Mismatches between neurotransmitter and receptor localizations in brain: observations and implications

Neuroscience

Volumn 23, Issue 1, 1987, Pages 1-38

  Herkenham, M ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

5 HT1; 5 HT2; acetycholine; acetylcholinesterase; ACh; AChE; ANP; atrial natriuretic peptide; BH; Bolton Hunter; calcitonin gene related peptide; CCK; cerebrospinal fluid; CGRP; ChAT; cholecystokinin; choline acetyltransferase; corticotropin releasing factor; CRF; CSF; neuropeptide Y; NPY; serotonin; SP; spiperone; substance P; thyrotropinreleasing hormone; TRH; vasoactive intestinal peptide; VIP

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; GLUTAMIC ACID; MONOAMINE; NEUROPEPTIDE; NEUROTRANSMITTER;

ANIMAL CELL; CENTRAL NERVOUS SYSTEM; CYTOLOGY; ELECTRON MICROSCOPY; NERVOUS SYSTEM; NONHUMAN; REVIEW; SYNAPSE; ULTRASTRUCTURE;

ANIMAL; BRAIN; INTERCELLULAR JUNCTIONS; NEUROTRANSMITTERS; RECEPTORS, NEUROTRANSMITTER; SYNAPTIC TRANSMISSION;

EID: 0023634852     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/0306-4522(87)90268-5     Document Type: Article

