Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease

Journal of Experimental Medicine

Volumn 166, Issue 5, 1987, Pages 1280-1289

  Piguet, Pierre Francois ^a   Grad, Georges E ^a   Allet, Bernard ^b   Vassalli, Pierre ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b Biogen Idec International GmbH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; TUMOR NECROSIS FACTOR;

ANIMAL CELL; GRAFT VERSUS HOST REACTION; INTESTINE INJURY; INTRAVENOUS DRUG ADMINISTRATION; MOUSE; NONHUMAN; T LYMPHOCYTE;

ANIMAL; BODY WEIGHT; BONE MARROW TRANSPLANTATION; EPITHELIUM; GRAFT VS HOST DISEASE; GROWTH INHIBITORS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN G; INTESTINES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; SKIN; SPLEEN; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR;

EID: 0023620524     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.166.5.1280     Document Type: Article

References (28)

1. Slavin, R. E., and G. V. Santos. 1973. The graft versus host reaction in man after bone marrow transplantation: pathology, pathogenesis, clinical features, and implication. Clin. Immunol. Immunopathol. 1:472.
2. Rappaport, H., A. Khalil, O. Halle-Pannenko, L. Pritchard, D. Dantchev, and G. Mathé. 1979. Histopathologic sequence of events in adult mice undergoing lethal graft versus host reaction developed across H-2 and/or non-H-2 histocompatibility barriers. Am.f. Pathol. 96:121.
3. Sale, G. E. 1984. Pathology and recent pathogenic studies in human graft-versus-host disease. Surv. Synth. Pathol. Res. 31:235.
4. Piguet, P. F. 1985. GVHR elicited by product of class I or II loci of the MHC: Analysis of the response of mouse T lymphocytes to products of class I and class II loci of the MHC in correlation with GVHR-induced mortality, medullary aplasia, and enteropathy. J. Immunol. 135:1637.
5. Guy-Grand, D., and P. Vassalli. 1986. Gut injury in mouse graft-versus-host-reaction: study of its occurrence and mechanisms. J. Clin. Invest. 77:1584.
6. Guillen, F. J., J. Ferrara, W. H. Hancok, D. Messadi, E. Fonferko, S.J. Burakoff, and G. F. Murphy. 1986. Acute cutaneous graft versus host disease to minor histocompatibility antigen in a murine model: evidence that large granular lymphocytes are effector cells in the immune response. Lab. Invest. 55:35.
7. Rolink, A. G., and E. Gleichmann. 1983. Allosuppressor and allohelper T cells in acute and chronic graft-vs.-host disease. III. Different Lyt subsets of donor T cells induce different pathological syndromes. J. Exp. Med. 158:546.
8. Beutler, B., and A. Cerami. 1987. Cachectin: more than a tumor necrosis factor. N. Engl. J. Med. 316:379.
9. Le, J., and J. Vilcek. 1987. Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities. Lab. Invest. 56:234.
10. Sale, G. E., H. M. Shulman, B. B. Gallucci, and E. D. Thomas. 1985. Young rete ridge keratinocytes are preferred targets in cutaneous graft-versus-host disease. Am. f. Pathol. 118:278.
11. Snover, D. C, S. A. Weisdorf, G. M. Vercellotti, B. Rank, S. Hutton, and P. Mcglave. 1984. A histopathologic study of gastric and small intestinal graft versus host disease following allogeneic bone marrow transplantation. Hum. Pathol. 16:387.
12. Liang, C. M., S. M. Liang, T. Jost, A. Sand, I. Dougas, and B. Allet. 1986. Production and characterization of monoclonal antibodies against recombinant human tumor necrosis factor/cachectin. Biochem. Biophys. Res. Commun. 137:847.
13. Ruff, M. R., and G. E. Gifford. 1986. J. Immunol. 125:1671.
14. Grau, G. E., L. F. Fajardo, P. F. Piguet, B. Allet, P. H. Lambert, and P. Vassalli. 1987. Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science (Wash. DC). 237:1210.
15. + T lymphocytes. J. Immunol. 139:406.
16. Kerr, J. F. R., C.J. Bishop, and J. Searle. 1984. Apoptosis. In Recent Advances in Histopathology. Peter P. Anthony, N. Roderick, M. Macsween, editors. Churchill-Livingstone, London. 1-15.
17. Duvall, E., and A. H. Willie. 1986. Death and the cell. Immunol. Today. 7:115.
18. Mason, D. W., M. Dallman, and A. N. Barclay. 1981. Graft-versus-host disease induces expression of la antigen in rat epidermal cells and gut epithelium. Nature (Land.). 293:150.34.
19. Collart, M., D. Belin, J. D. Vassalli, S. de Kossodo, and P. Vassalli. 1986. γ-Interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleu-kin 1, and urokinase genes, which are controlled by short lived repressors. J. Exp. Med. 164:2113.
20. Peters, P. M., J. R. Ortaldo, M. R. Shalaby, L. P. Svedersky, G. E. Nedwin, T. S. Bringman, P. E. Hass, B. B. Aggarwal, R. B. Herberman, D. V. Goeddel, and M. A. Palladino. 1986. Natural killer-sensitive targets stimulate production of TNF-a but not TNF-/3 (lymphotoxin) by highly purified human peripheral blood large granular lymphocytes. J. Immunol. 137:2592.
21. Pennica, D., G. E. Nedwin, J. S. Hayflick, P. H. Seeburg, R. Derynck, M. A. Palladino, W.J. Kohr, B. B. Aggarwal, and D. V. Goeddel. 1984. Human tumor necrosis factor: precursor structure, expression and homology to lymphotoxin. Nature (Lond.). 312:724.
22. Nedwin, G. E., L. P. Svedersky, T. S. Bringman, M. A. Palladino, and D. V. Goeddel. 1985. Effect of interleukin 2, interferon-γ, and mitogens on the production of tumor necrosis factors α and β. J. Immunol. 135:2492.
23. Tracey, K. J., B. Beutler, S. F. Lowry, J. Merryweather, S. Wolpe, I. W. Milsark, R. J. Hariri, T.J. Fahey, A. Zentella, J. D. Albert, G. T. Shires, and A. Cerami. 1986. Shock and tissue injury induced by recombinant human cachectin. Science (Wash. DC). 234:470.
24. Gamble, J. R., J. M. Harlan, S.J. Klebanoff, and M. A. Vadas. 1985. Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor. Proc. Natl. Acad. Sci. USA. 82:8667.
25. Dinarello, C. A., J. G. Cannon, S. M. Wolff, H. A. Bernheim, B. Beutler, A. Cerami, I. S. Figari, M. A. Palladino, and J. V. O’Connor. 1986. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J. Exp. Med. 163:1433.
26. Pober, J. S., M. A. Gimbrone, L. A. Lapierre, D. L. Mendrick, W. Fiers, R. Rothlein, and T. A. Springer. 1986. Overlapping pattern of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. J. Immunol. 137:1893.
27. Brown, G. L., L. Curtsinger, J. R. Brightwell, D. M. Ackerman, G. R. Tobin, H. C. Polk, C. George-Nascimento, P. Valenzuela, and G. S. Schulz. 1986. Enhancement of epidermal regeneration by biosynthetic epidermal growth factor. J. Exp. Med. 163:1319.
28. Ulshen, M. H., L. E. Lyn-Cook, and R. H. Raasch. 1986. Effect of intraluminal epidermal growth factor on mucosal proliferation in the small intestine of adult rats. Gastroenterology. 91:1134.