Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA

Cell

Volumn 49, Issue 2, 1987, Pages 229-239

  Parker, Roy ^a   Siliciano, Paul G ^a   Guthrie, Christine ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SMALL NUCLEAR RNA;

ALLELE; ARTICLE; GENE REPRESSION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HYDROGEN BOND; INTRON; NUCLEOTIDE SEQUENCE; RNA SPLICING; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

ALLELES; BASE SEQUENCE; HYDROGEN BONDING; INTRONS; RNA SPLICING; RNA, SMALL NUCLEAR; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, NUCLEIC ACID; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; SUPPRESSION, GENETIC;

EID: 0023663370     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(87)90564-2     Document Type: Article

References (49)

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2. U2 as well as U1 small nuclear ribonucleoproteins are involved in pre-mRNA splicing
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4. The generality of self-splicing RNA: relationship to nuclear mRNA splicing
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7. Use of oligonucleotides for site-specific mutagenesis
8. Lariat structures are in vivo intermediates in yeast pre-mRNA splicing
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14. Transformation of intact yeast cells treated with alkali cations
15. A quantitative analysis of the effects of 5′ junction and TACTAAC box mutants and mutant combinations on yeast mRNA splicing
16. Intron splicing: a conserved internal signal in introns of animal pre-mRNAs
17. Evidence for an introncontained sequence required for the splicing of yeast RNA polymerase II transcripts
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26. Splicing of messenger RNA precursors
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32. Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes
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34. In vivo characterization of yeast mRNA processing intermediates
35. A mechanism for RNA splicing
36. One step gene disruption in yeast
37. Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro
38. Cryptic branch point activation allows accurate in vitro splicing of human β-globin intron mutants
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42. Suppression in the yeast Saccharomyces cerevisiae
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46. Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome
47. A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation