The antimalarial action on Plasmodium falciparum of qinghaosu and artesunate in combination with agents which modulate oxidant stress

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 81, Issue 5, 1987, Pages 710-714

  Krungkrai, Sudaratana Rochanakij ^a   Yuthavong, Yongyuth ^b  

^a RAJAVITHI HOSPITAL   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEMISININ; ARTESUNATE; DOXORUBICIN; MICONAZOLE;

DRUG POTENTIATION; HUMAN; OXYGEN TENSION; PLASMODIUM FALCIPARUM; PROTOZOON; SHORT SURVEY;

ANIMAL; ANTIMALARIALS; DOXORUBICIN; DRUG SYNERGISM; MICONAZOLE; OXYGEN CONSUMPTION; PLASMODIUM FALCIPARUM; SESQUITERPENES; SUPPORT, NON-U.S. GOV'T;

EID: 0023622465     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/0035-9203(87)90003-4     Document Type: Article

References (27)

1. A radical interpretation of immunity to malaria parasites
2. Cytochemical localization of NADH oxidase in Candida albicans
3. Evidence for reactive oxygen intermediates causing hemolysis and parasite death in malaria
4. 3+ complex to membrane phospholipids
5. Cytochemical and biochemical studies of yeast after in vitro exposure to miconazole
6. Oxidative destruction of DNA by adriamycin-iron complex
7. Biology of disease: free radicals and tissue injury
8. 3H-isoleucine by Plasmodium falciparum in vitro
9. 3H-dihydroartemisinine by erythrocytes infected with Plasmodium falciparum in vitro
10. Antimalarial activity of mefloquine and qinghaosu
11. Qinghaosu (artemisinin): an antimalarial drug from China
12. Syncrhonization of Plasmodium falciparum erythrocytic stages in culture
13. 3H-hypoxanthine by Plasmodium falciparum in vitro
14. Induction of crisis forms in the human malaria parasite Plasmodium falciparum by γ-interferon-activated, monocyte-derived macrophages
15. Oxygen enhances the antimalarial activity of the imidazoles
16. Antimalaria studies on qinghaosu
17. Drug sensitivity of P. falciparum: an in vitro microtechnique
18. Mechanism of action of qinghaosu (artemisinine) and related compounds
19. Plasmodium falciparum: microaerophilic requirements in human red blood cells
20. Studies on the mechanism of action of miconazole: effect of miconazole on respiration and cell permeability of Candida albicans
21. Human malaria parasites in continuous culture
22. Biochemical effects of miconazole on fungi: II. Inhibition of ergosterol biosynthesis in Candida albicans
23. A re-evaluation of the status of cholesterol in erythrocytes infected by Plasmodium knowlesi and P. falciparum
24. The development of qinghaosu and its derivatives as antimalaria agents
25. Killing of human malaria parasites by macrophage secretory products
26. Antimalarial agents, 2. Artesunate, an inhibitor of cytochrome oxidase activity in Plasmodium berghei