Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

Cell

Volumn 51, Issue 2, 1987, Pages 251-260

  Imagawa, Masayoshi ^a   Chiu, Robert ^a   Karin, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; METALLOTHIONEIN; PROTEIN KINASE C; TRANSCRIPTION FACTOR;

ANIMAL; ARTICLE; BINDING SITE; CELL; CELL FUNCTION; CLASSIFICATION; DRUG EFFECT; ENHANCER REGION; GENETIC TRANSCRIPTION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; PHYSIOLOGY; REGULATOR GENE; VIRUS GENE;

ANIMAL; BINDING SITES; CELL PHYSIOLOGY; CELLS; CYCLIC AMP; ENHANCER ELEMENTS (GENETICS); GENES, REGULATOR; GENES, VIRAL; HUMAN; METALLOTHIONEIN; PROTEIN KINASE C; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0023663116     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(87)90152-8     Document Type: Article

References (56)

1. Activation of non-expressed bovine papilloma virus genomes by tumor promoters
2. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor
3. Cyclic nucleotide phosphodiesterases
4. b class I major histocompatibility gene
5. The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma
6. Enhancement of adenylate cyclase activity in S49 lymphoma cells by phorbol ester
7. A pituitary-specific trans-acting factor can stimulate transcription from the growth hormone promoter in extracts of nonexpressing cells
8. A transcription factor which binds to the enhancer of SV40, immunoglobulin heavy chain and U2 SNRNA genes
9. Organization and expression of eucaryotic split genes coding for proteins
10. Purification and biochemical characterization of the promoter-specific transcription factor, Sp1
11. Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters
12. The coordinated control of metabolic pathways by broad-specificity protein kinases and phosphatases
13. A cyclic AMP- and phorbol ester-inducible DNA element
14. Cell-type specific protein binding to the enhancer of simian virus 40 in nuclear extracts
15. Control of eukaryotic mRNA synthesis by sequence-specific DNA binding proteins
16. Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis
17. α-interferon induced transcription of HLA and metallothionein genes containing homologous upstream sequences
18. A gene can act like an enhancer element
19. Transactivation of an upstream early gene promoter of bovine papilloma virus-1 by a product of the viral E2 gene
20. The SV40 enhancer is composed of multiple functional elements that can compensate for one another
21. Phorbol ester induces the transcriptional stimulatory activity of the SV40 enhancer
22. Metallothionein gene expression is regulated by serum factors and activators of protein kinase C
23. Interferon response sequence potentiates activity of an enhancer in the promoter region of a mouse H-2 gene
24. 2-microglobulin genes
25. Affinity purification of sequence-specific DNA-binding proteins
26. Metallothioneins: proteins in search of function
27. Activation of a heterologous promoter in response to dexamethasone and cadmium by metallóthionein gene 5′-flanking DNA
28. A gene
29. A enhancer activity
30. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor
31. b promoter: enhancer-like sequences and their role in regulation of class I gene expression
32. Induction of a factor that binds to the polyoma virus A enhancer on differentiation of embryonal carcinoma cells
33. A gene in vitro also interact with the SV40 promoter and enhancer region
34. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
35. Tissue-specific expression of the human growth hormone gene is conferred in part by the binding of a specific trans-acting factor
36. Protein-binding sites in the lg gene enhancer determine transcriptional activity and inducibility
37. Biochemistry of interferons and their actions
38. Regulation of inducible and tissue-specific gene expression
39. Transcriptional selectivity of viral genes in mammalian cells
40. Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene identification of an upstream control region
41. Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen
42. Binding of a nuclear protein to the cyclic AMP response element of the somatostatin gene
43. Identification of a cyclic AMP responsive element within the rat somatostatin gene
44. Studies and perspectives of protein kinase C
45. Discrete elements within the SV40 enhancer region display different cell-specific activities
46. Early signals in the mitogenic response
47. The SV40 enhancer can be dissected into multiple segments, each with a different cell type specificity
48. In vivo competition between a metallothionein regulatory element and the SV40 enhancer
49. Forskolin: its biological and chemical properties
50. Inducibility of the κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism
51. Enhancers and eukaryotic gene transcription
52. Cyclic AMP regulation of the human glycoprotein hormone α-subunit gene is mediated by an 18-base-pair element
53. Transcriptional inactivation of c-myc and the transferrin receptor in dibutyrl cyclic AMP-treated HL-60 cells
54. Multiple point mutations affecting the simian virus 40 enhancer
55. Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans-acting factor
56. Multiple sequence motifs are involved in SV40 enhancer function