Dieldrin inhibition of gap junctional intercellular communication in rat glial cells as measured by the fluorescence photobleaching and scrape loading/dye transfer assays

Toxicological Sciences

Volumn 9, Issue 4, 1987, Pages 785-794

  Suter, S ^a   Trosko, J E ^a   El fouly, M H ^a   Lockwood, L R ^a   Koestner, A ^b  

^a Dept of Pharmacology and Toxicology   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIELDRIN;

ANIMAL CELL; BIOASSAY; CELL COMMUNICATION; CELL JUNCTION; CENTRAL NERVOUS SYSTEM; FLUORESCENCE; GLIA CELL; METHODOLOGY; NERVOUS SYSTEM; NONHUMAN; RAT;

ANIMAL; CELL COMMUNICATION; COLONY-FORMING UNITS ASSAY; DIELDRIN; FLUORESCENCE; NEUROGLIA; RATS; SPECTROMETRY, FLUORESCENCE; STAINING AND LABELING; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0023637524     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/9.4.785     Document Type: Article

References (52)

1. ANDREW, R. D, MACVICAR, B. A., DUDEK, F. E., AND HATTON, G. I. (1981). Dye transfer through gap junctions between neuroendocrine cells of rat hypothalamus. Science 211, 1187-1189.
2. ASHWOOD-SMITH, M. J. (1981). The genetic toxicology of aldrin and dieldnn. Mulal Res 86, 137-154.
3. ATKINSON, M. M, ANDERSON, S. K., AND SHERIDAN, J. D. (1986). Modification of gap junctions in cells transformed by a temperature-sensitive mutant of Rous sarcoma virus. J Membr. Biol., 91, 53-64.
4. ATKINSON, M., AND SHERIDAN, J. (1984). Decreased junctional permeability in cells transformed by three different viral oncogenes: A quantitative video analysis. J Cell Biol., 99, 401a.
5. AZARNIA, R., AND LOEWENSTEIN, W. R. (1984). Intercellular communication and the control of growth: X. Alterations of junctional permeability by the src gene. A study with temperature-sensitive mutant Rous sarcoma virus. J. Membr. Biol., 82, 191-212.
6. AZARNIA, R., AND LOEWENSTEIN, W. R. (1987). Polyomavirus middle T antigen downregulates junctional cell to cell communication. Mol. Cell Biol., 7, 946-950.
7. BENNETT, M. V. L., AND GOODENOUGH, D. A. (1978). Gap junctions, electronic coupling and intercellular communication. Neurosci. Res. Program Bull., 16, 373-486.
8. BENNETT, M. V. L., SPRAY, D. C., AND HARRIS, A. L. (1981). Electrical coupling in development. Amer Zool., 21, 413-427.
9. BENNETT, M. V. L., ZIMERING, M. B., SPIRA, M. E., AND SPRAY, D. C. (1985). Interaction of electrical and chemical synapses. In Gap Junctions (M. V. L. Bennett and D. C. Spray, Eds.), pp. 355-366. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
10. CHANG, C C., TROSKO, J. E., RUNG, H.-J., BOMICK, D., AND MATSUMURA, F. (1985). Potential role of the src gene product in the inhibition of gap junctional communication in NIH/3T3 cells. Proc. Natl. Acad. Sci USA 82, 5360-5364.
11. DAVIDSON, J. S., BAUMGARTEN, I. M., AND HARLEY, E. H. (1985). Effects of 12-D-tetradecanoylphorbol-13-acetate and retinoids on intercellular junctional communication measured with a citrulline incorporation assay. Carcinogenesis 6, 645-650.
12. EL-FOULY, M. H. TROSKO, J. E., AND CHANG, C. C. (1987). Scrape-loading and dye transfer: A rapid and simple technique to study gap junctional intercellular communication. Exp Cell Res 168, 422-430.
13. FINBOW, M. E., AND YANCEY, S. B. (1981). The roles of intercellular junctions. In Biochemistry of Cellular Regulation (M. J. Clemens. Ed.), Vol. 4, pp. 215-249. CRC Press, Boca Raton, FL.
14. FINDLAY, I., AND PETERSEN, O. H. (1982). Acetylcholine evoked uncoupling restricts the passage of lucifer yellow between pancreatic acinar cells. Cell Tissue Res., 225, 633-638.
15. FURSHPAN, E. J., AND POTTER, D. D. (1959). Transmission of the giant motor synapses of crayfish. J Physiol 145, 289-325.
16. GUPTA, R. S., SINGH, B., AND STETSKO, D. K. (1985). Inhibition of metabolic cooperation by phorbol esters in a cell culture system based on adenosine kinase deficient mutants of V79 cells. Carcinogenesis 6, 1359-1366.
17. HERTZBERG, E. L., LAWRENCE, T. S., AND GILULA, N. B. (1981). Gap junctional communication. Annu. Rev. Physiol., 43, 479-491.
18. HOOPER, M. L. (1982). Metabolic cooperation between mammalian cells in culture. Biochim. Biophys. Acta 651, 85-103.
19. ICPEMC Tast Group 5. (1984). Report of ICPEMC Task Group 5 on the differentiation between genotoxic and non-genotoxic carcinogens. Mutat. Res., 133, 1-49.
20. ITO, N., TATEMATSU, M., NAKANISHI, K., HASEGAWA, R., TAKANO, T., IMAIDA, K., AND OGISO, T. (1980). The effects of various chemicals on the development of hyperplastic liver nodules in hepatectomized rats treated with iV-nitrosodiethylamine or N-2-fluorenyl-acetamide. Gann 71, 832-842.
21. IWATSUKI, N., AND PETERSON, O. H. (1978). Electrical coupling and uncoupling of exocrine acinar cells. J Cell Biol., 79, 533-545.
22. JONE, C, TROSKO, J. E., AYLSWORTH, C. F., PARKER, L., AND CHANG, C. C. (1985). Further characterization of the in vitro assay for inhibitors of metabolic cooperation in the Chinese hamster V79 cell line. Carcinogenesis 6, 361-366.
23. JOY, R. M. (1982). Mode of action of lindane, dieldrin, and related insecticides in the central nervous system. Neurobehav. Toxicol. Teralol., 4, 813-823.
24. Ko, L., KOESTNER, A., AND WEICHSLER, W. (1980). Morphological characterization of nitrosource-in-duced glioma cell lines and clones. Acta Neuropathol 51, 23-31.
25. LARSEN, W. J. (1983). Biological implications of gap junction structure, distribution and composition. A review. Tissue Cell 15, 645-671.
26. LARSEN, W. J., AND RISINGER, M. A. (1985). The dynamic life histories of intercellular membrane junctions. Mod. Cell Biol., 4, 151-216.
27. LASATER, E. M., AND DOWLING, J. E. (1985). Dopamine decreases conductance of the electrical junctions between cultured retinal horizontal cells. Proc Nati Acad. Sci. USA 82, 3025-3029.
28. LIN, Z.-X., KAVANAGH, T., TROSKO, J. E., AND CHANG, C. C. (1986). Inhibition of gap junctional intercellular communication in human teratocarcinoma cells by organochlorine pesticides. Toxicol. Appl. Pharmacol., 83, 10-19.
29. LOEWENSTEIN, W. R. (1966). Permeability of membrane junctions. Ann. N. Y. Acad. Sci., 137, 441-472.
30. LOEWENSTEIN, W. R. (1979). Junctional intercellular communication and the control of growth. Biochim. Biophys. Acta 560, 1-65.
31. LOEWENSTEIN, W. R., AND KANNO, Y. (1966). Intercellular communication and the control of tissue growth. Lack of communication between cancer cells. Nature (London) 209, 1248-1249.
32. MALCOLM, A. R., MILLS, L. J., AND MCKENNA, E. J. (1985). Effects of phorbol myristate acetate, phorbol dibutyrate, ethanol, dimethylsulfoxide, phenol and seven metabolites of phenol on metabolic cooperation between Chinese hamster V79 lung fibroblasts. Cell Biol. Toxicol., 1, 265-283.
33. MASSA, P. T., AND MUGNAINI, E. (1985). Cell-cell junctional interactions and characteristic plasma membrane features of cultured rat glial cells. Neuroscience 14, 695-709.
34. MCCANN, J., CHOI, E., YAMASAKI, E., AND JAMES, B. N. (1975). Detection of carcinogen as mutagens in the salmonella/microsome test: Assay of 300 chemicals. Proc. Natl Acad. Sci. USA 72, 5135-5139.
35. MURRAY, A. W., AND FITZGERALD, D. J. (1979). Tumor promoters inhibit metabolic cooperation in cocultures of epidermal and 3T3 cells. Biochem. Biophys. Res. Commun., 91, 395-401.
36. NEYTON, J., AND TRAUTMANN, A. (1986). Acetylcholine modulation of the conductance of intercellular junctions between rat lacrimal cells. J. Physiol 377, 283-295.
37. ORKAND, R. K. (1977). Glial cells. In Handbook of Physiology, Vol. 1, Section 1, Cellular Biology of Neurons (J. M. Brookhart, V. B. Mountcastle, E. R. Kandel, and S. R. Geiger, Eds.), pp. 855-875. Waverly Press, Baltimore.
38. PICCOLINO, M., NEYTON, J., AND GERSCHENFELD, H. M. (1984). Decrease of gap junctional permeability induced by dopamine and cyclic adenosine 3'-5'-monophosphate. J Neurosci., 4, 2477-2488.
39. PITTS, J. D. (1980). The role of junctional communication in animal tissues. In Vitro 16, 1049-1056.
40. PROBST, G. S., MCMAHAN, R. E., HILL, L. E., THOMPSON, C. Z., Epp, J. K., AND NEAL, S. B. (1981). Chemically induced unscheduled DNA synthesis in primary rat hepatocytes: A comparison with bacterial mutagenicity using 218 compounds. Environ Mutat., 3, 11-32.
41. PURCHASE, I. F. H., LONGSTAFF, E., ASHBY, J., STYLES, J. A., ANDERSON, D., LEFEVREM, P. A., AND WESTWOOD, R. F. (1978). An evaluation of 6 short-term tests for detecting organic chemical carcinogens. Bril J. Cancer 37, 873-902.
42. SCHULTZ, R. M. (1985). Roles of cell to cell communication in development. Biol Reprod., 32, 27-42.
43. SUBAK-SHARPE, J. H., BURK, R. R., AND PITTS, J. D. (1969). Metabolic cooperation between biochemically marked mammalian cells in culture. J. Cell. Sci., 4, 353-367.
44. TENNEKES, H. A., EDLER, L., AND KUNZ, H. W. (1982). Dose response analysis of the enhancement of liver tumor formation in CF-1 mice by dieldrin. Carcinogenesis 3, 911-919.
45. TERANISHI, T., NEGISHI, K., AND KATO, S. (1983). Dopamine modulates 5-potential amplitude and dye coupling between external horizontal cells in carp retina. Nature (London) 301, 243-246.
46. TONG, C, FAZIO, M., AND WILLIAMS, G. M. (1981). Rat hepatocyte-mediated mutagenesis of human cells by carcinogenic polycyclic aromatic hydrocarbons but not organochlorine pesticides. Proc. Soc Exp Biol Med., 167, 572-575.
47. TROSKO, J. E., AND CHANG, C. C. (1984). Adaptive and nonadaptive consequences of chemical inhibition of intercellular communication. Pharmacol Rev 36, 137s-144s.
48. TROSKO, J. E., CHANG, C. G, AND MEDCALF, A. (1983). Mechanisms of tumor promotion: Potential role of intercellular communication. Cancer Invest 61, 511-526.
49. TROSKO, J. E., JONE, C, AND CHANG, C. C. (1987). In vitro detection of chemicals which inhibit gap junctional-mediated intercellular communications: Al drin, dieldrin and toxaphene as examples. Biochem Toxicol., 1, 83-93.
50. TROSKO, J. E., YOTTi, L. P., WARREN, S. T., TSUSHIMOTO, G., AND CHANG, C. C. (1982). Inhibition of cell-cell communication by tumor promoters. In Carcinogenesis (E. Hecker, N. E. Fusemg, W. Kunz, F. Marks, and H. W. Thielman, Eds.), Vol. 7, pp. 565-585. Raven Press, New York.
51. WADE, M., TROSKO, J. E., AND SCHINDLER, M. (1986). A fluorescence photobleaching assay of gap junction mediated cell-cell communication between human cells. Science 232, 429-552.
52. YOTTI, L. P., CHANG, C. C, AND TROSKO, J. E. (1979). Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter. Science 206, 1089-1091.