
35. Antibodies to the autophosphorylation sites of the epidermal growth factor receptor protein-tyrosine kinase as probes of structure and function
36. Decreased tyrosine kinase activity of insulin receptor isolated from rat adipocytes rendered insulin-resistant by catecholamine treatment in vitro
37. m of the ATP-binding site of the insulin receptor kinase from rat adipocytes
38. Autophosphorylation of the insulin receptor in vitro
39. cAMP-dependent protein kinase phosphorylates the nicotinic acetylcholine receptor
40. Phosphorylation of the nicotinic acetylcholine receptor by an endogenous tyrosine-specific protein kinase
41. Phosphorylation of the nicotinic acetylcholine receptor regulates its rate of desensitization
42. Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells
43. Protein-tyrosine kinases
44. Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane
45. Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells
46. Phosphorylation of receptors for insulin and insulin-like growth factor I
47. The molecular mechanism of insulin action
48. Insulin stimulation of phosphorylation of the β subunit of the insulin receptor
49. Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the β-adrenergic receptor in turkey erythrocytes
50. Effects of protein kinase C activation after epidermal growth factor binding on epidermal growth factor receptor phosphorylation
51. Rapid internalization of the transferrin receptor in K562 cells is triggered by ligand binding or treatment with a phorbol ester
52. Insulin activation of insulin receptor tyrosine kinase in intact rat adipocytes
53. Cloning, sequencing and expression of cDNA for muscarinic acetylcholine receptor
54. Light-regulated binding of rhodopsin kinase and other proteins to cattle photoreceptor membranes
55. Light-dependent phosphorylation of rhodopsin by ATP
56. Phosphorylation of the cardiac muscarinic receptor in intact chick heart and its regulation by a muscarinic agonist
57. Kinetic properties of the insulin receptor tyrosine protein kinase: activation through an insulin-stimulated tyrosine-specific, intramolecular autophosphorylation
58. Mechanism of tumor promoter inhibition of cellular binding of epidermal growth factor
59. 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism
60. 1 MF-2 smooth muscle cells
61. ATP mediates rapid reversal of cyclic GMP phosphodiesterase activation in visual receptor membranes
62. Activation of protein kinase C induces rapid internalization and subsequent degradation of muscarinic acetylcholine receptors in neuroblastoma cells
63. Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells
64. Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms
65. Association of phorbol ester-induced hyperphosphorylation and reversible regulation of transferrin membrane receptors in HL60 cells
66. Mechanism of phorbol diester-induced regulation of surface transferrin receptor involves the action of activated protein kinase C and an intact cytoskeleton
67. Desensitization of the turkey erythrocyte β-adrenergic receptor in a cell-free system
68. Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin
69. Phorbol ester inhibits phosphoinositide hydrolysis and calcium mobilization in cultured astrocytoma cells
70. Rhodopsin and bacteriorhodopsin: structure-function relationships
71. Predominance of tyrosine phosphorylation of insulin receptors during the initial response of intact cells to insulin
72. β-Adrenergic regulation of insulin and epidermal growth factor receptors in rat adipocytes
73. Characterization of platelet-derived growth factor-stimulated phosphorylation in cell membranes
74. Protein tyrosine kinase activity of hormone and growth factor receptors
75. Phosphorylation of the hepatic EGF receptor with cAMP-dependent protein kinase
76. Phosphorylation activates the insulin receptor tyrosine protein kinase
77. The effect of phorbol esters on the receptors for insulin-like peptides (ILAs)
78. Vasopressin inhibition of epidermal growth factor binding to cultured mouse cells
79. Inhibition of epidermal growth factor binding to mouse cultured cells by fibroblast-derived growth factor
80. Characterization of insulin-like growth factor I-stimulated tyrosine kinase activity associated with the β-subunit of type I insulin-like growth factor receptors of rat liver cells
81. Tyrosine protein kinases
82. GTP binding protein: Properties and lack of activation by phosphorylated rhodopsin
83. Biologically active phorbol esters specifically alter affinity of epidermal growth factor membrane receptors
84. Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model
85. Phorbol diesters promote β-adrenergic receptor phosphorylation and adenylate cyclase desensitization in duck erythrocytes
86. Desensitization of turkey erythrocyte adenylate cyclase
87. Homologous desensitization of adenylate cyclase is associated with phosphorylation of the β-adrenergic receptor
88. Phosphorylation/dephosphorylation of the β-adrenergic receptor regulates its functional coupling to adenylate cyclase and subcellular distribution
89. Catecholamine-induced desensitization of turkey erythrocyte adenylate cyclase is associated with phosphorylation of the β-adrenergic receptor
90. Biochemical characterization of phosphorylated β-adrenergic receptors from catecholamine-desensitized turkey erythrocytes
91. Increasing the cAMP content of IM-9 cells alters the phosphorylation state and protein kinase activity of the insulin receptor
92. Phosphorylation of synthetic insulin receptor peptides by the insulin receptor kinase and evidence that the preferred sequence containing Tyr-1150 is phosphorylated in vitro
93. 1-induced translocation of the β-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors
94. 49 lymphoma cells: mechanism of homologous desensitization of adenylate cyclase
95. G-proteins: a family of signal transducers
96. Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells
97. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
98. Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
99. Differences in the sites of phosphorylation of the insulin receptor in vivo and in vitro
100. Light-dependent phosphorylation of rhodopsin: number of phosphorylation sites
101. Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments
102. Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells
103. Tyrosine phosphorylation of insulin receptor β subunit activates the receptor tyrosine kinase in intact H-35 hepatoma cells
104. Similar control mechanisms regulate the insulin and type I insulin-like growth factor receptor kinases