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211. An immunohistochemical study of endopeptidase-24.11 (“enkephalinase”) in the pig nervous system
212. Nonsynaptic peptidergic neurotransmission in the abdominal ganglion of Aplysia
213. Nonsynaptic characteristics of neurotransmission mediated by egg-laying hormone in the abdominal ganglion of Aplysia
214. The distribution and morphology of opioid peptide immunoreactive neurons in the cerebral cortex of rats
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238. 3H-l-glutamate binding sites
239. 3H]AMPA binding sites in rat brain as determined by quantitative autoradiography
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241. Light and electron microscopic studies of calcitonin gene-related peptide-like immunoreactive neurons and axon terminals of the nucleus of the tractus solitarius of the rat
242. Depolarizing action of GABA (γ-aminobutyric acid) on myelinated fibers of peripheral nerves
243. The distribution and orientation of noradrenergic fibers in neocortex of the rat: an immunofluorescence study
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247. Evidence for substance P in the habenulo-interpeduncular tract
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258. Quantitative autoradiography of muscarinic cholinergic receptors in the rat brain
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260. A new major projection from locus coeruleus: the main source of noradrenergic nerve terminals in the ventral and dorsal columns of the spinal cord
261. Pharmacological properties of the postsynaptic inhibition by Purkinje cell axons and the action of γ-aminobutyric acid on Deiters' neurones
262. Active clearance of corticotropin-releasing factor from the cerebrospinal fluid
263. 3H]Bicuculline methochloride binding to low-affinity γ-aminobutyric acid receptor sites
264. 3H]bicuculline methochloride
265. Biochemical pharmacology of the γ-aminobutyric acid receptor/ionophore protein
266. Distribution of γ-aminobutyric acid-immunoreactive neurons in the septal region of the rat brain
267. GABA-containing neurons in the thalamus and pretectum of the rodent
268. Beta-adrenergic receptor localization by light microscopic autoradiography
269. Neurotensin receptors are located on dopamine-containing neurones in rat midbrain
270. 3H]Spiperone binding sites in brain: autoradiographic localization of multiple receptors
271. Axonal transport of neurotransmitter receptors studied by quantitative autoradiography
272. High affinity GABA receptors—autoradiographic localization
273. 3H]muscimol binding in substantia nigra entopeduncular nucleus, globus pallidus, and thalamus after striatal lesions as demonstrated by quantitative receptor autoradiography
274. Quantitative autoradiographic mapping of serotonin receptors in rat brain. II. Serotonin-2 receptors
275. Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors
276. Electron immunocytochemistry in vasoactive intestinal peptide (VIP) in the rat brain
277. Quantitative autoradiography of GABA and benzodiazepine binding in studies of mammalian and human basai ganglia function
278. 3H]muscimol binding in rat brain
279. 1 receptor sites and functional correlates
280. 1 receptors to human and canine basilar arteries
281. Neurotransmitter receptor binding in bovine cerebral microvessels
282. Neuropeptides and their receptors: a psychosomatic network.
283. Immunocytochemical localization of choline acetyltransferase in rat ventral striatum: a light and electron microscopic study
284. Immunocytochemical localization of enkephalin in the neostriatum of rat brain: a light and electron microscopic study
285. Enkephalin receptors on dopaminergic neurons in rat striatum
286. Cerebrospinal fluid as neuroregulatory pathway. Peptides in neuropsychiatric illness
287. Metabolism of thyrotropin-releasing hormone in human cerebrospinal fluid. Isolation and characterization of pyroglutamate aminopeptidase activity
288. Characterization and distribution of receptors for the atrial natriuretic peptides in mammalian brain
289. Multiple tachykinin receptors in guinea pig brain. High densities of substance K (neurokinin A) binding sites in the substantia nigra
290. 3H]neurotensin receptors in rat brain: Visualization by tritium-sensitive film
291. Autoradiographic distribution of substance P receptors in rat central nervous system
292. Hypothesis: a central neuroendocrine system regulates brain ion homeostasis and volume
293. 3H]prazosin binding sites in rat forebrain
294. 2-adrenergic receptors in rat brain
295. Evidence for a ‘paravascular’ fluid circulation in the mammalian central nervous system, provided by the rapid distribution of tracer protein throughout the brain from the subarachnoid space
296. Autoradiographic mapping of somatostatin receptors in the rat central nervous system and pituitary
297. Immunocytochemical localization of glutamic acid decarboxylase in neuronal somata following colchicine inhibition of axonal transport
298. Distribution of neuropeptides in the limbic system of the rat: the hippocampus
299. Opiate receptors
300. Distributions of choline acetyltransferase and acetylcholinesterase activities in layers of rat superior colliculus
301. The postnatal development of VIP binding sites in rat forebrain and hindbrain
302. 5-enkephalin binding to rat brain membranes: evidence that oxymorphone is a non-competitive inhibitor of the lower affinity δ-binding site
303. Preparation of rat brain membranes highly enriched with opiate kappa binding sites using site-directed acylating agents: optimization of assay conditions
304. Autoradiographic localization of a novel peptide binding site in rat brain using the substance P analog, eledoisin
305. Visualization of rat brain receptors for the neuropeptide, substance P
306. 3H]propylbenzilylcholine mustard and its distribution in the forebrain
307. 3H]propylbenzilylcholine mustard in the midbrain and hindbrain
308. Neuropeptides modulate the β adrenergic response of purified astrocytes in vitro
309. Implications of neuropeptides in neurological diseases
310. Distribution and efferent projections of corticotropin-releasing factor-like immunoreactivity in the rat amygdaloid complex
311. Immunohistochemical localization of enkephalin in rat brain and spinal cord
312. 3H]SCH23390
313. Molecular regulators of brain function: a new view
314. A receptors and benzodiazepine receptors in the brain shown by monoclonal antibodies
315. The mismatch problem in receptor autoradiography and the coexistence of multiple messengers
316. Pharmacology of enkephalinase inhibitors
317. Antibodies against γ-aminobutyric acid: specificity studies and immunocytochemical results
318. Binding sites for calcitonin gene-related peptide in distinct areas of rat brain
319. A comparative study on characterization and distribution of cholecystokinin binding sites among the rat, mouse and guinea pig brain
320. Autoradiographic visualization of CNS receptors for vasoactive intestinal peptide
321. Localisation and characterization of aminopeptidases in the CNS and the hydrolysis of enkephalin
322. Angiotensin II binding sites in the anteroventral-third ventricle (AV3V) area and related structures of the rat brain
323. Experimental immunohistochemical studies on the substance P neuron system in the lateral habenular nucleus of the rat: distribution and origins
324. Demonstration and distribution of kassinin-like material (substance K) and distribution of iodinated substance K binding sites in the rat central nervous system
325. A comparison of the anatomical distribution of substance P and substance P receptors in the rat central nervous system
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329. Calcitonin gene-related peptide: detailed immunohistochemical distribution in the central nervous systera
330. Distribution of corticotropin releasing factor-like immunoreactivity in the rat brain by immunohistochemistry and radioimmunoassay: comparison and characterization of ovine and rat/human CRF antisera
331. Brain peptides as neurotransmitters
332. Identified axo-axonic celis are immunoreactive for GABA in the hippocampus and visual cortex of the cat
333. Synaptic connections of enkephalin-immunoreactive nerve terminals in the neostriatum: a correlated light and electron microcopic study
334. Direct autoradiographic determination of M1 and M2 muscarinic acetylcholine receptor distribution in the rat brain: relation to cholinergic nuclei and projections
335. Distributions of serotonin-immunoreactivity in the central nervous system of the rat—cell bodies and terminals
336. Comparative mapping of opiate receptors and enkephalin immunoreactive nerve terminals in the rat hippocampus
337. Two dopamine receptors: biochemistry, physiology and pharmacology
338. Antibodies to the β-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain
339. 3H]captopril: Localization to a striatonigral pathway
340. The central adrenergic system. An immunofluorescence study of the location of cell bodies and their efferent connections in the rat utilizing dopamine-β -hydroxylase as a marker
341. Organization of ovine corticotropin-releasing factor immunoreactive celis and fibers in the rat brain: an immunohistochemical study
342. Localization of neurotensin binding sites to dopaminergic and putative cholinergic neurons in rat central nervous system
343. The GABA-ergic system: a locus of benzodiazepine action
344. Demonstration of inter- and intraspecies differences in serotonin binding sites by antibodies from an autistic child
345. Topographical organization of the cholinergic innervation, muscarinic receptor sites and cGMP-immunoreactivity in rat brain
346. Substance P receptors in primary cultures of cortical astrocytes from the mouse
347. Endogenous anticonvulsant substance in the rat cerebrospinal fluid after a generalized seizure
348. Evidence that GABAergic terminals and glycine receptors can be associated at the same central synapses
349. Distribution of glycine receptors at central synapses: an immunoelectron microscopy study
350. Catching up with peptides
351. Neurotensin: immunohistochemical localization in rat central nervous system.
352. Somatostatin receptors: distribution in rat central nervous system and human frontal cortex
353. 2 agonist binding sites in the rat and the human central nervous system: analysis of some functional, anatomic correlates of the pharmacologic effects of clonidine and related adrenergic agents
354. 3H]kainic acid binding sites in the rat forebrain
355. Tyrosine hydroxylase-immunoreactive neurons of the hypothalamus: a light and electron microscopic study
356. Radioautographic localization of specific binding sites for blood-borne angiotensin II in the rat brain
357. Morphological evidence for a dopaminergic terminal field in the hippocampal formation of the voung and adult rat
358. Regional concentrations of noradrenaline and dopamine in rat brain
359. Central somatostatin systems revealed with monoclonal antibodies
360. Evidence that transmitters can be released from regions of the nerve cell other than presynaptic axon terminal: axonal release of acetycholine without modulation
361. Autoradiographic comparison of the distribution of the neutral endopeptidase “enkephalinase” and of μ and δ opioid receptors in rat brain
362. Autoradiographic determination of brain regions where the distribution of benzodiazepine and low-affinity GABA receptors overlap
363. Muscarinic cholinergic receptors: Autoradiographic localization of high and low affinity agonist binding sites
364. Distribution of opiate reeeptors in the monkey brain: an autoradiographic study
365. B receptors in rat cerebellum
366. 7
367. Opiate receptor distributions in the cerebral cortex of the rhesus monkey
368. 125I]physalaemin
369. Brain and pituitary receptors for corticotropin releasing factor: localization and differential regulation after adrenalectomy
370. 125I-Lysergic acid diethylamide binds to a novel serotonergic site on rat choroid plexus epithelial celis
371. Spinal opiate analgesia: charactenstics and principles of action
372. Distribution of neuropeptide Y in the lower brainstem: an immunohistochemical analysis
373. Autoradiographic localization of benzodiazepine receptors in the brains of humans and animals
374. Noradrenergic alpha-1 and alpha-2 receptors: light microscopic autoradiographic localization
375. Radiohistochemical localization of benzodiazepine receptors in rat brain
376. Neurotensin receptor localization by light microscopic autoradiography in rat brain
377. Corticotropin-releasing factor mRNA is expressed in the inferior olives of rodents and primates
378. Opiate receptors undergo axoplasmic flow
379. Autoradiographic localization of cholecystokinin receptors in rodent brain
380. 3H]strychnine
381. Exocytosis from large dense cored vesicles outside the active synaptic zones of terminals within the trigeminal subnucleus caudalis: a possible mechanism for neuropeptide release